FEBS Letters
@febsletters.bsky.social
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Publishing cutting-edge reports in Biochemistry, Structural Biology, Molecular Cell Biology, Biophysics, Systems Biology, Microbiology and more. Part of @febspress.bsky.social. febsletters.org
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🔔 Issue 18 of FEBS Letters features articles on #photoreceptors, #immunology, and more, including:

👁️ Perspective: cGMP and cAMP systems in #RetinitisPigmentosa
🧬 In a Nutshell: #mRNA metabolism in immune cells
🫧 Editor's Choice: Genomic modifiers of #NiemannPick severity

➡️ bit.ly/4mIaSQE
febsletters.bsky.social
From lactation to malignancy: a new study by Pietro Ancona et al. reveals new insights into #breastcancer through comparison of healthy and cancerous breast gland at single-cell resolution.
Read the full article here ➡️ tinyurl.com/bdcd4c7v
febsletters.bsky.social
Gcn2 phosphorylates #eIF2α in response to amino acid starvation. In a new study published in FEBS Letters, Bianca J. M. Sansom et al. uncover how Yih1/IMPACT inhibits #Gcn2
Read online here➡️ tinyurl.com/ycymxch9
#proteinsynthesis
febsletters.bsky.social
How does the multispecific #antibody G2 bind to different #peptides? 🤔 Nobutoshi Ito, Masayuki Oda, et al. answer this question in this new article in FEBS Letters➡️ tinyurl.com/jxzefyxd
febsletters.bsky.social
The #chelatase activity of magnesium dechelatase is associated with #chlorophyll degradation.
Read the full article here ➡️ doi.org/p7td
febsletters.bsky.social
🧬 Our most recent Editor's Choice article by Andrés D. Klein et al. report genomic modifiers of neurological resilience to #NiemannPick type C disease, a lysosomal storage disorder

➡️ doi.org/10.1002/1873-3468.70091

#Mitochondria #Biomarkers
febsletters.bsky.social
#ERBIN is a key suppressor of #EMT through coordinated inhibition of TGF-β and EGFR signaling pathways.

Read the full article here ➡️ tinyurl.com/43z64k43
febsletters.bsky.social
🔔 Issue 18 of FEBS Letters features articles on #photoreceptors, #immunology, and more, including:

👁️ Perspective: cGMP and cAMP systems in #RetinitisPigmentosa
🧬 In a Nutshell: #mRNA metabolism in immune cells
🫧 Editor's Choice: Genomic modifiers of #NiemannPick severity

➡️ bit.ly/4mIaSQE
febsletters.bsky.social
🌟Elin Zätterman🌟(University of Dundee, Scotland) won a FEBS Letters #PosterPrize at the EMBO/FEBS Lecture Course 'Susan Lindquist School on #Proteostasis, held in Espoo, Finland!

🎉🏅Congratulations, Elin! 🎉👏👏👏

📸Photo: Elin with our Managing Editor, Dr. Duncan Wright.

#EMBOFEBSproteostasis
febsletters.bsky.social
🎉🏅We congratulate 🌟Megan Lee 🌟 @eawag.bsky.social, winner of the FEBS Letters #PosterPrize at the EMBO/FEBS Lecture Course 'The New #Microbiology', recently held in Spetses, Greece! 🎉👏👏👏

#EMBOnewMicrobiology
febsletters.bsky.social
Looking to create an eye-catching #graphicalabstract to summarise your research? 🎨 Scientist and graphic designer Dr. Matteo Oliverio shares his tips and experience in this new guide published in @febsletters.bsky.social
Read the full article here ➡️ tiny.cc/1pqs001 #sciencecommunication
Image depicting elements of graphical abstracts discussed in this article, presented as eight segments of a square: layout, colour, text, lines, the "sciency" touches, tools, AI, and proof-reading.
febsletters.bsky.social
We're here for Day 3 of the Susan Lindquist School on Proteostasis! This has been a fantastic course, with talks on both the history of the field and the latest research, as well as many animated discussions--and there's much more yet! #ProteostasisSchool #Proteostasis #embofebsproteostasis
febsletters.bsky.social
🎉🏅We congratulate 🌟Nils Reinhard 🌟 (University of Würzburg, Germany), winner of a FEBS Letters #PosterPrize at the European Biological Rhythms Society meeting #EBRS2025 in Lübeck, Germany! 🎉👏👏👏

@nils-reinhard.bsky.social
febsletters.bsky.social
🎉🌟Ruoshi Li (University of Tsukuba, Japan) won a FEBS Letters #PosterPrize at the European Biological Rhythms Society meeting #EBRS2025 in Lübeck, Germany!

