Eric Horvitz
@erichorvitz.bsky.social
2.6K followers 170 following 29 posts
Chief Scientific Officer of Microsoft.
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erichorvitz.bsky.social
How do we decide what not to share?
I explore “information hazards” in this blog--on when openness in science risks misuse. Paraphrase effort led to a first-of-its-kind publishing model, accepted by Science: "When AI Meets Biology" aka.ms/AAy56z3 Full paper on the project avail here: aka.ms/AAy5e9c
The Paraphrase Project
Strengthening nucleic acid biosecurity screening against generative protein design tools — improving hazard detection in the age of AI-assisted protein engineering.
aka.ms
erichorvitz.bsky.social
Background and resources on the Paraphrase Project, published in Science last week, with some of the behind-the-scenes story, my blog on the disclosure dilemma, and a conversation with Bruce Wittman, Tessa Alexanian, and James Diggans. @msftresearch.bsky.social

Full paper at: aka.ms/AAy5e9c
Reposted by Eric Horvitz
besmiranushi.bsky.social
Federal research funding works. It’s not an expense–it’s an investment. It’s not overhead–it’s a down payment on the future. - Eric Horvitz, Margaret Martonosi, Moshe Y. Vardi, and James Larus in CACM cacm.acm.org/opinion/keep... @erichorvitz.bsky.social
Keeping the Dream Alive: The Power and Promise of Federally Funded Research – Communications of the ACM
cacm.acm.org
erichorvitz.bsky.social
Study on clinician-AI collaboration: "As LLMs now demonstrate expert-level diagnostic performance, the focus shifts from whether AI can offer valuable suggestions to how it can be effectively integrated into the diagnostic workflow..." Many opportunities ahead.

www.medrxiv.org/content/10.1...
erichorvitz.bsky.social
I’m looking forward to the 2025 RAISE Health Symposium at Stanford University, hosted by @stanfordmedicine.bsky.social and the @stanfordhai.bsky.social. Symposium explores the today's health AI, what’s coming next, and directions forward. More here: med.stanford.edu/raisehealth/...
erichorvitz.bsky.social
Conversation with the Computer History Museum on the trajectory of AI through time, on where we are today, and on directions heading into the future. www.youtube.com/watch?v=ddjN...
@computerhistory.bsky.social
Chatbots Decoded Interview: Eric Horvitz
YouTube video by Computer History Museum
www.youtube.com
erichorvitz.bsky.social
Code avail for paper, "Improving Instruction-Following in Language Models through Activation Steering" at #ICLR2025. Exciting to see influence of computed vectors across models.
Paper: arxiv.org/abs/2410.12877
Repo: github.com/microsoft/ll...
@alestolfo.bsky.social @besmiranushi.bsky.social
erichorvitz.bsky.social
Just released: Report of the 2025 AAAI Presidential Panel on the Future of AI Research. Covers a selection of topics of a larger set of research directions, providing high-level glimpses. Enjoyed collaborating with colleagues on the project. Report pdf avail here:
aaai.org/wp-content/u...
erichorvitz.bsky.social
Background on our quantum computing announcement this week on progress on developing a topologically protected qubit: Here's an open version of my LinkedIn article on the nearly two-decade--long project: aka.ms/quantum_brea...
https://aka.ms/quantum_breakthrough
t.co
erichorvitz.bsky.social
MedHELM announced: Popular benchmarks for medical challenge problems have become saturated w/ high perf. of LLMs. New set of benchmarks for evaluating performance LLMs in medicine. 31 datasets, clinically relevant tasks covering 22 subcategories.

Leaderboard: lnkd.in/gZ7CkNqc
Blog: lnkd.in/gsVQUc2P
Holistic Evaluation of Language Models (HELM)
lnkd.in
erichorvitz.bsky.social
Meeting at Asilomar 50 yrs after 1975 meeting. New issues today with fast-paced advances of AI & biology--and timeless pursuit of questions & directions on the responsibilities of scientific community. Important conversations in a beautiful setting.

NPR coverage: www.npr.org/2025/02/25/n...
erichorvitz.bsky.social
Great way to catch up with colleagues on the latest innovations in AI: Poster sessions! At annual meeting of the Association for the Advancement of Artificial Intelligence (AAAI) in Philadelphia.
erichorvitz.bsky.social
When science & technology transcend politics: At Senate Committee hearing, Senators Maria Cantwell & Ted Cruz joined hands to showcase Microsoft’s new quantum chip that leverages discoveries at the frontiers of physics. A striking bipartisan moment. More on quantum effort: aka.ms/quantum_brea...
erichorvitz.bsky.social
Surprising scene: Jug of spilled milk in front of exhibition hall at NeurIPS meeting. Great catching up with John Platt as the anomalous event unfolded. We both had our assistants at the ready.
Reposted by Eric Horvitz
franknoe.bsky.social
Super excited to preprint our work on developing a Biomolecular Emulator (BioEmu): Scalable emulation of protein equilibrium ensembles with generative deep learning from @msftresearch.bsky.social ch AI for Science.

www.biorxiv.org/content/10.1...
erichorvitz.bsky.social
Processes for seeking mutual understanding or “grounding,” adapted from psychology, are important in designs for agentic AI systems, per their complexity & potential high stakes of actions taken on behalf of users. New position paper with colleagues: tinyurl.com/mr2jr2rx @msftresearch.bsky.social
Challenges in Human-Agent Communication - Microsoft Research
Explore key challenges in human-agent communication with generative AI and autonomous agents. Learn about transparency, control, and challenges for improving human-AI interaction.
tinyurl.com