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Reposted by Enrica Boda & team

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 1d

Myelin pathology is a key feature of X-linked Dystonia Parkinsonism https://www.biorxiv.org/content/10.1101/2025.10.07.680990v1

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Reposted by Enrica Boda & team

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 5d

GlialCAM Cytoplasmic Signaling in Oligodendrocytes and Astrocytes is Essential for White Matter Homeostasis in the Brain https://www.biorxiv.org/content/10.1101/2025.10.03.680331v1

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Reposted by Enrica Boda & team

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 7d

Spared nerve injury induces long-term and brain region-specific changes in oligodendrocyte density in mice https://www.biorxiv.org/content/10.1101/2025.10.01.679851v1

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Reposted by Enrica Boda & team

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 8d

Brain injury reactivates a developmental program driving genesis and integration of transient LGE-class interneurons https://www.biorxiv.org/content/10.1101/2025.09.30.679475v1

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Reposted by Enrica Boda & team

barakboaz.bsky.social @barakboaz.bsky.social · 12d

🚀 Our new paper is out in Nature Communications!

We uncovered a mechanistic switch to boost myelination: deleting Gtf2i in myelinating glia enhances Sox10/Mbp activity → thicker myelin, faster conduction, improved motor coordination.

Open access link:

www.nature.com/articles/s41...

Gtf2i-encoded transcription factor Tfii-i regulates myelination via Sox10 and Mbp regulatory elements - Nature Communications

The transcriptional regulation of oligodendrocytes has an essential role in myelin formation and maintenance. Here, the authors identify the transcription factor Tfii-i as a regulator of myelin genes expression in the nervous system and show that its loss enhances myelin thickness and nerve conduction.

www.nature.com

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Reposted by Enrica Boda & team

Vanja Tepavcevic @tepavcevicvanja.bsky.social · 9d

"Post-Synaptic Density Proteins in Oligodendrocytes are Required for Activity-Dependent Myelin Sheath Growth"
www.sciencedirect.com/science/arti...

Post-Synaptic Density Proteins in Oligodendrocytes are Required for Activity-Dependent Myelin Sheath Growth

Neuronal activity regulates myelination in the central nervous system, highlighting the critical importance of axon-oligodendrocyte communications in …

www.sciencedirect.com

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Reposted by Enrica Boda & team

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 11d

Tmem117, an oligodendrocyte-enriched regulator of NCX activity, links myelin homeostasis to counterregulation and metabolic health. https://www.biorxiv.org/content/10.1101/2025.09.27.678761v1

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Reposted by Enrica Boda & team

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 11d

Cortical myelination networks reflect neuronal gene expression and track adolescent age in marmosets https://www.biorxiv.org/content/10.1101/2025.09.26.678906v1

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Reposted by Enrica Boda & team

Gregory MS @gregory-ms.com · 12d

Multiple sclerosis is a chronic, immune-mediated neurodegenerative disorder of the central nervous system. Oligodendrocyte dysfunction contributes to the failure of remyelination observed in chronic multiple sclerosis lesions. Key factor...
#MSchat #MS #Neurology #MultipleSclerosis #NeuroSky #MedSky

White Matter in Crisis: Oligodendrocytes and the Pathophysiology of Multiple Sclerosis

Multiple sclerosis is a chronic, immune-mediated neurodegenerative disorder of the central nervous system. Oligodendrocyte dysfunction contributes to the failure of remyelination observed in chronic m

gregory-ms.com

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Reposted by Enrica Boda & team

Zoltan Molnar @zoltan-molnar.bsky.social · 12d

CORTICAL EVOLUTION - 15-17th June 2026 - Bilbao Spain
Organizers: Verónica Martínez Cerdeño, Fernando García Moreno, Elena Vecino, and Stephen Noctor
Early registration until 1st May 2026
ventricular.org/corticalevol...
@veronicamartinez.bsky.social @phylobrain.bsky.social

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Reposted by Enrica Boda & team

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 14d

Progenitor Timing Shapes NG2-Glia Fate and Oligodendrocyte Differentiation https://www.biorxiv.org/content/10.1101/2025.09.24.678191v1

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Reposted by Enrica Boda & team

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 17d

Oligodendrocyte progenitor cell responses to inflammatory demyelination with aging https://www.biorxiv.org/content/10.1101/2025.09.22.677854v1

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Reposted by Enrica Boda & team

Adrian Liston @labliston.bsky.social · 20d

Over the last 8 years, Oliver Burton has tested >1000 different fix/perm combos, and here the final verdict is: "Burton's Best Buffer": 2% formalin, 0.05% Fairy dish soap, 0.5% Tween-20, 0.1% Triton X-100.

