Frédéric Guillaume
fredguillaume.bsky.social
Frédéric Guillaume
@fredguillaume.bsky.social
Evolutionary Biologist | Prof | Head of Department | University of Helsinki | Finland | Developer of Nemo
Loves bugs when they crawl in a pot of flour. Hate bugs when they cripple my code.
lesson #1 bsky doesn't like PNG files with a transparent background!!!
reposting it here
December 10, 2025 at 10:15 AM
Contrary to usual expectation of stronger stabilising selection on central, more connected genes in gene expression networks, we found that hub genes responded more to selection. Hub genes were under stronger indirect selection than non hub genes and showed stronger signals of selection at SNP level
December 10, 2025 at 10:06 AM
The quantitative genetics approach allowed us to predict evolutionary changes in gene expression at the whole transcriptome level.

With experimental evolution of replicated lines in a stressful hot and dry environment, we could verify that gene expression evolved as predicted after 20 generations.
December 10, 2025 at 10:06 AM