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Genes & Diseases Journal

@genesndiseases.bsky.social

1.4K followers 1.5K following 800 posts

International Open Access journal publishing on molecular and translational medicine. IF 2024,9.4; Scopus Citescore 2024, 8.4.

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Genes & Diseases Journal @genesndiseases.bsky.social · 8d

Genes & Diseases invites reviewers with expertise in:
Human genetics & genomics
Cancer biology
Neurological, cardiovascular, and metabolic disorders
Translational medicine and more
Contact us: [email protected]
#Genetics #PeerReview #GenesAndDiseases

Genes & Diseases Journal @genesndiseases.bsky.social · 3h

CRISPR/CasRx knockdown of Ctnnb1 and Smo inhibits Wnt/β-catenin & Ihh signaling, alleviating osteoarthritis (OA), and holds therapeutic promise for OA. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Genes & Diseases Journal @genesndiseases.bsky.social · 10h

This study shows that #Mesenchymal-#Epithelial transition factor mutations enhance #Cancer immunity and may serve as #Biomarkers across cancer types to guide personalized #Immunotherapy strategies. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

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Genes & Diseases Journal @genesndiseases.bsky.social · 15h

A novel #METTL3 degrader, ZW27941, acts via the VHL-proteasomal pathway, showing promise in enhancing efficacy & overcoming resistance combined with existing treatments for #AcuteMyeloidLeukemia. @uflorida.bsky.social #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Reposted by Genes & Diseases Journal

ESMO - European Society for Medical Oncology @myesmo.bsky.social · 1d

📣 #ESMOImmuno25: Stay ahead in the rapidly evolving field of immuno-oncology. Join the leading experts and pioneers that are driving progress in immuno-oncology.

⏰ Last chance to register and benefit from the best fees! Deadline 8 October 2025. #esmomeetings

🔗 https://ow.ly/ywTB50X7yOo

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Reposted by Genes & Diseases Journal

The ASCO Post @ascopost.bsky.social · 1d

BART Trial Presented at the ASTRO Annual Meeting: Adjuvant RT after cystectomy + chemo in MIBC improves survival with no excess grade ≥3 toxicity

One of the first large randomized trials to show meaningful pelvic relapse reductions, says Vedang Murthy, MD

ascopost.com/news/septemb...

Adjuvant Radiation Therapy Safe and Beneficial in Locally Advanced Muscle-Invasive Bladder Cancer

Adjuvant radiation therapy after radical cystectomy and chemotherapy was found to be safe and efficacious for patients with locally advanced muscle-invasive bladder cancer, according to findings from ...

ascopost.com

Reposted by Genes & Diseases Journal

EACR - European Association for Cancer Research @helloeacr.bsky.social · 19h

Missed our recent free scientific webinar with QIAGEN?

Watch the replay of 'TCR Repertoires of Tumor-Infiltrating γδ T Cells Reveal PD-1-Modulated Reactivity': magazine.eacr.org/qiagen-webin...

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Genes & Diseases Journal @genesndiseases.bsky.social · 1d

This study demonstrates the efficiency and safety of SIN-IL2RG-LV, paving the way for clinical trials in #XSCID treatment. #CellTherapy #MedicalResearch #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Genes & Diseases Journal @genesndiseases.bsky.social · 1d

This research provides a genomic and epigenomic map of ICE syndrome, shedding light on disease mechanisms and guiding the development of future targeted therapies. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Genes & Diseases Journal @genesndiseases.bsky.social · 1d

This review highlights how #TCM compounds and monomers regulate #Ferroptosis, providing mechanistic insights into their therapeutic potential. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

www.sciencedirect.com

Reposted by Genes & Diseases Journal

The ASCO Post @ascopost.bsky.social · 2d

Phase II LUNAR Trial: PSMA-targeted radiopharmaceutical plus SBRT improved PFS in pts with oligometastatic prostate cancer (18 vs 7 mo), which helped to delay ADT by 24 months

Presented by Amar U. Kishan, MD, at the ASTRO Annual Meeting @astro-org.bsky.social

ascopost.com/news/septemb...

Prostate Cancer: Radiopharmaceutical Plus SBRT Delays Progression in Patients With Limited Metastatic Disease

In prostate cancer, radiopharmaceuticals typically target PSMA, delivering precise doses of radiation directly to tumors; these medicines are currently approved for later-stage prostate cancer. The LU...

ascopost.com

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Reposted by Genes & Diseases Journal

IASLC @iaslc.bsky.social · 2d

Registration is open for the 2025 Hot Topic in Basic & Translational Science meeting!
See the outstanding faculty lineup and secure your seat today:
bit.ly/48epcNd

Reposted by Genes & Diseases Journal

EANO @eanoassociation.bsky.social · 2d

👉 We are excited to announce that the #EANO2025 Abstract Book is now available online! Download & explore it today: lnkd.in/dg79p6wM

#AbstractBook #NeuroOncology #neurosurgery #cancernurse #neuropathology #radiotherapy #AHP #btsm

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Genes & Diseases Journal @genesndiseases.bsky.social · 1d

This top-downloaded article from April 2025 maps #ChronicMyeloidLeukemia-specific T cells at single-cell resolution & uncovers interactions between non-#ImmuneCells & T cell subsets in #BoneMarrow, offering novel #Immunotherapy strategies. #medsky OpenAccess: www.sciencedirect.com/science/arti...

www.sciencedirect.com

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Genes & Diseases Journal @genesndiseases.bsky.social · 1d

This review sheds light on the molecular mechanisms regulating endometrial carcinoma, highlights key gaps, and underscores the need for deeper mechanistic insights to inform future therapies. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

www.sciencedirect.com

Reposted by Genes & Diseases Journal

Life Science Network @lifesciencenet.bsky.social · 5d

New AI system could accelerate clinical research.

