Gladfelter Lab
@gladfelterlab.bsky.social
640 followers
320 following
15 posts
Scientists using microscopes, math, physics and fun to discover how cells work @Duke Cell Biology/BME. https://gladfelterlab.net
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Gladfelter Lab
@gladfelterlab.bsky.social
· Mar 19
Immiscible proteins compete for RNA binding to order condensate layers
Biomolecular condensates mediate diverse and essential cellular functions by compartmentalizing biochemical pathways. Many condensates have internal subdomains with distinct compositional identities. ...
www.biorxiv.org
Gladfelter Lab
@gladfelterlab.bsky.social
· Feb 18
Cooperativity in septin polymerization is tunable by ionic strength and membrane adsorption
Cells employ cytoskeletal polymers to move, divide, and pass information inside and outside of the cell. Previous work on eukaryotic cytoskeletal elements such as actin, microtubules, and intermediate...
www.biorxiv.org
Gladfelter Lab
@gladfelterlab.bsky.social
· Feb 18
Lipid packing and local geometry influence septin curvature sensing
Septins assemble into scaffolds that direct cell growth and morphology that are often localized to the plasma membrane. While septins preferentially bind convex membranes via amphipathic helices, thei...
www.biorxiv.org
Gladfelter Lab
@gladfelterlab.bsky.social
· Jan 19
Integrating cell and planetary scales to address climate resilience
The climate crisis is a multiscale problem that requires transdisciplinary expertise for understanding and engineering climate resilience. Cells are the first responders of the biosphere and yet cell…
meetings.embo.org
Gladfelter Lab
@gladfelterlab.bsky.social
· Jan 19
Physiology: Modern Cell Biology Using Microscopic, Biochemical and Computational Approaches | Marine Biological Laboratory
This course is at the forefront of new tools — molecular, computational, biophysical — as it prepares students to tackle emerging biological questions.
www.mbl.edu