iMeta Science
@imetascience.bsky.social
A Wiley partner journal aims to promote metagenomics and bioinformatics by publishing research articles, reproducible methods, protocols, and reviews.
Pinned
iMeta Science
@imetascience.bsky.social
· Mar 20
Tidyplots empowers life scientists with easy code‐based data visualization
Effective data visualization is vital for analyzing and communicating experimental results. However, most code-based plotting tools require substantial programming experience, posing a significant ba....
onlinelibrary.wiley.com
Tidyplots empowers life scientists with easy code‐based data visualization
onlinelibrary.wiley.com/doi/full/10....
#Bioinformatics #R #Rstudio #visualization
onlinelibrary.wiley.com/doi/full/10....
#Bioinformatics #R #Rstudio #visualization
🌸 Profiling 6423 Chinese women, this study uncovers a midlife shift in the #vaginal #microbiota—
⚖️ Decline of #Lactobacillus crispatus, rise of #Gardnerella vaginalis around age 40.
🧠 A new #microbiome balance score predicts reproductive health risks.
🔗 doi.org/10.1002/imt2...
⚖️ Decline of #Lactobacillus crispatus, rise of #Gardnerella vaginalis around age 40.
🧠 A new #microbiome balance score predicts reproductive health risks.
🔗 doi.org/10.1002/imt2...
Nationwide profiling of vaginal microbiota in Chinese women reveals age‐dependent shifts and predictive biomarkers for reproductive health
The vaginal microbiome is central to reproductive health, yet large-scale studies in East Asian populations remain scarce. Here, we characterized the vaginal microbiota of 6423 Chinese women of repro...
doi.org
October 30, 2025 at 3:24 PM
🌸 Profiling 6423 Chinese women, this study uncovers a midlife shift in the #vaginal #microbiota—
⚖️ Decline of #Lactobacillus crispatus, rise of #Gardnerella vaginalis around age 40.
🧠 A new #microbiome balance score predicts reproductive health risks.
🔗 doi.org/10.1002/imt2...
⚖️ Decline of #Lactobacillus crispatus, rise of #Gardnerella vaginalis around age 40.
🧠 A new #microbiome balance score predicts reproductive health risks.
🔗 doi.org/10.1002/imt2...
🧬 CycloneSEQ #nanopore sequencing rapidly reconstructs multidrug-resistant bacterial genomes!
⚙️ 96.16% read accuracy, 99.98% assembly accuracy.
💡 Complete genomes with just 15× long reads or 5× hybrid data.
🔗 onlinelibrary.wiley.com/doi/10.1002/...
#Bioinformatics #BGI
⚙️ 96.16% read accuracy, 99.98% assembly accuracy.
💡 Complete genomes with just 15× long reads or 5× hybrid data.
🔗 onlinelibrary.wiley.com/doi/10.1002/...
#Bioinformatics #BGI
October 30, 2025 at 3:20 PM
🧬 CycloneSEQ #nanopore sequencing rapidly reconstructs multidrug-resistant bacterial genomes!
⚙️ 96.16% read accuracy, 99.98% assembly accuracy.
💡 Complete genomes with just 15× long reads or 5× hybrid data.
🔗 onlinelibrary.wiley.com/doi/10.1002/...
#Bioinformatics #BGI
⚙️ 96.16% read accuracy, 99.98% assembly accuracy.
💡 Complete genomes with just 15× long reads or 5× hybrid data.
🔗 onlinelibrary.wiley.com/doi/10.1002/...
#Bioinformatics #BGI
🐭 #Lactiplantibacillus plantarum Hi188 promotes post-weaning growth in mice.
🧪 The #metabolite 5-HIAA activates hepatic #AhR, boosting IGF-1 production.
🧑💻 Metagenomic and host transcriptome data reveal that 5-HIAA is co-produced by the host–microbiota axis.
🔗 doi.org/10.1002/imo2...
#microbiome
🧪 The #metabolite 5-HIAA activates hepatic #AhR, boosting IGF-1 production.
🧑💻 Metagenomic and host transcriptome data reveal that 5-HIAA is co-produced by the host–microbiota axis.
🔗 doi.org/10.1002/imo2...
#microbiome
Host–microbiota interaction drives 5‐hydroxyindole‐3‐acetic acid production to promote linear growth in infant mice
This study discovered that Lactiplantibacillus plantarum Hi188 promoted linear growth in postweaning mice. Transcriptomic analysis, untargeted metabolomics, and in vitro experiments showed that the e...
doi.org
October 30, 2025 at 3:06 PM
🐭 #Lactiplantibacillus plantarum Hi188 promotes post-weaning growth in mice.
🧪 The #metabolite 5-HIAA activates hepatic #AhR, boosting IGF-1 production.
🧑💻 Metagenomic and host transcriptome data reveal that 5-HIAA is co-produced by the host–microbiota axis.
🔗 doi.org/10.1002/imo2...
#microbiome
🧪 The #metabolite 5-HIAA activates hepatic #AhR, boosting IGF-1 production.
🧑💻 Metagenomic and host transcriptome data reveal that 5-HIAA is co-produced by the host–microbiota axis.
