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Chris Seymour @iiseymour.bsky.social · May 30

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Chris Seymour @iiseymour.bsky.social · May 22

Request* register.nanoporetech.com/hyper-baseca...

Emerging Hyper Basecalling | Oxford Nanopore

This form allows you to confirm your interest in emerging hyper basecalling.

register.nanoporetech.com

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Chris Seymour @iiseymour.bsky.social · May 21

Dorado is 1.0! 🎉

LC25 release adds v5.2 DNA/RNA models with a new suite of mod models that are higher accuracy, lower FP rates, and significantly faster.

- Introducing dorado variant 👀
- HAC error rate is down over 25%.
- New 2’Ome mod models
- Hopper & Blackwell SUP speed ups

#Nanoporeconf

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Chris Seymour @iiseymour.bsky.social · Apr 2

Yes, you don’t want to be using system memory as GPU mem overflow medium.com/@usamakenway...

Increase CUDA memory with Sysmem Fallback Policy

Borrow CPU RAM to dynamically to expand CUDA Memory Pool. to avoid crashes from fluctuating memory while testing.

medium.com

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Chris Seymour @iiseymour.bsky.social · Apr 1

note: we have upgraded our cuda toolkit version to 12.8 which means our minimum required nvidia driver version is now 525 (up from 475).

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Chris Seymour @iiseymour.bsky.social · Apr 1

Dorado v0.9.5 adds support for Nvidia Blackwell GPUs. Alongside the latest generation, we’ve given Volta & Orin a boost, v5 transformer sup >2X, LSTM hac on Hopper is boosted 20%, dorado correct and polish both receive performance updates, plus a whole bunch more; see..

github.com/nanoporetech...

Release v0.9.5 · nanoporetech/dorado

[0.9.5] (31 March 2025) This release of Dorado delivers significant performance improvements and broader hardware support: Major speed increase of the v5 SUP basecalling models on Volta (7.0) and ...

github.com

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Chris Seymour @iiseymour.bsky.social · Jan 21

Huge performance update in today’s dorado v0.9.1 release on Ampere 8.6/8.7 & Ada Lovelace 8.9 nvidia GPUs with up to 2x increase in throughput with hac calling and 3x sup! 🚀

Plus a whole bunch of updates for dorado polish and the odd misc bug fix.

github.com/nanoporetech...

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Reposted by Chris Seymour

Mike Vella @vellamike.bsky.social · Dec 17

🎄 New Dorado release (v0.9.0) – and it's big!

🚀 Dorado polish command (experimental) for improving draft assemblies – faster & more accurate than Medaka
⚡ Faster modified base calling models
🔧 Usability & accuracy improvements: PolyA, Barcoding, 6mA calling

github.com/nanoporetech...

Release v0.9.0 · nanoporetech/dorado

[0.9.0] (16 Dec 2024) This major release of Dorado introduces several new features and enhancements. The polish command, currently experimental, is optimised for refining draft assemblies of human ...

github.com

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Reposted by Chris Seymour

Mike Vella @vellamike.bsky.social · Nov 27

Exciting news! The latest hifiasm release from Haoyu Cheng and Heng Li adds beta support for @nanoporetech.com simplex R10 reads. Initial results look very promising. 🚀

Check it out: github.com/chhylp123/hi...

Release Hifiasm-0.21.0-r686 · chhylp123/hifiasm

Since Hifiasm-0.20.0 (r639): New Feature: Introduced a beta module for ONT assembly using ONT simplex R10 reads. To enable this feature, add the --ont option as shown below: hifiasm -t64 --ont -o...

github.com

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Reposted by Chris Seymour

Oxford Nanopore @nanoporetech.com · Nov 22

Excited to join the #Nanopore Community on BlueSky.
Follow us for the latest updates and discussions about Oxford Nanopore and Nanopore Community. #WYMM

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