#science #news #ai #clinicalresearch

www.lifescience.net/news/6581/ne...

New AI system could accelerate clinical research

By enabling rapid annotation of areas of interest in medical images, the tool can help scientists study new treatments or map disease progression.

www.lifescience.net

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Reposted by Genes & Diseases Journal

International Neuroendocrine Cancer Alliance (INCA) @inca-netcancerday.bsky.social · 2d

#NETCancerDay is on November 10th. NETs are easily missed but early diagnosis is possible.
📢Please prepare to join the global NET community to speak in one global voice.
✅Check out INCA’ campaign toolkit how to get involved in NET Cancer Day: incalliance.org/ncd-2025/cam...
#LetsTalkAboutNETs

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Reposted by Genes & Diseases Journal

EACR - European Association for Cancer Research @helloeacr.bsky.social · 2d

You might be interested to know about an upcoming EACR-sponsored meeting organised by the BACR, an affiliated National Society of the EACR.

BACR Annual Meeting 2025
📅 24 October
🌍 Leuven, Belgium

www.bacr.be/annual-meeti...

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Reposted by Genes & Diseases Journal

International Neuroendocrine Cancer Alliance (INCA) @inca-netcancerday.bsky.social · 6d

Free CME Credit: Learn How to Diagnose and Manage Neuroendocrine Cancer in Primary Care.
• Online and self-paced
• Designed by international team of PCPs and NEN experts
• 7 languages
✅Start to #ThinkNENs today: incalliance.org/think-nens/
#LetsTalkAboutNETs

Reposted by Genes & Diseases Journal

Society of Surgical Oncology @socsurgonc.bsky.social · 5d

Applications are open! Serve on an SSO Committee, Subcommittee, or Work Group and help shape the future of surgical oncology. Don’t miss this chance to contribute to advancing our Strategic Plan.

Check your inbox to find the link to apply. Learn more 👉: https://ow.ly/rcI250X5Px9

Reposted by Genes & Diseases Journal

ESMO - European Society for Medical Oncology @myesmo.bsky.social · 3d

🤖 How can multimodal AI support #PrecisionOncology? At #ESMOAI25, the session “Multimodal AI for clinical decision support” will explore tumour boards, real-world data, explainability & integration challenges.

👉 www.esmo.org/meeting-cale...

#ESMOAI25 #DigitalOncology #HealthAI

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Reposted by Genes & Diseases Journal

American Society of Clinical Oncology @ascocancer.bsky.social · 8d

Pembrolizumab is integral to the treatment of both early-stage and metastatic triple-negative #breastcancer. For #ASCODailyNews, Dr. Rita Nanda & Dr. Sarah Poland explore rechallenging with pembro after immune-related adverse events: brnw.ch/21wWdON

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Reposted by Genes & Diseases Journal

European Society for Radiotherapy and Oncology (ESTRO) @estroradiotherapy.bsky.social · 6d

✨The #ESTRO25 Congress Report is out!
📌Green Journal/The Lancet OncolOGY joint session
📌Award-winning papers
📌Track & technique highlights
👉 bit.ly/4nYNI9o
Will your study appear in the report next year?
✅Submit your abstract by 12 Nov! #ESTRO26 bit.ly/4lxLf4o

Reposted by Genes & Diseases Journal

American Association for Cancer Research (AACR) @theaacr.bsky.social · 5d

Blood thinners can be an effective way to manage blood clots during cancer treatment, but they come with their own risks. Could using a lower dose prove effective in the long term? Learn more in Cancer Today: www.cancertodaymag.org/fall-2025/a-...

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BioNews Central @bionewscentral.com · 6d

Researchers found evidence that #AmyotrophicLateralSclerosis (#ALS) may be an #AutoimmuneDisease, showing that patients have elevated numbers of #inflammatory #TCells that mistakenly target a specific protein expressed in #neurons.

Amyotrophic lateral sclerosis (ALS) appears to be an autoimmune disease – BioNews Central

Researchers found evidence that ALS may be an autoimmune disease, showing that patients have elevated numbers of inflammatory T cells that mistakenly target a specific protein expressed in neurons. ...

sbee.link

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Reposted by Genes & Diseases Journal

Precision Oncology News @preconcnews.bsky.social · 6d

The study found that patients with luminal B subtype prostate cancer benefited from the addition of hormone therapy to post-surgery radiation.

Phase II Trial Validates Predictive Biomarker for Hormone Therapy Use in Prostate Cancer

www.precisionmedicineonline.com

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