Institute of Biotechnology
@ibtcas.bsky.social
29 followers 40 following 17 posts
Insight into structural, protein and cellular biology leads to new therapies. www.ibt.cas.cz
Posts Media Videos Starter Packs
ibtcas.bsky.social
RNA is still waiting for its “AlphaFold moment.” 🔬✨
At IBT CAS we’re tackling this challenge head-on.
Read more 👉 1url.cz/YJhsw
ibtcas.bsky.social
Don’t miss the opportunity!
structbiocssb.bsky.social
Protein Production Hands-On Workshop Dates: December 2 – 4, 2025 Venue: BIOCEV, Vestec Registration Deadline: October 31, 2025 Cost: Free of charge (accommodation not included) Registration Link: forms.biocev.org/index.php/14... Workshop Page: www.ibt.cas.cz/en/core-faci...
ibtcas.bsky.social
🆕𝐍𝐞𝐰 𝐫𝐞𝐯𝐢𝐞𝐰 𝐟𝐫𝐨𝐦 𝐨𝐮𝐫 𝐋𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲 𝐨𝐟 𝐋𝐢𝐠𝐚𝐧𝐝 𝐄𝐧𝐠𝐢𝐧𝐞𝐞𝐫𝐢𝐧𝐠!
Colleagues explored key drivers of metastatic non-small cell lung cancer (mNSCLC):
🔹 tumor heterogeneity
🔹 oncogenic drivers & resistance
🔹 immunosuppressive TME
📖 biosignaling.biomedcentral.com/articles/10....
ibtcas.bsky.social
🚨 New paper out!
We built fiSPR, a platform combining SPR biosensing + light 💡 to study light-responsive proteins.

🔹 Blue light → EL222 dimerization + DNA binding
🔹 UV light → interleukin–receptor interactions

📖 doi.org/10.1016/j.bi...
ibtcas.bsky.social
🎉Congratulations to our colleague Daniel Žucha on receiving the 𝙔𝙤𝙪𝙣𝙜 𝙉𝙚𝙪𝙧𝙤𝙨𝙘𝙞𝙚𝙣𝙩𝙞𝙨𝙩𝙨 𝘼𝙬𝙖𝙧𝙙 𝙛𝙤𝙧 𝙊𝙪𝙩𝙨𝙩𝙖𝙣𝙙𝙞𝙣𝙜 𝙒𝙤𝙧𝙠 (𝟮𝟬𝟮𝟯–𝟮𝟬𝟮𝟰) 🧠✨
The prize was awarded by the Czech Neuroscience Society at the biannual #CNS2025 meeting for his work published in PNAS
👉pnas.org/doi/10.1073/pn…
👏
ibtcas.bsky.social
At @eisg2025 in Malmö 🇸🇪:
🎤Valeria Fabríciová gave a talk on sex differences in ISL1-deficient diabetic mouse model
📸Věra Slaninová presented her poster on ISL1 and epigenetic regulation in pancreatic endocrine development
Great discussions, and inspiration for future research. Proud of our team! 💡
ibtcas.bsky.social
𝙋𝙤𝙡𝙞𝙨𝙝 🇵🇱 𝙖𝙣𝙙 𝘾𝙯𝙚𝙘𝙝 🇨🇿 𝙍𝙚𝙨𝙚𝙖𝙧𝙘𝙝 𝙏𝙚𝙖𝙢𝙨 𝙈𝙚𝙚𝙩 𝙞𝙣 𝙋𝙤𝙯𝙣𝙖𝙣
📅From Aug 25–29, IBT CAS (Prof. Bohdan Schneider) met with IBCH PAS (Prof. Marta Szachniuk) in Poznań.
🔬 Joint project: AI & graph-based tools for RNA 3D models
🌍 Goal: open-access solutions for computational structural biology.
ibtcas.bsky.social
🧠Don’t miss two outstanding neuroscience lectures!
📅Sept 5, 2025
13:00 Prof. Marcela Pekna – “𝙄𝙢𝙥𝙧𝙤𝙫𝙞𝙣𝙜 𝙨𝙩𝙧𝙤𝙠𝙚 𝙧𝙚𝙘𝙤𝙫𝙚𝙧𝙮 – 𝙛𝙧𝙤𝙢 𝙩𝙧𝙖𝙣𝙨𝙘𝙧𝙞𝙥𝙩𝙤𝙢𝙞𝙘𝙨 𝙩𝙤 𝙣𝙚𝙬 𝙩𝙧𝙚𝙖𝙩𝙢𝙚𝙣𝙩 𝙨𝙩𝙧𝙖𝙩𝙚𝙜𝙞𝙚𝙨”
14:00 Prof. Milos Pekny – “𝘼𝙨𝙩𝙧𝙤𝙘𝙮𝙩𝙚𝙨 𝙖𝙨 𝙢𝙖𝙟𝙤𝙧 𝙥𝙡𝙖𝙮𝙚𝙧𝙨 𝙞𝙣 𝘾𝙉𝙎 𝙙𝙞𝙨𝙚𝙖𝙨𝙚𝙨”
📍 IBT, BIOCEV campus, Vestec
ibtcas.bsky.social
🚀Věda, která mění životy!
Naše kolegyně Kateřina Komrsková patří mezi světovou špičku v oblasti reprodukční biologie. 🔬✨
V rozhovoru mluví nejen o mužské neplodnosti, ale i o objevech, které mohou pomoci zachránit ohrožené druhy. 🌍💚
👉https://1url.cz/dJVGl
ibtcas.bsky.social
🔬 Teach Me in 10: Future of Molecular Diagnostics is coming up!
Join this free event on NGS 🧬, liquid biopsy 💧 & AI diagnostics 🤖.
🎤 Proud that Mikael Kubista from our Institute will be speaking!
👉 1url.cz/yJaXV
ibtcas.bsky.social
🚀New publication alert!
In #OpenScience, raw data matters. Meet the Molecular Biophysics Database (MBDB) – a new platform to share and reuse raw data from key biophysical methods, built on FAIR principles.
📄https://link.springer.com/article/10.1007/s00249-025-01789-1
ibtcas.bsky.social
Two new top scientists join the International Advisory Board of IBT CAS: Prof. Emanuela Tolosano (Turin) & Prof. Carsten Janke (Orsay/Paris). 🌍
Their expertise in heme metabolism and cytoskeleton biology will support IBT’s strategic growth. 🔬
More: www.ibt.cas.cz/en/news/Inte...
ibtcas.bsky.social
🎉 Big congrats to our amazing PhD student Adéla Karhanová (Laboratory of Structural Proteins, Z. Lánský) on receiving the DIGS-ILS Fellow Award 2025! 🧪✨
We’re proud to see her talent and hard work recognized in such great company!
Keep shining, Adéla! 🌟
👉 www.digs-ils.phd/news/2025/06...
DIGS-ILS Fellow Awards 2025
Awards given to five DIGS-ILS PhD students
www.digs-ils.phd
ibtcas.bsky.social
New biotech startup Carta Genum, founded by our colleagues Lukas Valihrach & Daniel Žucha, was introduced at #Science4Business.

