gearseminar.bsky.social
GEARs
@gearseminar.bsky.social
34 followers 17 following 2 posts
Gene expression and RNA Seminar Series in Boston area!
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Reposted by GEARs
baluapuri.bsky.social
Apoorva Baluapuri @baluapuri.bsky.social · Jun 20
Much appreciate the spotlight on our (‪@adelmanlab.bsky.social‬) paper about INT depletion/dsRNA-induced stress responses by @hanzlikovalab.bsky.social Amazing to see the finding being placed in perspective of the big picture of neurodevelopmental diseases and therapeutic targets 🙏 #RNABiology
cp-molcell.bsky.social
Molecular Cell @cp-molcell.bsky.social · Jun 20
Integrator complex collapse: A mechanistic route to integrated stress response and disease
Integrator complex collapse: A mechanistic route to integrated stress response and disease
In a recent Cell article, Baluapuri et al. show that loss of the Integrator (INT) complex activates the integrated stress response via double-stranded RNA from incomplete pre-mRNAs, revealing a link to INT-related neurodevelopmental diseases and potential therapeutic targets.
dlvr.it
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Reposted by GEARs
fnucleosome.bsky.social
FragileNucleosome @fnucleosome.bsky.social · May 15
Join us on Wednesday next week for two exciting talks on transcription regulation from @kasitc.bsky.social and @davidsuter.bsky.social!

You can register at: us06web.zoom.us/webinar/regi...
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Reposted by GEARs
lucas.farnunglab.com
Lucas Farnung @lucas.farnunglab.com · May 6
Outstanding work from Allison James who will graduate next month! If you like our work, consider applying to the Farnung Lab. More info: farnunglab.com
Farnung Lab
farnunglab.com
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Reposted by GEARs
lucas.farnunglab.com
Lucas Farnung @lucas.farnunglab.com · May 6

🧬🎉Thrilled to share our new chromatin remodeling study! We reveal three states of human CHD1 and identify a novel "anchor element" that interacts with the acidic patch—conserved among remodelers. Our structures clarify mechanisms of remodeler recruitment! Link: authors.elsevier.com/a/1l2ik3vVUP...
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gearseminar.bsky.social
GEARs @gearseminar.bsky.social · May 1
Excited to see everyone tonight at Whitehead Institute for the 2nd GEARS seminar, featuring three talks from Harleen Saini, Vikram Agarwal, and Ava Carter!
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Reposted by GEARs
xiaoliwu.bsky.social
Xiaoli Sky Wu @xiaoliwu.bsky.social · Apr 2
What contributes to human specific neural specification? Check out these two wonderful preprints from a wonderful scientist Ava carter! 1. www.biorxiv.org/content/10.1...; 2. www.biorxiv.org/content/10.1...

Stay tuned! third preprint is on its way!
Human-chimpanzee tetraploid system defines mechanisms of species-specific neural gene regulation
A major challenge in human evolutionary biology is to pinpoint genetic differences that underlie human-specific traits, such as increased neuron number and differences in cognitive behaviors. We used ...
www.biorxiv.org
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Reposted by GEARs
fnucleosome.bsky.social
FragileNucleosome @fnucleosome.bsky.social · Mar 23
🌱Join us for the first #FragileNucleosome seminar of this spring! We are excited to host @juliamaristany.bsky.social & @chribue.bsky.social this week!
If you have registered before you can join from the same link, if not, don't forget to register!
us06web.zoom.us/webinar/regi...
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Reposted by GEARs
fnucleosome.bsky.social
FragileNucleosome @fnucleosome.bsky.social · Feb 22
🎆Next #FragileNucleosome meeting is less than a week away! We are delighted to host @manucazottes.bsky.social, @robertadolling1.bsky.social & @leandrosboukas.bsky.social ! We will discuss evolution of XIST regulatory network, cancer epigenetics, and MDEMs!
🗓️ us06web.zoom.us/webinar/regi...
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gearseminar.bsky.social
GEARs @gearseminar.bsky.social · Feb 14
After a long break, GEARs is back! We will feature three speakers on Feb 27th, 6PM in Goldenson 122. Please register via docs.google.com/forms/d/e/1F... so we can get enough food and drinks. You can nominate speaker sor volunteer for our future seminars through docs.google.com/forms/d/e/1F....
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