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Utility of the C-Peptide/Insulin Molar Ratio for Distinguishing Type A Insulin Resistance Syndrome From Type 2 Diabetes

Endocrine Society Journals @endosocjournals.bsky.social · 1d

Utility of the C-Peptide/Insulin Molar Ratio for Distinguishing Type A Insulin Resistance Syndrome From Type 2 Diabetes. Read more in #JCEM : bit.ly/42w8KnR
#C-peptidereactivity #hyperinsulinemia #immunoreactiveinsulin
@endocrinesociety.bsky.social

AbstractObjective. Type A insulin resistance syndrome (IRS), characterized by impaired insulin receptor function due to variants of the insulin receptor ge

Role of PROP1 in Postnatal Pituitary Gland Maturation

Endocrine Society Journals @endosocjournals.bsky.social · 2d

Role of PROP1 in Postnatal Pituitary Gland Maturation. Read more in #Endocrinology : bit.ly/4nDzbAx
#SOX2 #stemcells #POU1F1-lineage @endocrinesociety.bsky.social

Abstract. Mutations in the pituitary-specific transcription factor PROP1 are the most common known cause of hypopituitarism in humans. Prop1 is the first p

Recombinant Human GH in Managing Refractory Hypoglycemia in a Young Patient With Embryonal Rhabdomyosarcoma

Endocrine Society Journals @endosocjournals.bsky.social · 5d

Recombinant Human GH in Managing Refractory Hypoglycemia in a Young Patient with Embryonal Rhabdomyosarcoma. Read more in #JCEM Case Reports: bit.ly/42w8bdJ #IGF-2 #somatropin @endocrinesociety.bsky.social

Abstract. Non-islet cell tumor hypoglycemia (NICTH) is a rare paraneoplastic syndrome associated with various malignancies, mediated by the overproduction

Perspectives From Adolescents and Young Adults With Klinefelter Syndrome on Testosterone Supplementation and Fertility

Endocrine Society Journals @endosocjournals.bsky.social · 6d

Perspectives From Adolescents and Young Adults with #Klinefelter Syndrome on Testosterone Supplementation and Fertility. Read more in #JES: bit.ly/4pG4CeO #TESE #Infertility @endocrinesociety.bsky.social

AbstractContext. Infertility and testicular dysfunction are typical features of Klinefelter syndrome (KS; 47,XXY). KS affects ∼1:600 male births, making it

Altered Expression of Aromatase and Estrogen Receptors in Adipose Tissue From Men With Obesity or Type 2 Diabetes

Endocrine Society Journals @endosocjournals.bsky.social · 6d

Browse the latest Thematic Issue from @endocrinesociety.bsky.social Journals focusing on #Neuroendocrinology. This collection ranges from clinical reports of hypothalamic-pituitary disorders to basic science investigations. Read now: bit.ly/3IPhLl1 @oxfordacademic.bsky.social #EndoSky

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Endocrine Society Journals @endosocjournals.bsky.social · 7d

Altered expression of #aromatase and estrogen receptors in adipose tissue from men with obesity or type 2 diabetes. Read more in #JCEMCaseReports: bit.ly/4ngNISd #estradiol #obesity #T2D @endocrinesociety.bsky.social

AbstractContext. Obesity and insulin resistance in men are linked to decreased testosterone and increased estradiol (E2) levels. Aromatase (ARO) converts t

Fatal, Fulminant, Necrotizing Pancreatitis Associated With Recent Tirzepatide Initiation

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Endocrine Society Journals @endosocjournals.bsky.social · Jul 6

Attending #ENDO2025? Explore the science behind the sessions with our new Thematic Issue—featuring articles by invited speakers & session chairs.🩺 Dive into expert insights from our journals: bit.ly/4kk0kFR

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Endocrine Society Journals @endosocjournals.bsky.social · Jun 30

Fatal, fulminant, necrotizing #pancreatitis associated with recent #tirzepatide initiation
doi.org/10.1210/jcem.... Featured in #JCEMCaseReports #OpenAccess
@endocrinesociety.bsky.social

Abstract. As obesity is increasing in prevalence and its associated morbidity and mortality are escalating worldwide, medications like tirzepatide are freq

Growth Hormone Replacement in Craniopharyngioma: Analysis of the Hypopituitary Control and Complications Study (HypoCCS)