Yep, replace all of those expensive detergents with @pg.com dishwashing liquid

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Reposted by Enrica Boda & team

Adrian Liston @labliston.bsky.social · Sep 3

🧵How to write and manage your first research budgets

The point of funding is to convert it into quality research. A well-spent research budget should fund the idea it was raised on, plus revision experiments, plus preliminary data for the next grant. So you need to spend, while avoiding waste.

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Reposted by Enrica Boda & team

Giorgio Vallortigara @gvallortigara.bsky.social · 19d

en.ilsole24ore.com/art/by-vallo...
Marsilio Editori

From Vallortigara a metaphysical thriller on the capacity to consolidate memories

The neuroresearcher and well-known essayist makes his debut with his first novel, 'Desiderare'. In the background, studies on the nature of memory and consciousness

en.ilsole24ore.com

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Reposted by Enrica Boda & team

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 20d

Temporal Requirement for Stearoyl-CoA Desaturase 1 in Oligodendrocyte Development but Not Myelin Maintenance https://www.biorxiv.org/content/10.1101/2025.09.18.676928v1

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Reposted by Enrica Boda & team

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 22d

Patient-derived lymphocytes drive smoldering lesion pathology in a chimeric multiple sclerosis mouse model https://www.biorxiv.org/content/10.1101/2025.09.16.676229v1

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Reposted by Enrica Boda & team

Institute for Stroke and Dementia Research (ISD) @isd-research.bsky.social · 24d

Cortical tau deposition promotes atrophy in connected white matter regions in Alzheimer’s disease url: academic.oup.com/brain/articl...
#tao @nfranzme.bsky.social

Cortical tau deposition promotes atrophy in connected white matter regions in Alzheimer’s disease

In Alzheimer’s disease, tau pathology not only contributes to cortical atrophy but also leads to the degeneration of white matter tracts that connect diffe

academic.oup.com

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Reposted by Enrica Boda & team

Joe Sabatino @jsabatino37.bsky.social · 23d

Very pleased to publish this new review with Farah Wahbeh on the role of #EBV in #Multiplesclerosis. I learned a lot writing this, I hope others find it useful too

www.neurology.org/doi/10.1212/...

Epstein-Barr Virus in Multiple Sclerosis | Neurology Neuroimmunology & Neuroinflammation

Epstein-Barr virus (EBV) is a very common herpesvirus that infects more than 90% of the general population. Epidemiologic data indicate that EBV is a requisite risk factor for the development of multi...

www.neurology.org

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Reposted by Enrica Boda & team

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 23d

Developmental Connectomics of the Mouse Cerebellum https://www.biorxiv.org/content/10.1101/2025.09.15.676403v1

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Reposted by Enrica Boda & team

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 23d

Spatial transcriptomics of compartmentalised inflammation in a natural disease multiple sclerosis cohort. https://www.biorxiv.org/content/10.1101/2025.09.10.675210v1

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Enrica Boda & team @enricaboda-team.bsky.social · 24d

Super!

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 24d

Imaging progenitor cell differentiation during central nervous system remyelination using an MRI gene reporter https://www.biorxiv.org/content/10.1101/2025.09.10.674209v1

Reposted by Enrica Boda & team

Neurofrontiers @neuro-frontiers.bsky.social · 25d

We’ve known for some time that air #pollution is bad for human #health. But the focus was mostly on the lungs and heart. Yet somewhere along the way, it became more mainstream to consider how air pollution might affects brains too. What I found surprising was the recency of that.
#neuroskyence

How does air pollution impact your brain? - Neurofrontiers

Air pollution is increasingly recognized as having negative effects on brain health. Here we take a look at what those are.

neurofrontiers.blog

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Reposted by Enrica Boda & team

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 25d

Dual role of GABAB receptor in oligodendrocyte function and immune modulation in experimental multiple sclerosis https://www.biorxiv.org/content/10.1101/2025.09.09.675094v1

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Reposted by Enrica Boda & team

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 26d

Erythropoietin alleviates intellectual disability and autism-like behavior of mice caused by Zbtb20 haploinsufficiency, a construct-valid model of Primrose syndrome https://www.biorxiv.org/content/10.1101/2025.09.11.675680v1

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