Attended some interesting and insightful talks on the first day of the #festivalofgenomics. Feeling inspired and ready to do it again tomorrow!

#FoG2026
@fogenomics.bsky.social

A appraisal of PRS informed prostate cancer screening by @amitsud.bsky.social, showing that the PRS approach resulted in more biopsies, fewer detections of clinically significant cancers, and increased overdiagnosis of low-grade tumours

www.sciencedirect.com/science/arti...

Applications for the 2026 Summer Student Scholarship Scheme are now open! This is for undergraduates going into their final year, to work with us at the ICR over the summer.

Please share with anyone who may be interested www.icr.ac.uk/study-and-ca...

Happy New Year! ICYMI have a look at our mince pie taste test from last year. Looking forward to the exciting research to come (and more taste tests!)

We are pleased to announce the results of the annual Houlston Lab mince pie taste test! This year, we restricted to the standard supermarket mince pies!

#christmas #mincepie #tastetest

We are pleased to present our manuscript on the annotation of clear cell Renal Cell Carcinoma #GWAS risk loci, recently published in @commsbio.nature.com

www.nature.com/articles/s42...

#ccRCC #cancer #genetics #genomics #KidneyCancer

Heads up: ignore samtools dot org, similarly minimap2 dot com and likely others. It's owned by a known phishing site and while the binaries they offer look valid currently (but note they may be serving us different binaries to others), that could change.

Ie: it's not us (Samtools team)! Be warned

✅ Published in @natureportfolio.nature.com today, the paper describing the initial whole-genome sequencing analysis of 500,000 UK Biobank participants.

Read here: www.nature.com/articles/s41...

An incredibly valuable tool that we use all the time! Thank you to everyone at @ucscgenomics.bsky.social that maintains it for us!

Excited to launch our AlphaGenome API goo.gle/3ZPUeFX along with the preprint goo.gle/45AkUyc describing and evaluating our latest DNA sequence model powering the API. Looking forward to seeing how scientists use it! @googledeepmind

Textbooks: “Enhancers are just a bunch of TFBSs”

But how do they REALLY work?

New paper with many contributors here @berkeleylab.lbl.gov, @anshulkundaje.bsky.social, @anusri.bsky.social

A 🧵 (1/n)

Free access link: rdcu.be/erD22

It's not all work and no play in the Houlston Lab. We had our annual #Easter taste test! Returning to hot cross buns this year. We went a bit maverick and allowed some more ... unconventional varieties!

#hotcrossbuns #tastetests

📸: @jessicamayh.bsky.social

We are excited to announce our latest publication in #BloodCancerJournal of our Two-Sample MR analysis to investigate causal relationships between 446 immune cell traits and 6 B-cell malignancies

📄 www.nature.com/articles/s41...

#cancer #genetics #Bcell #bloodcancer #drugdiscovery #MR

In response to a recent Guardian article about why approved researchers in China can access our data, we have provided some additional information for our participants, including how we follow Government guidance on who can use UK Biobank.

Please read here: ow.ly/yWsi50VAIIH

Today is #InternationalWomensDay 👏

We are incredibly proud to celebrate the women of the ICR who are dedicated, driven, and determined to make a difference.

You inspire us every day 👩‍🔬👩‍💻👩‍💼

#IWD2025 #AccelerateAction

The team is at the #FestivalOfGenomics! If you see us, come say hi!

#FOG25 #genomics