Born at IBT, supported by SIC, and now ready for the market. Good luck on the journey ahead! 👏
#biotech #spatialbiology #startups
ibtcas.bsky.social
🧬 New study: High-affinity Myomedin binders (MLE variants) for PD-L1 detection in NSCLC.
Validated in FFPE tissues, some outperform 28-8 & 22C3 diagnostic antibodies.
Work by @ibtcas + partners
🔗 translational-medicine.biomedcentral.com/articles/10....
ibtcas.bsky.social
🏅𝗧𝗵𝗲 𝗜𝗻𝘀𝘁𝗶𝘁𝘂𝘁𝗲 𝗼𝗳 𝗕𝗶𝗼𝘁𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆 𝗵𝗮𝘀 𝗿𝗲𝗰𝗲𝗶𝘃𝗲𝗱 𝘁𝗵𝗲 𝗽𝗿𝗲𝘀𝘁𝗶𝗴𝗶𝗼𝘂𝘀 𝗛𝗥 𝗘𝘅𝗰𝗲𝗹𝗹𝗲𝗻𝗰𝗲 𝗶𝗻 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗔𝘄𝗮𝗿𝗱🔹
This recognition is not just a formal milestone for us—it is a commitment to building an open, motivating, and transparent research organization.
@akademievedcr.bsky.social
ibtcas.bsky.social
ʟᴇᴄᴛᴜʀᴇꜱ, ꜱᴜɴ ᴀɴᴅ ꜱᴄɪᴇɴᴄᴇ ɪɴ ʟᴜʜᴀčᴏᴠɪᴄᴇ 🎤🧬
Alice a Pavel took the stage at the 1st CS Congress of Medical Genetics in Luhačovice - thanks to everyone who joined!
#GeneCore #genetics #Luhačovice #science
Reposted by Institute of Biotechnology
akademievedcr.bsky.social
🔁 Horizontální mitochondriální transfer je společným jmenovatelem více než 20 typů nádorových onemocnění.

Více⬇️
1url.cz/Q1yqT