Endocrine Society Journals @endosocjournals.bsky.social · Jun 30

#GrowthHormone replacement in #craniopharyngioma: analysis of the hypopituitary control and complications study (HypoCCS). #OpenAccess. Featured study in #JES. #pituitary
doi.org/10.1210/jend...
@endocrinesociety.bsky.social

AbstractContext. Patients with adult-onset craniopharyngioma (CP) show metabolic dysfunction and panhypopituitarism. Growth hormone (GH) deficiency is ofte

Bone in Parathyroid Diseases Revisited: Evidence From Epidemiological, Surgical and New Drug Outcomes

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Endocrine Society Journals @endosocjournals.bsky.social · Jun 30

#Bone in #parathyroid diseases revisited: evidence from epidemiological, surgical and new drug outcomes. Featured review in #EndocrineReviews. #OpenAccess #epidemiology #surgery
@endocrinesociety.bsky.social
doi.org/10.1210/endr...

Abstract. PTH-related disorders have a major impact on bone metabolism and skeletal properties because of the pivotal role of PTH in calcium and phosphate

Predictors of Fracture in Middle-Aged and Older Adults With Type 2 Diabetes and Overweight or Obesity

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Endocrine Society Journals @endosocjournals.bsky.social · Jun 30

Predictors of #fracture in middle-aged and older adults with type 2 #diabetes and overweight or #obesity. Featured study in #JCEM. #FreeToView #bone
doi.org/10.1210/clin...
@endocrinesociety.bsky.social

AbstractContext. Persons with type 2 diabetes have increased fracture risk that existing fracture risk assessment tools underestimate.Objective. Identify f

Mechanisms of Flame Retardant Toxicity and Their Impacts on Anxiety and Cognition in the Brain

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Endocrine Society Journals @endosocjournals.bsky.social · Jun 30

Mechanisms of flame retardant toxicity and their impacts on #anxiety and #cognition in the brain. doi.org/10.1210/endo... Featured review in #Endocrinology. #FreeToView #EDCs
@endocrinesociety.bsky.social

Abstract. Flame retardants have been used extensively to reduce flammability in household and industrial materials raising significant concerns due to thei

Functional Suppression of a Prolactinoma by a Dopamine-Secreting Paraganglioma

Endocrine Society Journals @endosocjournals.bsky.social · Jun 23

Functional suppression of a #prolactinoma by a dopamine-secreting #paraganglioma. Featured in #JCEMCaseReports. #OpenAccess #dopamine
academic.oup.com/jcemcr/artic...
@endocrinesociety.bsky.social

Abstract. Prolactin-secreting pituitary adenomas are typically treated with dopamine agonists to inhibit prolactin secretion and reduce tumor size. Dopamin

Effect of Time-Restricted Eating on β-Cell Function in Adults With Type 2 Diabetes

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Endocrine Society Journals @endosocjournals.bsky.social · Jun 23

Effect of time-restricted eating on β-cell function in adults with type 2 #diabetes. Featured study in #JCEM #FreeToView #BetaCell #T2D academic.oup.com/jcem/article...
@endocrinesociety.bsky.social

AbstractContext. Time-restricted eating (TRE), which consists of restricting the eating window to typically 4 to 8 hours (while fasting for the remaining h

The Glucagon Receptor Is Expressed in the Frontal Cortex and Impaired Signaling Associates With Cognitive Decline

Endocrine Society Journals @endosocjournals.bsky.social · Jun 23

The glucagon receptor is expressed in the frontal cortex and impaired signaling associates with cognitive decline #OpenAccess Featured study in #JES #cognition #GlucagonReceptor #neuroendocrinology academic.oup.com/jes/article/...
@endocrinesociety.bsky.social

Abstract. Individuals with type 2 diabetes (T2D) have an elevated risk of cognitive decline, yet the mechanisms connecting these pathologies remain unclear

Bone in Parathyroid Diseases Revisited: Evidence From Epidemiological, Surgical and New Drug Outcomes

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Endocrine Society Journals @endosocjournals.bsky.social · Jun 23

Bone in #parathyroid diseases revisited: evidence from epidemiological, surgical and new drug outcomes. Featured in #EndocrineReviews. #OpenAccess #bone academic.oup.com/edrv/advance...
@endocrinesociety.bsky.social

Abstract. PTH-related disorders have a major impact on bone metabolism and skeletal properties because of the pivotal role of PTH in calcium and phosphate

Functional Analysis of HSD17B3-Deficient Male Mice Reveals Roles for HSD17B7 and HSD17B12 in Testosterone Biosynthesis

