Erik van Zwet
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erik-van-zwet.bsky.social
Erik van Zwet
@erik-van-zwet.bsky.social
Statistician at the Leiden University Medical Center in the Netherlands.
How come my comment doesn't appear?
December 9, 2025 at 6:27 PM
Harassing reviewers is actually not a normal part of science. In any case, I commented on your blog post.
December 9, 2025 at 9:03 AM
I had plenty of criticism when I reviewed your paper, but then you started harassing me until Daniel told you to stop it.
December 8, 2025 at 6:33 PM
At least not for you.
December 8, 2025 at 4:45 PM
It's the exact same thing with you and Daniel: I try to have a discussion about statistical methods, but I just get accusations and insults.
December 8, 2025 at 8:45 AM
As a scientist you should be concerned when your model conflicts with reality (in this case: there is no publication bias against significant clinical trials). You prefer to shoot the messenger.
December 8, 2025 at 8:44 AM
EITHER you proved that there is a strong publication bias *against* significant clinical trials OR there is a problem with your method. The former is ridiculous, but you won't even consider the latter.
December 8, 2025 at 8:44 AM
I'm pointing out a glaring problem with your z-curve method, and all you have to say is "do better"?
December 8, 2025 at 8:43 AM
December 7, 2025 at 9:14 PM
Despite n=41279, the estimated distribution of |z| between 0 and 1.96 is *completely* wrong. How reliable do you think the estimate is in a typical meta-analysis?
December 7, 2025 at 9:13 PM
Here z-curve estimates that non-significant clinical trials are 1.66 times *more* likely to be published than significant ones. The "confidence interval" is 1.17 to 2.45. replicationindex.com/2020/12/24/i...
Ioannidis is Wrong Most of the Time - Replicability-Index
John P. A. Ioannidis is a rock star in the world of science (wikipedia). By traditional standards of science, he is one of the most prolific and influential scientists alive. He has published over 1,0...
replicationindex.com
December 7, 2025 at 6:05 PM
Hi Ben - I wrote that post. If you put your questions and comments at statmodeling, I'd be happy to respond there so that others can see!
November 16, 2025 at 12:40 PM
Axioms don't have proofs.
October 23, 2025 at 2:43 PM
Thanks for the nice blog post about our paper! I'll just add that our shrinkage estimator is a little bit ad hoc, but we did evaluate its performance: onlinelibrary.wiley.com/doi/full/10....
Evaluating a shrinkage estimator for the treatment effect in clinical trials
The main objective of most clinical trials is to estimate the effect of some treatment compared to a control condition. We define the signal-to-noise ratio (SNR) as the ratio of the true treatment ef...
onlinelibrary.wiley.com
August 11, 2025 at 10:36 AM
Hmm, I get 2x38 for 90% power of a two-sided test at level 10%. But nevermind. I came here to advertize an app which calculates the gain in power if you don't dichotomize. In this case, they would have needed only 2x19. The app is here: vanzwet.shinyapps.io/info_loss/
May 8, 2025 at 5:21 PM