Lung cancer mortality can be lowered through early-diagnostic screening of people demonstrating a ≥1.5 % 6-year risk of tumor development. However, ma…

Signal Transduction and Targeted Therapy - Rapid amyloid-β clearance and cognitive recovery through multivalent modulation of blood–brain barrier transport

YouTube video by DoktorWeigl

Rochester General Hospital, the University of Texas Southwestern Medical Center, and Aga Khan University report that applying newer cardiovascular risk equations could sharply reduce the number of mid...

Unwell with a bad throat and temperature? You may have one of the new Covid strains circulating this autumn.

acute-toxicity-and-hypolipidemic-activities-of-clove-and-ginger-extract

In many countries, a large majority of adults consume caffeine daily. This review summarizes the evidence about the varied physiological effects of caffeine and coffee and the risks of cardiovascul...

In brief, Santos-Pujol and colleagues characterize the multiomics landscape of the human with the most extreme longevity. The study enables the association of advantageous genetic variants, an engaged...

BACKGROUND: The incidence of postural orthostatic tachycardia syndrome (POTS) in long COVID has been a growing concern since the first cases were reported in 2021. The aim of this study was to assess ...

Rochester General Hospital, the University of Texas Southwestern Medical Center, and Aga Khan University report that applying newer cardiovascular risk equations could sharply reduce the number of mid...

BackgroundThere is indirect evidence that inhaled traffic-related particulate matter (PM) penetrates into the human circulation. Since nanoparticles readily adhere to red blood cells (RBCs) in vitro, we sought to determine whether a mechanism of systemic transport of translocated traffic-related particles is via adherence to RBCs in vivo.MethodsAdult volunteers were exposed to traffic-related emissions from a main road for 1 h. Volunteers were also exposed to emissions wearing a FFP2 mask. Exposure to black carbon PM was assessed by portable aethalometer. The mean area (μm2) of adherent black PM per RBC was determined from unstained blood smears from 3000 cells by light microscopy. Particle composition was determined by scanning transmission electron microscopy and energy dispersive x-ray analyses. The capacity of diesel exhaust particles (DEP) to adhere to human RBCs in vitro was determined, and RBCs were examined after intratracheal instillation of DEP to a mouse model.ResultsExposure to traffic-related emissions increased personal black carbon PM (n=12, p=0.001 vs. baseline). Exposure increased the area of particles adherent to RBCs (p<0.001 versus baseline), and this was reduced by wearing a FFP2 mask (p=0.002 versus no mask). Traffic exposure increased the abundance of metal-bearing nanoparticles associated with RBCs. Diesel exhaust particles adhered to RBCs in vitro in a dose-dependent manner. Particles were found adherent to circulating RBCs after intratracheal diesel exhaust particles.ConclusionAdhesion of traffic-related PM to RBCs is a systemic transport mechanism. Quantification of particles on RBCs is a putative practical biomarker of inhaled dose.

These findings suggest that IAV infections enhance the systemic propensity for NETosis and foster a procoagulant state, thereby increasing the risk of cerebral damage and thrombosis following stroke. ...

This study assesses the association between cardiorespiratory fitness and long-term mortality in adults undergoing exercise treadmill testing.

Unwell with a bad throat and temperature? You may have one of the new Covid strains circulating this autumn.

YouTube video by Patrick recherchiert

Mehr als sieben Millionen Menschen sollen zuletzt in Deutschland an Atemwegserkrankungen gelitten haben – Tendenz steigend. Auch die Covid-Fälle nehmen wieder zu.

This study assesses the association between cardiorespiratory fitness and long-term mortality in adults undergoing exercise treadmill testing.

Cold and Hot Consumption and Health Outcomes Among U.S. Asian and White Populations

Poor sleep health may accelerate brain ageing. This may be driven by higher levels of systemic inflammation.

Dr. Steven Austad said many longevity trends have dubious claims behind them. He mainly focuses on his diet and exercise routine.

Instead of boarding a plane, a man has to go to A&E because he can't get his Galaxy ring off his finger at the airport security check.

Does walking influence how people process sensory information, like sounds, from the environment? In a new JNeurosci paper, researchers led by Liyu Cao, from Zhejiang University, and Barbara Händel, f...

The human body requires protein as one of its fundamental nutritional elements, and it is known as the 'building block of the body.' The body depends on protein to construct and restore muscles, as we...

Inhaled heparin significantly lowers the risk of death and ventilation in COVID-19 patients while also showing potential against other respiratory infections. With its unique triple-action benefits, i...

Apfelessig wird in Social Media immer wieder als Wundermittel beim Abnehmen verkauft. Doch die Studie, auf die sich viele berufen, weist zahlreiche Mängel auf