Gabriel da Silva
banner
gabriel93dasilva.bsky.social
Gabriel da Silva
@gabriel93dasilva.bsky.social
I am trilled to share my latest publication where we contribute to the knowledge of how ATR kinase, a DNA damage response factor, modulates DNA replication timing during stress in Leishmania major.

Huge thanks to @rmc9z.bsky.social, @LuizTosi and the collaborators for the support and guidance!
ATR, a DNA damage kinase, modulates DNA replication timing in Leishmania major
Author summary A series of protein kinases act at the pinnacle of eukaryotic cells’ DNA damage response, organising and guiding repair. One such kinase is ATR, which recognises single-stranded DNA for...
dx.plos.org
December 8, 2025 at 10:41 AM
Reposted by Gabriel da Silva
Pleased 2 share our new article: single-molecule replication mapping in Leishmania using DNAscent.
We show widespread stochastic origin firing and insights into genome variability.

www.cell.com/cell-reports...
August 6, 2025 at 8:20 AM
Reposted by Gabriel da Silva
Aargh, proper link to pre-print (hopefully!)

doi.org/10.1101/2025...
January 14, 2025 at 9:01 PM