h-sokol.bsky.social
@h-sokol.bsky.social
New link between the gut Microbiome, bile acids and Osteoarthritis :

Osteoarthritis treatment via the GLP-1–mediated gut-joint axis targets intestinal FXR signaling | Science

www.science.org/doi/10.1126/...
Osteoarthritis treatment via the GLP-1–mediated gut-joint axis targets intestinal FXR signaling
Whether a gut-joint axis exists to regulate osteoarthritis is unknown. In two independent cohorts, we identified altered microbial bile acid metabolism with reduced glycoursodeoxycholic acid (GUDCA) i...
www.science.org
April 9, 2025 at 8:09 AM
Reposted
Ravie d'avoir présenté nos travaux aux #JFHOD2025.
Un grand merci à Zhan qui a mené ce projet de collaboration avec Biocodex ainsi qu'à Loic, Laura, Rand, @jeremielefevre.bsky.social et @h-sokol.bsky.social
Félicitations @nathalierolhion.bsky.social pour le prix de la meilleure communication orale pour les travaux de son groupe sur les effets de S. boulardii sur le microbiote en collaboration avec Biocodex

@microbiotainst.bsky.social
@sorbonne-universite.fr @inserm.fr @glimmerfhu.bsky.social
March 23, 2025 at 9:16 AM
Intestinal Epithelial Serotonin as a Novel Target for Treating Disorders of Gut-Brain Interaction and Mood - Gastroenterology www.gastrojournal.org/article/S001...
Intestinal Epithelial Serotonin as a Novel Target for Treating Disorders of Gut-Brain Interaction and Mood
Increased serotonin in the gut epithelium is anxiolytic and antidepressive which is mediated through vagal signaling. Maternal selective serotonin reuptake inhibitor exposure is associated with a risk...
www.gastrojournal.org
April 4, 2025 at 4:50 PM
Metagenome-informed metaproteomics of the human gut microbiome, host, and dietary exposome uncovers signatures of health and inflammatory bowel disease: Cell www.cell.com/cell/fulltex...
Metagenome-informed metaproteomics of the human gut microbiome, host, and dietary exposome uncovers signatures of health and inflammatory bowel disease
A metagenome-informed metaproteomics approach unravels the interplay between the host, gut microbiome, and diet in animal models as well as in human cohorts and identifies disease biomarkers of dysbio...
www.cell.com
January 22, 2025 at 7:33 PM