Previous research suggests that dietary fiber (DF) intake may help reduce chronic low-grade inflammation (CLGI), a condition linked to the early development of cardiometabolic risk factors. Childhood ...

The 13th Gut Microbiota for Health World Summit took place 15-16 March 2025 in Washington, D.C., and it focused on advances in microbiome research to diagnose, prevent, and manage gastrointestinal and extra-intestinal conditions. Find out more about the most valuable takeaways from the event.

Many patients with IBS find that wheat or gluten triggers gastrointestinal symptoms, prompting them to exclude these foods from their diets. A new study highlights how patients’ expectations and beliefs shape symptom modulation and dietary choices in IBS.

The gut microbiota, composed of trillions of microorganisms, plays a key role in bidirectional communication between the gut and brain, particularly during early life. The first two postnatal years represent a critical window when the exposome—the totality of all environmental exposures—shapes neurodevelopment via the microbiota–gut–brain axis. Exposome factors such as diet, birth mode, antibiotic use, infections, and xenobiotics can alter microbial composition and function, with downstream e...

Digestive Disease Week 2025 featured recent basic, translational, and clinical research into the microbiome. Find out more about the main takeaways relevant for your clinical practice selected by GMFH editors.

Atherosclerosis reflects a chronic inflammatory process of arteries. The origin of chronic vascular inflammation has been associated over a long time primarily with lipid disorders, but evidence from the past years has suggested that lipid-independent pathways are also involved. Recent research has demonstrated that the gastrointestinal microbiota has an impact on the development of atherosclerosis. Many clinical studies have revealed that there exist altered gut microbiota and increased inte...

The gut microbiome influences how we respond to food and not all nutrients benefit us equally, something we’ve known for a while. A new review article delves into how our gut microbiome shapes the impact of diet on human health, leading to rethinking current nutrition guidelines.

This article highlights new evidence on prebiotics improving cognition in older adults and explores implications for the microbiota-gut-brain axis.

Understanding how the gut microbiome changes precede and drive disease offers potential for developing personalized therapeutics

Unique biological, exposomal, economic and sociocultural factors shape resilience and brain health across the globe; this Review discusses underlying mechanisms of resilience, measurement approaches, operationalization and research gaps.

Recent studies are beginning to reveal the potential role of different dietary patterns in shaping the gut microbiome composition and their association with aging and health outcomes.

A study reveals a gut–brain sensory pathway through which the microbial component flagellin activates neuropod cells in the colon to signal the brain and reduce feeding in mice.

A new study reveals that despite geographical and cultural differences, infants undergo similar microbial changes in their intestines.

Does a prospective father’s gut microbiota matter?

A new analysis supports dietary guidelines to reduce the consumption of processed meat, sugar-sweetened beverages and trans-fatty acids — highlighting the need for a collaborative, meticulous health assessment framework for ultra-processed foods.

npj Biofilms and Microbiomes - Host-microbiome relationship in depression: can human induced pluripotent stem cells play a role in unravelling mechanisms?

Fecal microbiota transplants (FMTs) may not always effectively restore small bowel microbiota due to regional differences in gut environments, potentially causing unintended effects on metabolism and ...

This article presents recent and compelling examples of microbiome-based treatments that are ripe for clinical adoption and discusses challenges and opportunities facing the field based on expert inte...

This Perspective explores how the gut microbiota influences the function and heterogeneity of microglia, highlighting their roles in neurological and neuropsychiatric disorders, and discusses the therapeutic potential, challenges and clinical implications of targeting microbiota–microglia interactions.

This article features key discoveries in gut microbiome research from 2024 selected by the Gut Microbiota for Health editorial team. Research highlights include basic, translational, and clinical microbiome research with significant implications for current and future research in the field.

Brown et al. show that bacterial sphingolipids delivered by outer membrane vesicles (OMVs) persist within mammalian immune cells and promote IL-10 secretion via the mevalonate pathway. This sphingolip...