GigaScience Journal
@gigascience.bsky.social
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The #OpenScience journal from BGI & OUP publishing articles using/generating large datasets. And linked to GigaDB #opendata hosting/analysis repository. Website: http://gigasciencejournal.com
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gigascience.bsky.social
And it’s goodbye from me. Final GigaBlog from outgoing EiC @scedmunds.bsky.social on the major changes at GigaScience Press gigasciencejournal.com/blog/and-its...
gigascience.bsky.social
Happy #PeerReviewWeek: To celebrate we have a proposal in GigaBlog: Why we need a FAIR Principles for Peer Review? gigasciencejournal.com/blog/peerrev... #PRW2025
gigascience.bsky.social
The Return of Asia Nature Challenge #ANC2025
gigasciencejournal.com/blog/the-ret... #AsiaNatureChallenge #ANC2025 #CitizenScience
gigascience.bsky.social
New in our T2T series, and the first published plant (and T2T) genome using CycloneSeq nanopore reads.

Telomere-to-telomere African wild rice (Oryza longistaminata) reference genome reveals segmental and structural variation doi.org/10.1093/giga...
gigascience.bsky.social
A new platform for discovering new bioactive peptides and family-specific analogues, accelerating both natural product discovery and evolutionary research.

PeptideMiner—neuropeptide discovery across the animal kingdom doi.org/10.1093/giga...
PeptideMiner—neuropeptide discovery across the animal kingdom
Abstract. Neuropeptides represent the largest and most diverse class of cell-to-cell signaling molecules, holding important roles in animal physiology and
doi.org
gigascience.bsky.social
A new GNN+DNN model, which combines molecular graphs and fingerprints through a graph attention network architecture.

SynProtX: a large-scale proteomics-based deep learning model for predicting synergistic anticancer drug combinations doi.org/10.1093/giga...
SynProtX: a large-scale proteomics-based deep learning model for predicting synergistic anticancer drug combinations
AbstractMotivation. Drug combination therapy plays a pivotal role in addressing the molecular heterogeneity of cancer, improving treatment efficacy, minimi
doi.org
gigascience.bsky.social
A new #opensource #metabolomics platform dedicated to the selection, integration, and secure (controlled access) sharing of quantitative metabolomics data

MetaboSERV—a platform for selecting, exchanging, and visualizing metabolomics data with controlled data access doi.org/10.1093/giga...
MetaboSERV—a platform for selecting, exchanging, and visualizing metabolomics data with controlled data access
AbstractBackground. The growing number of metabolomics studies, based on high-dimensional data measured by hyphenated mass spectrometry (MS) and/or nuclear
doi.org
gigascience.bsky.social
And read the research in GigaScience here doi.org/10.1093/giga...
gigascience.bsky.social
If you missed our cracking Cassyni webinar yesterday with Arthur Georges and Qiye Li talking about reptile sex-determination and CycloneSeq, the Q&A was a treat as we had many of the worlds top sex chromosome researchers join the discussion. You can watch it here cassyni.com/events/SWHRe...
Cassyni screenshot
gigascience.bsky.social
Tune it to our amazing sex changing reptile genomics webinar starting in about an hour...
gigascience.bsky.social
Sign up for our webinar on Tuesday 26th August on how new long read technologies (including the first CycloneSeq vertebrate genomes) are helping elucidate the sex determination of sex-changing reptiles cassyni.com/events/SWHRe...
gigascience.bsky.social
See also this video where you can see the loss of eyes during development of the olm from 3D imaging data we published youtu.be/OJYafv5lzSk?...
gigascience.bsky.social
Sign up for our webinar on Tuesday 26th August on how new long read technologies (including the first CycloneSeq vertebrate genomes) are helping elucidate the sex determination of sex-changing reptiles cassyni.com/events/SWHRe...
gigascience.bsky.social
New work providing an improved understanding of the epigenomic basis of turbot immune response to mimics of viral and bacterial stimuli

Multiomics uncovers the epigenomic and transcriptomic response to viral and bacterial stimulation in turbot doi.org/10.1093/giga...
Multiomics uncovers the epigenomic and transcriptomic response to viral and bacterial stimulation in turbot
AbstractBackground. Uncovering the epigenomic regulation of immune response is essential for a comprehensive understanding of host defense mechanisms, thou
doi.org
Reposted by GigaScience Journal
aruizherrera.bsky.social
🎉 Another exciting contribution from our lab this summer!

🧬 Nearly complete, gapless genome of the sex-changing central bearded dragon (Pogona vitticeps) shed new light on the mystery of reptile sex determination.

Proud to be part of this collaborative effort!

academic.oup.com/gigascience/...
A near telomere-to-telomere phased genome assembly and annotation for the Australian central bearded dragon Pogona vitticeps
AbstractBackground. The central bearded dragon (Pogona vitticeps) is widely distributed in central eastern Australia and adapts readily to captivity. Among
academic.oup.com
gigascience.bsky.social
Double Dragon Genomes Helping Explain Sex Determination of Reptiles. Two almost complete and gapless genomes of the sex-changing central bearded dragon (Pogona vitticeps) have just been published back-to-back in GigaScience gigasciencejournal.com/blog/double-...