Health and Environmental Sciences Institute (HESI)
@hesiglobal.bsky.social
19 followers 11 following 12 posts
HESI is a non-profit institution whose mission is to collaboratively identify and help to resolve global health and environmental challenges through the engagement of scientists from academia, government, industry, NGOs, and other strategic partners.
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hesiglobal.bsky.social
The Sept issue of HESI Global Insights is here! 🌍 From #FDA and #NIEHS collaborations to global work in toxicology, biomarkers & more—HESI Global continues to drive science for a safer world.
Read now: hesiglobal.org/hesi-insight...
#HESI #PublicHealth #EnvironmentalScience #Toxicology
HESI Global Newsletter - Insights - September 2025
hesiglobal.org
hesiglobal.bsky.social
New article from the HESI eSTAR Committee shows how transcriptomic points of departure (tPODs) are changing the game for risk assessment and reducing the need for long-term animal testing.
Read more: doi.org/10.1093/toxs...
#HESI #eSTAR #Toxicology #NGRA #Omics #AltMethods
hesiglobal.bsky.social
New publication from the HESI Global Cardiac Safety Committee! Human-relevant cardiac models like hiPSC-CMs and engineered tissues offer earlier, more ethical detection of cardiotoxicity in drug development. Read: hesiglobal.org/publication/...
#HESIGlobal #NAMs #CardiacSafety #3Rs #Toxicology
New HESI Cardiac Safety Publication: Validating and Using Cardiac NAMs for Toxicity Screening and Drug Development. International Journal of Toxicology. Pierson et al., 2025.
hesiglobal.org
Reposted by Health and Environmental Sciences Institute (HESI)
broadinstitute.org
The Omics for Assessing Signatures for Integrated Safety (OASIS) consortium, launched by Broad, @hesiglobal.bsky.social & scientific partners, with @malifesciences.bsky.social support, is sharing data using cell-based omics tools to reduce reliance on animals in drug & agrochemical safety testing.
Collaboration aims to reduce animal use in drug safety testing
OASIS consortium is evaluating omics tools in cells, including Cell Painting and transcriptomics, to predict liver toxicity of potential new medicines and agrochemicals.
www.broadinstitute.org
hesiglobal.bsky.social
The July 2025 issue of #HESIGlobal Insights is out now!
AI in health, NAMs in immuno-safety, nitrosamines, new publications & more.
Catch up on global science for a safer world.
🔗 hesiglobal.org/hesi-insight...
HESI's July 2025 Newsletter - Insights
hesiglobal.org
hesiglobal.bsky.social
🔍 From virtual control groups to smart biodiversity inventorying—AI is transforming science. Explore real-world case studies, interactive panels, and a collaborative roadmap-building experience at #HESI’s AI and health protection conference, June 4–5.
Register now: hesiglobal.org/hesiannualme...
Reposted by Health and Environmental Sciences Institute (HESI)
nc3rs.bsky.social
SURVEY: New approach methodologies in safety assessment

Are you involved in the development and application of replacement technologies for toxicity testing or submission and assessment of data for regulatory decision making? Help shape our plans for the coming years: nc3rs.org.uk/our-portfoli...
Icons representing new approach methodologies and chemical and drug safety testing, in a speech bubble.
Reposted by Health and Environmental Sciences Institute (HESI)
drannecarpenter.bsky.social
Have you invented a liver cell/tissue model? Want to validate it for tox?

You can apply to test your model’s ability to detect liver toxicity mechanisms-OASIS Consortium will suggest subsets of compounds based on your system's scale; you run yr assay.

Email [email protected] for more!
pls RT!
OASIS logo: Omics for Assessing Signatures for Integrated Safety Consortium
hesiglobal.bsky.social
🚨 HESI's Environmental Epidemiology Committee is proud to support the new Special Interest Group on Quantitative Bias Analysis (QBA) within ISEE @isee-global.bsky.social. Led by #HESI Co-Chair David Miller, this SIG will promote practical QBA use in environmental health.
🔗 ow.ly/qfG550VooZV
hesiglobal.bsky.social
🚨 The March HESI Insights is out! From TGx-DDI’s FDA submission to nitrosamine research and cell therapy safety—discover how HESI is shaping science for global health.
🔗 hesiglobal.org/hesi-insight...
#HESI #HumanHealth #EnvironmentalHealth
HESI's March 2025 Newsletter - Insights
hesiglobal.org
hesiglobal.bsky.social
Early-career scientists in cardiac safety—this one’s for you!
Apply for the HESI Early Career Seminar Award:
$500
Present your research in a public webinar
Connect w/experts in tox & pharmacology

Deadline: April 25, 2025
Details hesiglobal.org/cardiac-safe...

#CardiacSafety #EarlyCareerScience
HESI Cardiac Safety Committee
hesiglobal.org
hesiglobal.bsky.social
Looking to Network with Scientists in the DC Area?
Register now for an opportunity to network with employers, job seekers, and colleagues seeking to expand their professional connections! #Networking #Science #DCScientists #Toxicology #RegulatoryScience
hesiglobal.org/event/hesi-n...
HESI Networking Event: March 5, 2025
hesiglobal.org
Reposted by Health and Environmental Sciences Institute (HESI)
drannecarpenter.bsky.social
We've a postdoc opening for our lab at the Broad: Cambridge MA!

Must have experience in toxicology + data science

Work on the wonderful OASIS dataset we are producing... Cell Painting, transcriptomics, proteomics in various liver cell and tissue models!

broad.io/mlcbpostdoc
Image of the job posting (see URL for full text instead)
hesiglobal.bsky.social
Save the Date! We are excited to announce the HESI Biannual Meeting, taking place on June 4–5, 2025, in Washington, DC! Join us in shaping the future of science and health through collaboration, innovation, and AI-driven solutions!
Learn More and Stay Updated: hesiglobal.org/hesiannualme...