David Hofer
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hofer.bsky.social
David Hofer
@hofer.bsky.social
I work on software for tracking genome sequences, edits and variants. Cat dad. Boston, MA
Saw some lovely offshore wind farms flying out of Amsterdam today
February 2, 2026 at 9:34 PM
I’m digitizing some records I came into possession of. Toledo is fascinated with the turntable
January 7, 2026 at 12:54 AM
I guess this platform is getting a bunch of new ex-twitter Japanese users? Here’s my entry for the cat club #Blueskyねこ部
December 25, 2025 at 5:14 PM
December 25, 2025 at 5:00 PM
For the non-bioinformaticians who are following me, here are a couple pictures of my cats as compensation for having to see my GenHub posts
December 9, 2025 at 8:44 PM
The paws are interleaved. He’s trying to tell me he’s with Tenet
November 22, 2025 at 11:02 PM
Toledo continues his love/hate relationship with the paper that makes scary crackling noises but feels so comfortable
October 8, 2025 at 2:59 PM
He looks a lot like my Hamburg!
October 7, 2025 at 10:09 PM
Yin and yang
August 12, 2025 at 1:42 PM
It seems to be the summer of woodchucks. I’ve never seen so many around.
August 6, 2025 at 9:50 PM
Saw this over on the other site, man TDF fans are the best
July 24, 2025 at 8:16 PM
Whenever I’m standing around with nothing better to do, like watching fireworks, I imagine talking to someone who lived here 200 or 300 years ago. That big skyscraper to the right? It’s part way between the South End and the Charles. Yeah, they filled in all the swamp there
July 5, 2025 at 2:40 AM
This doesn’t happen often, but today I was preoccupied thinking about how I didn’t make it through grad school. Toledo was there to help 🙏🏻
June 28, 2025 at 11:32 PM
One of my cats, when confronted with near-record heat, is like Ford Prefect when confronted with Vogon poetry. He hates it but is resigned to it.

The other is like Arthur Dent. He lolls around, then decides he actually kind of likes it
June 24, 2025 at 10:39 PM
Yeet me into the future where the New England grid isn’t running on 12% oil and 48% natural gas on a hot day. www.iso-ne.com
June 24, 2025 at 10:31 PM
Cat reactions to a heat wave
June 23, 2025 at 1:43 PM
Toledo the tuxedo cat and Hamburg (the tabby who claims my chair) say hi
June 15, 2025 at 9:12 PM
32 minutes before their dinner time
May 11, 2025 at 8:01 PM
I want to get dinner but I can’t get dinner
February 11, 2025 at 11:30 PM
Good pillows make good neighbors
February 1, 2025 at 4:59 PM
The cold weather finally prompted me to set up a bird feeder to help them get through to spring. I put it by my back window so I could watch them. My cats are also entertained
January 22, 2025 at 2:05 AM
Rare Hamburg blep
January 5, 2025 at 6:16 PM
I can’t believe it, their paws are touching 😻
December 16, 2024 at 4:30 PM
As someone working in synthetic biology, I appreciate that although Frieren the mage knows lots of spells for offensive and defensive magic, and who knows what else, her favorite spell is one that creates a field of flowers
November 20, 2024 at 12:05 AM
Toledo toes
November 7, 2024 at 3:33 AM