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Eric Topol

@erictopol.bsky.social

140K followers 310 following 2.6K posts

physician-scientist, author, editor https://www.scripps.edu/faculty/topol/ Ground Truths https://erictopol.substack.com SUPER AGERS https://www.simonandschuster.com/books/Super-Agers/Eric-Topol/9781668067666

www.scripps.edu

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Eric Topol @erictopol.bsky.social · May 27

A new cover for SUPER AGERS after making the NYT bestseller list. Thanks to you for making it the #1 ranked new non-fiction book on Amazon.
amazon.com/gp/new-relea...

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Eric Topol @erictopol.bsky.social · 23h

www.washingtonpost.com/opinions/202...

Opinion | Six surgeons general: It’s our duty to warn the nation about RFK Jr.

We took an oath to declare dangers when we found them. We’re doing that again today.

www.washingtonpost.com

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Eric Topol @erictopol.bsky.social · 1d

"Anyone who is interested in the current and future states of healthspan treatments can appreciate......"—Prof @ctmurphy1.bsky.social @nature.com
www.nature.com/articles/d41...

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Eric Topol @erictopol.bsky.social · 1d

Exercising fathers, enhanced endurance and metabolic heath in offspring, through sperm microRNAs (as demonstrated in mice)
www.cell.com/cell-metabol...

Paternal exercise confers endurance capacity to offspring through sperm microRNAs

Yin et al. show that paternal exercise improves offspring endurance capacity and metabolic health via sperm microRNAs that reprogram gene expression in early embryos, revealing how exercise benefits c...

www.cell.com

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Eric Topol @erictopol.bsky.social · 5d

How exercise promotes the immune system vs cancer, working through a gut bacteria metabolite
www.cell.com/cell/abstrac...

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Eric Topol @erictopol.bsky.social · 5d

A.I. generated clinic notes from ambient out-patient visits helps clinicians in many ways, across 6 health systems jamanetwork.com/journals/jam...

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Eric Topol @erictopol.bsky.social · 5d

New @nature.com
www.nature.com/articles/d41...

Exclusive: ex-CDC director talks about why she was fired

“I would never do that, as a scientist,” Susan Monarez says of being asked to approve changes to vaccine recommendations without knowing the details.

www.nature.com

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Eric Topol @erictopol.bsky.social · 6d

The Cassandra Curse
Ground Truths newsletters and podcasts are all free with NO ads. Subscribe erictopol.substack.com

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Eric Topol @erictopol.bsky.social · 6d

The role of perturbation of our circadian clock plays in promoting the fibrosis (scarring) of organs
www.jci.org/articles/vie...

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Eric Topol @erictopol.bsky.social · 6d

www.freethink.com/biotech/eric...

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Eric Topol @erictopol.bsky.social · 6d

Evidence keeps accumulating for the environmental toxin exposure link to Parkinson's disease, beyond pesticides. Today on trichloroethylene (TCE), used in dry cleaning
www.neurology.org/doi/10.1212/...

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Eric Topol @erictopol.bsky.social · 6d

My conversation today with @drtomfrieden.bsky.social, Former CDC Director, on his new book THE FORMULA and our current state of affairs in US public health
erictopol.substack.com/p/tom-friede...

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Reposted by Eric Topol

Eric Topol @erictopol.bsky.social · 7d

Children and teens who had a Covid reinfection had a doubling of #LongCovid risk (PASC) and a significant increase in many other adverse outcomes (Figure) www.thelancet.com/journals/lan...

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Eric Topol @erictopol.bsky.social · 6d

Our capability to prevent diseases from occurring is gaining momentum. Using A.I. to predict >1,200 diseases 20 years ahead adds to the ways we'll be able to achieve primary prevention.
nature.com/articles/d41...
erictopol.substack.com/p/dawn-of-a-...

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Eric Topol @erictopol.bsky.social · 6d

Chronic poor sleep quality, inflammation, and accelerating brain aging (BAG=brain age gap)
www.thelancet.com/journals/ebi...

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Eric Topol @erictopol.bsky.social · 7d

Agree!

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Eric Topol @erictopol.bsky.social · 7d

The accompanying editorial tells the sad truth that is largely being ignored
www.thelancet.com/journals/lan...

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Eric Topol @erictopol.bsky.social · 7d

Children and teens who had a Covid reinfection had a doubling of #LongCovid risk (PASC) and a significant increase in many other adverse outcomes (Figure) www.thelancet.com/journals/lan...

15 290 490

Eric Topol @erictopol.bsky.social · 7d

Thanks for the clarification, Hank. This paragraph in the Discussion led to me buy into functionality of the cells

Eric Topol @erictopol.bsky.social · 7d

www.nature.com/articles/s41...

Limited overlap between genetic effects on disease susceptibility and disease survival - Nature Genetics

Systematic comparison of genome-wide association results for disease risk and disease-specific mortality for nine common diseases across seven biobanks finds limited overlap between genetic effects on disease susceptibility and survival.

www.nature.com

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Eric Topol @erictopol.bsky.social · 7d

A person's genetics has a role in susceptibility to many diseases (Figure), but has little correlation with how the disease may progress or lead to a fatal outcome.
nature.com/articles/s4158

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Eric Topol @erictopol.bsky.social · 7d

The process of mitomeiosis

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Eric Topol @erictopol.bsky.social · 7d

Not every day a skin cell is turned into viable egg!
www.nature.com/articles/s41...

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Eric Topol @erictopol.bsky.social · 7d

Sleep regularity (SRI) is critical...take a look at the broad impact of keeping on a schedule (Figure 3.9, SUPER AGERS) (the higher the regularity, the better the outcomes)

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Eric Topol @erictopol.bsky.social · 7d

Evidence-based tips on getting better sleep: the primacy of circadian rhythm
new feature
@nature.com
nature.com/articles/d41...

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Eric Topol @erictopol.bsky.social · 8d

This is a key step towards primary prevention of cardiovascular disease, one of the big 3 age-related diseases that we should prevent from ever occurring.
More here erictopol.substack.com/p/dawn-of-a-...

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