🏅Congratulations, Ruoshi! 🎉👏👏👏

#circadian
febsletters.bsky.social
Very excited to be attending the fourth Susan Lindquist School on Proteostasis in Espoo, Finland! We enjoyed fantastic talks by Rick Morimoto, David Balchin, and Anne Bertolotti on the first day, and were happy to contribute to a discussion on academic publishing.
#embofebsproteostasis
febsletters.bsky.social
Bacterial GES-1 is an extended-spectrum β-#lactamase conferring #AntimicrobialResistance.
Find out how it is inhibited by the β-lactamase inhibitors enmetazobactam and tazobactam

🖊️ Adrian Mulholland, James Spencer (University of Bristol) & colleagues

➡️ bit.ly/4n6AFmw
febsletters.bsky.social
🎉🎖️We congratulate 🌟Julia Scott🌟(Center for Molecular Medicine, UMC Utrecht, the Netherlands), on winning the FEBS Letters #PosterPrize at the FEBS Advanced Lecture Course 'Functional #genomics of #metabolic diseases', held in Spetses, Greece! 🎉👏👏👏

@juliasscott.bsky.social
febsletters.bsky.social
⏰ Nobel laureate Aziz Sancar reviews the molecular clock: how protein interactions & modifications drive circadian rhythms, with links to health & disease.
Read more: febs.onlinelibrary.wiley.com/doi/10.1002/...
#CircadianRhythms #MolecularBiology #clock
febsletters.bsky.social
🔔 New Issue!

🩻 Articles on the #cytoskeleton and more, including:

🥇 Editor's Choice: β-#Actin mutation impairs SETD3-mediated methylation
🖊️ Review: Mechanisms of #GPCR anterograde transport
🧑‍🔬 Scientists' Forum: Building a new research group

➡️ bit.ly/47IrzHP
febsletters.bsky.social
How do lipid-modified proteins reach the cilium? 🧬 ARL3 and its regulators create spatial control of cargo release—key to signaling & linked to ciliopathies like Joubert syndrome.
Read more: febs.onlinelibrary.wiley.com/doi/10.1002/...
#CellBiology #Cilia #GTPases
febsletters.bsky.social
🔬 Why does cancer relapse years after treatment? Dormancy, aided by autophagy, helps tumors survive, hide & later reactivate.
Explore the autophagy–dormancy link: febs.onlinelibrary.wiley.com/doi/10.1002/...
#CancerResearch #Autophagy #Metastasis
febsletters.bsky.social
🎉 We also congratulate two runners-up, whose essays will be published later this year:

Dr. Cara Giovanetti, "It Takes a Village: Preparing #WomenInScience for difficult times"

Mahaiwon Shadang, "The Other Women"

Thank you to every researcher who submitted!

@idontevencara.bsky.social
febsletters.bsky.social
All aerobic life depends on pyruvate dehydrogenase complexes ⚡ Yet their structures and assembly vary widely across species. Discover the differences: febs.onlinelibrary.wiley.com/doi/10.1002/...
#Biochemistry #Metabolism #MolecularBiology
febsletters.bsky.social
🥇👩‍🔬 Congratulations to Rayane da Cruz Albino winner of our 2025 Writing Contest: Celebrating #WomenInScience! 🎊

Her essay, “Black Pitch Illuminated: The legacy of Professor Jean H. Langenheim,” celebrates a trailblazer who inspired Albino’s own journey in ethnobotany.

➡️ bit.ly/3I21s3U

#WomenInSTEM
febsletters.bsky.social
To survive multiple extreme conditions, polyextremophiles produce protective exopolysaccharides 🛡️Learn how these molecules aid adaptation: febs.onlinelibrary.wiley.com/doi/10.1002/...
#Microbiology #Extremophiles #Glycobiology
febsletters.bsky.social
🔔 New Issue: Focus on #Autophagy and #Cancer, featuring three new Reviews:

🖊️ Transcriptional regulation of autophagy in cancer
🖊️ Autophagy in cancer, liver and brain disorders
🖊️ Autophagy and cancer dormancy

Plus Research articles on both iron #metabolism and #microbiology:

➡️ bit.ly/3VlJBYJ