Dr Emma S Chambers
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emmaschambers.bsky.social
Dr Emma S Chambers
@emmaschambers.bsky.social
Senior Lecturer in Immunology based at Blizard Institute, QMUL. My research focussed on life course immunology and the influence of age and sex, and life-course events such as menopause on the immune system in health and disease.
I am very grateful to my funders the @vivensa.bsky.social and @bartscharity.bsky.social for funding this research through seed awards. More research is desperately needed to understand the impact of menopause on immunity and I hope more funders consider this as an important research area. #immunosky
October 9, 2025 at 10:25 AM
This study was an amazing Early Career researcher effort with Roel de Maeyer performing the functional monocyte assays, @oliviabracken.bsky.social performing the bioinformatic analysis, and my lovely lab member Justyna performing the Menopause analysis. I am very grateful for all their hard work.
October 9, 2025 at 10:23 AM
Importantly the use of Hormone Replacement Therapy (HRT) in menopausal females kept their monocytes looking ‘young’ and they had improved phagocytosis as compared to age matched controls. Highlighting the potential immune benefits of HRT.
October 9, 2025 at 10:22 AM
In this paper we demonstrate that there is an increase in inflammatory monocytes with altered proteome in post-menopausal females, which is not observed with age in males. Phagocytosis is significantly decreased in post-menopausal as compared to pre-menopausal females.
October 9, 2025 at 10:22 AM