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EMBO Reports @emboreports.org · 20h

First October issue is life.

www.embopress.org/toc/14693178...

Cover features work by Martin Kaltenpoth and co-workers
@kaltenpoth-lab.bsky.social @mpi-ce.bsky.social showing that symbionts adjust gene expression according to host life-stage and environment.

-> www.embopress.org/doi/full/10....

EMBO Reports @emboreports.org · 1d

Yun Zhang and Andrew Samuelson @urochester.bsky.social show that #aging impairs #viral #defense in Caenorhabditis elegans due to loss of DRH-1/RIG-I deSUMOylation by ULP-4/SENP7.

-> www.embopress.org/doi/full/10....

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EMBO Reports @emboreports.org · 4d

Howard Wolinsky, Holger Breithaupt, and Yehu Moran @yehumoran.bsky.social on #scientists targeted by dark PR tactics.

Scientists critical of de-extinction projects as targets of anonymous smear articles and weaponized copyright infringement claims.

Read more:

www.embopress.org/doi/full/10....

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EMBO Reports @emboreports.org · 6d

For the love of frontier research, or why Elon’s rockets keep blowing up.

The current Zeitgeist favouring utilitarian research risks undermining basic research—the very foundation on which innovative technological advances depend.

By Nektarios Tavernarakis:

www.embopress.org/doi/full/10....

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EMBO Reports @emboreports.org · 6d

Read the new opinion piece by David Smith.

www.embopress.org/doi/full/10....

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EMBO Reports @emboreports.org · 13d

Frank Uhlmann and Bhavin Khatri @crick.ac.uk and
@imperialcollegeldn.bsky.social and co-workers describe progressive #chromosome shape changes during cell divisions, showing that mitotic chromosomes gradually shorten and thicken.

-> www.embopress.org/doi/full/10....

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Reposted by EMBO Reports

EMBO @embo.org · 16d

One week left – Sign up now! Early registration deadline closes 30 September for the ASCB | EMBO #CellBio2025 Meeting taking place 6–10 December in Philadelphia, US: www.ascb.org/cellbio2025/... 🧪 #LifeSciences #CellBiology #research #conference

Cell Bio 2023-An ASCB|EMBO Meeting

Network, learn, and collaborate with top cell biologists from around the globe.

www.ascb.org

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EMBO Reports @emboreports.org · 16d

The second September issue is online.

-> www.embopress.org/toc/14693178...

The cover features work by Tomoya Kitajima and co-workers @riken-bdr.bsky.social and @crick.ac.uk showing spatially different requirements for the KIF11 #motor in the #oocyte #spindle.

www.embopress.org/doi/full/10....

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EMBO Reports @emboreports.org · 16d

Jacqueline Beaudry @utoronto.ca and co-workers show that acute exogenous acyl-GIP treatment enhances #lipid handling and fatty acid oxidation by involving brown #fat in rodent models of #obesity.

www.embopress.org/doi/full/10....

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EMBO Reports @emboreports.org · 18d

Kegawa et al show that #Toxoplasma gondii invasion causes a transient increase in conductance within the host cell plasma #membrane explained by creation of multiple pores.
#MembraneBiology #apicomplexan

-> www.embopress.org/doi/full/10....

See also Male et al
-> www.embopress.org/doi/full/10....

EMBO Reports @emboreports.org · 18d

Male et al show that early during invasion, #Toxoplasma gondii creates a transient perforation pore in the host cell membrane dependent on rhoptry #exocytosis.
#MembraneBiology #apicomplexan

-> www.embopress.org/doi/full/10....

See also Kegawa et al
-> www.embopress.org/doi/full/10....

EMBO Reports @emboreports.org · 20d

Sandra Iden @sandraiden.bsky.social @idenlab.bsky.social @uni-saarland.de @pharmascihub.bsky.social and co-workers show that #melanocyte #differentiation and #mechanosensation are differentially modulated by distinct extracellular matrix proteins. #ECM #MITF

www.embopress.org/doi/full/10....

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EMBO Reports @emboreports.org · 22d

The tyrosine #phosphatase PTPN22 functions as a scaffold protein to maintain mTORC2 complex integrity and function, independent of its phosphatase activity.
#cellsignaling

-> www.embopress.org/doi/full/10....

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EMBO Reports @emboreports.org · 22d

The muscle specific MEF2Dα2 isoform is generated by postnatal alternative #splicing. It regulates skeletal muscle ketogenic gene expression, blood ketone levels and exercise capacity.
#metabolism

-> www.embopress.org/doi/full/10....

EMBO Reports @emboreports.org · 24d

A comprehensive molecular atlas of mesenchymal cell types in the adult mouse #liver.

-> www.embopress.org/doi/full/10....

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EMBO Reports @emboreports.org · 24d

CDK1 phosphorylation of lactate dehydrogenase A (LDHA) promotes LADB tetramers directing lactate towards NADH production instead of #glycolysis. NADH fuels oxidative phosphorylation and ATP production sustaining #mitosis of #cancer cells.
#metabolism

-> www.embopress.org/doi/full/10....

EMBO Reports @emboreports.org · 27d

Sunil Kumar Pradhan @sunil-k-pradhan.bsky.social, M Cristina Cardoso and co-workers from the Technical University of Darmstadt show that dynamic association of H3K36me3 with pericentromeric #heterochromatin regulates its #replication time.

www.embopress.org/doi/full/10....

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EMBO Reports @emboreports.org · 29d

Excessive dietary sugar reprograms the metabolic state of #Drosophila larval macrophages. Enhanced glycolysis and lipolysis suppresses organ growth and dominates over growth-supportive lipogenesis.
#metabolism #immune

-> www.embopress.org/doi/full/10....

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EMBO Reports @emboreports.org · 29d

Lipoteichoic acid present on extracellular vesicles #EVs from S. pyogenes is sensed by TLR2 and induces activation of an alternative #inflammasome pathway composed of NLRP3 and caspases-4/5 in human monocytes.

-> www.embopress.org/doi/full/10....

EMBO Reports @emboreports.org · 29d

It is our 25th birthday this year.

Read thoughts by our chief editor Bernd Pulverer @berndpulverer.bsky.social, by Howy Jacobs and by Frank Gannon.

EMBO reports at 25 - Brief but not bland

www.embopress.org/doi/full/10....

www.embopress.org/doi/full/10....

www.embopress.org/doi/full/10....

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EMBO Reports @emboreports.org · Sep 9

The first September issue is live.

www.embopress.org/toc/14693178...

The cover features work by Cassie Clarke @cassiejclarke.bsky.social @cruk-si.bsky.social and co-workers showing that UPP1 supports #metastasis by altering #immune and ECM landscapes.

-> www.embopress.org/doi/full/10....

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EMBO Reports @emboreports.org · Sep 4

Cargoes move from cis to trans-Golgi compartments and concentrate in the TGN before exiting
#Golgi #MembraneTrafficking

-> www.embopress.org/doi/full/10....

EMBO Reports @emboreports.org · Sep 4

A new review is online!

Lin Luo, Katja Simon and colleagues @mdc-berlin.bsky.social discuss how #aging T cells cope with damaged #mitochondria

-> www.embopress.org/doi/full/10....

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EMBO Reports @emboreports.org · Sep 4

P300/CBP drives pathogenic enhancer activity and gene expression in Ewing sarcoma
#cancer #chromatin

-> www.embopress.org/doi/full/10....

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EMBO Reports @emboreports.org · Sep 4

lncRNAs SVALKA and SVALNA negatively regulate CBF gene expression in #Arabidopsis during cold stress.
#PlantScience

-> www.embopress.org/doi/full/10....

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