Hamidreza Ghafouri
@hamidrgh.bsky.social
PhD student @Biocomputing UP lab @University of Padova-Italy 🇮🇹
Research IDPs , Conformational ensembles🍝
Hamidrgh.github.io/hamidrgh
Research IDPs , Conformational ensembles🍝
Hamidrgh.github.io/hamidrgh
We also outline key challenges in the field—such as force field accuracy, efficient sampling, and environmental dependency—and call for collaborative benchmarking and standardized protocols.
Kudos to all co-authors and contributors who made this work possible!
Kudos to all co-authors and contributors who made this work possible!
April 7, 2025 at 9:08 AM
We also outline key challenges in the field—such as force field accuracy, efficient sampling, and environmental dependency—and call for collaborative benchmarking and standardized protocols.
Kudos to all co-authors and contributors who made this work possible!
Kudos to all co-authors and contributors who made this work possible!
Our framework is built around three pillars:
🔹Experimental techniques
🔹 Computational ensemble generation
🔹 Ensemble validation
🔹Experimental techniques
🔹 Computational ensemble generation
🔹 Ensemble validation
April 7, 2025 at 9:08 AM
Our framework is built around three pillars:
🔹Experimental techniques
🔹 Computational ensemble generation
🔹 Ensemble validation
🔹Experimental techniques
🔹 Computational ensemble generation
🔹 Ensemble validation
🍝 Disordered proteins are central to many biological processes, but their dynamic nature makes structural characterization a major challenge. Here, we present a modular framework that bridges experimental methods with computational tools, like molecular dynamics, knowledge-based sampling, and ML.
April 7, 2025 at 9:08 AM
🍝 Disordered proteins are central to many biological processes, but their dynamic nature makes structural characterization a major challenge. Here, we present a modular framework that bridges experimental methods with computational tools, like molecular dynamics, knowledge-based sampling, and ML.