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Endocrine Society Journals @endosocjournals.bsky.social · Jun 20

Functional analysis of HSD17B3-deficient male mice reveals roles for HSD17B7 and HSD17B12 in #testosterone biosynthesis
#OpenAccess Featured study in #Endocrinology
doi.org/10.1210/endo...
@endocrinesociety.bsky.social

Abstract. Historically, 17β-hydroxysteroid dehydrogenase type 3 (HSD17B3) was thought to be the key enzyme responsible for testicular testosterone producti

Transient Blindness in Metformin-associated Lactic Acidosis: Resolution With Supportive Care

Endocrine Society Journals @endosocjournals.bsky.social · Jun 12

Transient #Blindness in #Metformin -associated Lactic #Acidosis: Resolution With Supportive Care. Featured in #JCEMCaseReports #T2D
doi.org/10.1210/jcem...
@endocrinesociety.bsky.social

Abstract. Metformin remains the first-line pharmacologic treatment for type 2 diabetes mellitus due to its well-established efficacy and safety profile. Ho

Sex-specific Association of Chronic Proton Pump Inhibitor Use With Reduced Bone Density and Quality

Endocrine Society Journals @endosocjournals.bsky.social · Jun 12

Sex-specific Association of Chronic Proton Pump Inhibitor Use With Reduced #Bone Density and Quality. Featured study in #JCEM. #FreeToView. #PPI
doi.org/10.1210/clin...
@endocrinesociety.bsky.social

AbstractContext. Chronic use of proton pump inhibitors (PPIs) has been associated with an increase in bone fragility. However, evidence on the effect of ch

The Oxytocin System and Implications for Oxytocin Deficiency in Hypothalamic-Pituitary Disease

Endocrine Society Journals @endosocjournals.bsky.social · Jun 12

The Oxytocin System and Implications for #Oxytocin Deficiency in Hypothalamic-Pituitary Disease. Featured in #EndocrineReviews. #pituitary. #FreeToView
doi.org/10.1210/endr...
@endocrinesociety.bsky.social

Abstract. Oxytocin (OXT) is a hypothalamic-posterior pituitary hormone with multiple effects, ranging from regulation of energy homeostasis to bone health

Endocrine Society Journals @endosocjournals.bsky.social · Jun 12

Association of OGTT-curve Shape With Anthropometric, Metabolic, and Inflammatory Parameters in Healthy Adults. Featured study in #JES. #OpenAccess. #diabetes
doi.org/10.1210/jend...
@endocrinesociety.bsky.social

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T3–THR Signaling Governed by DIO2 Contributes to Endometrial Receptivity by Regulating Epithelial Cell Membrane Fluidity

Endocrine Society Journals @endosocjournals.bsky.social · Jun 12

T3–THR Signaling Governed by DIO2 Contributes to Endometrial Receptivity by Regulating Epithelial Cell Membrane Fluidity. Featured study in #Endocrinology.
#FreeToView #fertility
@endocrinesociety.bsky.social
academic.oup.com/endo/article...

Abstract. Maintaining normal thyroid function is crucial in pregnancy, and the thyroid hormone signaling pathway is involved in embryo implantation. Howeve

An Unusual Case of Factitious Disorder Manifesting as Hypercalcemia Mediated by Exogenous Calcitriol

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Endocrine Society Journals @endosocjournals.bsky.social · May 16

An unusual case: factitious disorder manifesting as #hypercalcemia mediated by exogenous #calcitriol. Featured case report in #JCEMCaseReports. #OpenAccess #PTH
@endocrinesociety.bsky.social
doi.org/10.1210/jcem...

Abstract. Excessive 1, 25-dihydroxy vitamin D (calcitriol) is a pathophysiological cause of hypercalcemia. This form of hypercalcemia is seen in autoimmune

Glucose-Dependent Insulinotropic Polypeptide in Incretin Physiology: Role in Health and Disease

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Endocrine Society Journals @endosocjournals.bsky.social · May 16

Glucose-dependent insulinotropic polypeptide in #incretin physiology: role in health and disease. Featured review in #EndocrineReviews. #FreeToView #GIP #obesity
@endocrinesociety.bsky.social
doi.org/10.1210/endr...

Abstract. Glucose-dependent insulinotropic polypeptide (GIP) is a 42-amino acid hormone that is synthesized and released from upper intestinal enteroendocr