HorikitaSaku
@horikitasaku.bsky.social
A student aspiring to leverage AI for advancing natural and fundamental sciences.
CN/EN/JP; Kaggle Master
CN/EN/JP; Kaggle Master
Reposted by HorikitaSaku
311 new entries in #PDBrelease (PDBe.org/latest) -- including new insight into ATPases (our cell’s powerhouses) -- specifically ATP hydrolysis in a human AAA+ protein ➡️ pdbe.org/8ooi, with a 2.6 Angstrom Cryo-EM map ➡️ emdb-empiar.org/EMD-17016. Published @NatureChemistry
January 31, 2024 at 5:16 PM
311 new entries in #PDBrelease (PDBe.org/latest) -- including new insight into ATPases (our cell’s powerhouses) -- specifically ATP hydrolysis in a human AAA+ protein ➡️ pdbe.org/8ooi, with a 2.6 Angstrom Cryo-EM map ➡️ emdb-empiar.org/EMD-17016. Published @NatureChemistry
Reposted by HorikitaSaku
On #WorldCancerDay, we’re highlighting antibody-maytansinoid conjugates (AMCs)! Our featured article explores these tumour targeting agents that inspired #PDBart.
🔗 article:
www.ebi.ac.uk/pdbe/news/ta...
🔗 protein structure:
pdbe.org/7e4q
#WCD2024
🔗 article:
www.ebi.ac.uk/pdbe/news/ta...
🔗 protein structure:
pdbe.org/7e4q
#WCD2024
February 4, 2024 at 5:15 PM
On #WorldCancerDay, we’re highlighting antibody-maytansinoid conjugates (AMCs)! Our featured article explores these tumour targeting agents that inspired #PDBart.
🔗 article:
www.ebi.ac.uk/pdbe/news/ta...
🔗 protein structure:
pdbe.org/7e4q
#WCD2024
🔗 article:
www.ebi.ac.uk/pdbe/news/ta...
🔗 protein structure:
pdbe.org/7e4q
#WCD2024
Reposted by HorikitaSaku
This week's #PDB release has 105 new entries, including this X-Ray structure of the adenylyl cyclase of Ziziphus jujuba (Chinese date fruit) (pdbe.org/8H92). Find all the new entries at pdbe.org/latest
January 3, 2024 at 11:08 AM
This week's #PDB release has 105 new entries, including this X-Ray structure of the adenylyl cyclase of Ziziphus jujuba (Chinese date fruit) (pdbe.org/8H92). Find all the new entries at pdbe.org/latest
Reposted by HorikitaSaku
Protein-Vec enhances protein function prediction by combining independently contrastively learned protein classifiers for EC, GO, PFAM, Gene3D, and TMscore (Aspect-vecs) into a merged embedding to boost prediction performance.
📄 biorxiv.org/content/10.1...
💾 github.com/tymor22/prot...
📄 biorxiv.org/content/10.1...
💾 github.com/tymor22/prot...
November 28, 2023 at 4:40 AM
Protein-Vec enhances protein function prediction by combining independently contrastively learned protein classifiers for EC, GO, PFAM, Gene3D, and TMscore (Aspect-vecs) into a merged embedding to boost prediction performance.
📄 biorxiv.org/content/10.1...
💾 github.com/tymor22/prot...
📄 biorxiv.org/content/10.1...
💾 github.com/tymor22/prot...
Reposted by HorikitaSaku
Today is a historical day that marks the approval of CRISPR gene therapy for sickle cell anaemia and beta-thalassemia.
10 years separate proof-of-concept paper from @doudna_lab to a real therapy by @VertexPharma and @CRISPRTX!
Exciting times!
https://www.nature.com/articles/d41586-023-03590-6
10 years separate proof-of-concept paper from @doudna_lab to a real therapy by @VertexPharma and @CRISPRTX!
Exciting times!
https://www.nature.com/articles/d41586-023-03590-6
UK first to approve CRISPR treatments for diseases: what you need to know
Nature - The landmark decision could transform the treatment of sickle-cell disease and beta-thalassaemia — but the technology is expensive.
www.nature.com
November 17, 2023 at 10:34 AM
Today is a historical day that marks the approval of CRISPR gene therapy for sickle cell anaemia and beta-thalassemia.
10 years separate proof-of-concept paper from @doudna_lab to a real therapy by @VertexPharma and @CRISPRTX!
Exciting times!
https://www.nature.com/articles/d41586-023-03590-6
10 years separate proof-of-concept paper from @doudna_lab to a real therapy by @VertexPharma and @CRISPRTX!
Exciting times!
https://www.nature.com/articles/d41586-023-03590-6
November 17, 2023 at 10:29 AM
Reposted by HorikitaSaku
Today I received a positive decision for my article after 14(!) months of waiting.
The comments from 2 rounds of reviews were 4 sentences in total...
Come on academia, you can do better.
#phdchat
The comments from 2 rounds of reviews were 4 sentences in total...
Come on academia, you can do better.
#phdchat
November 10, 2023 at 4:18 PM
Today I received a positive decision for my article after 14(!) months of waiting.
The comments from 2 rounds of reviews were 4 sentences in total...
Come on academia, you can do better.
#phdchat
The comments from 2 rounds of reviews were 4 sentences in total...
Come on academia, you can do better.
#phdchat