Beth Hogg
@hairofthehogg.bsky.social
Postdoc in @mchanggroup at Princeton University. PhD Turner lab at The University of Manchester.
New paper from the MChang lab!
Congratulations to former student Eli and the team on their new paper in Nature Chemical Biology! Here they show that the difference in radical rebound of FeII/aKG halogenases is uniquely controlled by the switching of the metal ligand bond axes! Take a look: www.nature.com/articles/s41...
Dynamic metal coordination controls chemoselectivity in a radical halogenase - Nature Chemical Biology
Radical FeII/α-ketoglutarate-dependent halogenases are powerful biocatalysts for C–H functionalization. Here, the authors reveal the mechanistic basis for chemoselectivity in a lysine halogenase.
www.nature.com
November 21, 2025 at 3:21 PM
New paper from the MChang lab!