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frankiedheyward.bsky.social
Frankie D Heyward
@frankiedheyward.bsky.social
380 followers 1.9K following 1 posts
Assistant Professor @ UT Southwestern PI of Heyward Nutritional & Behavioral Epigenetics Lab (https://www.frankieheywardlab.com/) Broadly Studying: The Epigenetic Control of Appetite 🧠🧬🍔🤤
www.frankieheywardlab.com
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frankiedheyward.bsky.social
Frankie D Heyward @frankiedheyward.bsky.social · 3h
I’m excited to share our new preprint! We built a single-nucleus multiomic (snRNA-seq+snATAC-seq) atlas of leptin receptor-expressing hypothalamic neurons (LepRᴴʸᵖᵒ) and identified conserved cis-regulatory elements overlapping human obesity-linked variants and eQTLs🧠🧬
www.biorxiv.org/content/10.1...
Single-nucleus transcriptional and chromatin accessibility profiling of mouse hypothalamic LepRb neurons reveals cell type-specific cis-regulatory elements linked to human obesity
Leptin receptor-expressing hypothalamic neurons (LepRHypo) are key regulators of energy balance, yet a comprehensive, cell type-resolved, chromatin accessibility map of these neurons is lacking. We pr...
www.biorxiv.org
4 10
frankiedheyward.bsky.social
Frankie D Heyward @frankiedheyward.bsky.social · 3h
I’m excited to share our new preprint! We built a single-nucleus multiomic (snRNA-seq+snATAC-seq) atlas of leptin receptor-expressing hypothalamic neurons (LepRᴴʸᵖᵒ) and identified conserved cis-regulatory elements overlapping human obesity-linked variants and eQTLs🧠🧬
www.biorxiv.org/content/10.1...
Single-nucleus transcriptional and chromatin accessibility profiling of mouse hypothalamic LepRb neurons reveals cell type-specific cis-regulatory elements linked to human obesity
Leptin receptor-expressing hypothalamic neurons (LepRHypo) are key regulators of energy balance, yet a comprehensive, cell type-resolved, chromatin accessibility map of these neurons is lacking. We pr...
www.biorxiv.org
4 10