🔗 doi.org/10.1002/imo2...
#microbiome
🐶💩 Humans and dogs share more than companionship — their gut microbes evolve together!
🧬 Dogs’ gut microbiomes show greater functional similarity to humans than macaques do.
🔗 onlinelibrary.wiley.com/doi/10.1002/...
#microbiome #metabolism
🧬 Dogs’ gut microbiomes show greater functional similarity to humans than macaques do.
🔗 onlinelibrary.wiley.com/doi/10.1002/...
#microbiome #metabolism
Convergent evolution of metabolic functions: Evidence from the gut microbiomes of humans and dogs
Dogs have undergone convergent evolution in their genome with humans in long-term co-living. Studies have shown that the gut microbiomes of dogs exhibit greater similarity to those of humans compared...
onlinelibrary.wiley.com
October 27, 2025 at 3:40 PM
🐶💩 Humans and dogs share more than companionship — their gut microbes evolve together!
🧬 Dogs’ gut microbiomes show greater functional similarity to humans than macaques do.
🔗 onlinelibrary.wiley.com/doi/10.1002/...
#microbiome #metabolism
🧬 Dogs’ gut microbiomes show greater functional similarity to humans than macaques do.
🔗 onlinelibrary.wiley.com/doi/10.1002/...
#microbiome #metabolism
🌟 #iMeta Conference 2025
🧬 Focus: #Microbiology, #medicine, #TCM, #plant science & research talent development
🤝 Empowering innovation & advancing journals globally
🔗 onlinelibrary.wiley.com/doi/10.1002/...
#Bioinformatics #microbiome #metagenomics
🧬 Focus: #Microbiology, #medicine, #TCM, #plant science & research talent development
🤝 Empowering innovation & advancing journals globally
🔗 onlinelibrary.wiley.com/doi/10.1002/...
#Bioinformatics #microbiome #metagenomics
iMeta Conference 2025: Creating high‐impact international journals
The iMeta Conference 2025, part of the iMeta Conference series, themed “Creating High-Impact International Journals,” held at the Huangjiahu Campus of Hubei University of Chinese Medicine from August...
onlinelibrary.wiley.com
October 27, 2025 at 3:28 PM
🌟 #iMeta Conference 2025
🧬 Focus: #Microbiology, #medicine, #TCM, #plant science & research talent development
🤝 Empowering innovation & advancing journals globally
🔗 onlinelibrary.wiley.com/doi/10.1002/...
#Bioinformatics #microbiome #metagenomics
🧬 Focus: #Microbiology, #medicine, #TCM, #plant science & research talent development
🤝 Empowering innovation & advancing journals globally
🔗 onlinelibrary.wiley.com/doi/10.1002/...
#Bioinformatics #microbiome #metagenomics
💥 Can AI solve the #antibiotic resistance crisis?
🤖 By revolutionizing every step of drug discovery—from target ID to lead optimization.
🧬 Two paths: molecular screening & de novo design.
⚙️ #AI accelerates discovery, boosts ADMET prediction & drives multi-target innovation.
🔗 doi.org/10.1002/imm3...
🤖 By revolutionizing every step of drug discovery—from target ID to lead optimization.
🧬 Two paths: molecular screening & de novo design.
⚙️ #AI accelerates discovery, boosts ADMET prediction & drives multi-target innovation.
🔗 doi.org/10.1002/imm3...
Artificial Intelligence Revolutionizes Anti‐Infective Drug Discovery: From Target Identification to Lead Optimization
Artificial intelligence (AI) technology is revolutionizing antimicrobial drug development. In response to increasingly severe antimicrobial resistance challenges, AI can efficiently predict pathogen ...
doi.org
October 27, 2025 at 3:21 PM
💥 Can AI solve the #antibiotic resistance crisis?
🤖 By revolutionizing every step of drug discovery—from target ID to lead optimization.
🧬 Two paths: molecular screening & de novo design.
⚙️ #AI accelerates discovery, boosts ADMET prediction & drives multi-target innovation.
🔗 doi.org/10.1002/imm3...
🤖 By revolutionizing every step of drug discovery—from target ID to lead optimization.
🧬 Two paths: molecular screening & de novo design.
⚙️ #AI accelerates discovery, boosts ADMET prediction & drives multi-target innovation.
🔗 doi.org/10.1002/imm3...
💡 30 scientific recommendations from the #CHINAGUT Conference!
👩🔬 63 experts joined forces to shape the future of:
🦠 #Probiotics
💊 Live biotherapeutic products
💩 #FMT
The goal: standardization, regulation & precision in #microbiome-based therapies.
🔗 doi.org/10.1002/imt2...
👩🔬 63 experts joined forces to shape the future of:
🦠 #Probiotics
💊 Live biotherapeutic products
💩 #FMT
The goal: standardization, regulation & precision in #microbiome-based therapies.
🔗 doi.org/10.1002/imt2...
October 22, 2025 at 3:26 PM
💡 30 scientific recommendations from the #CHINAGUT Conference!
👩🔬 63 experts joined forces to shape the future of:
🦠 #Probiotics
💊 Live biotherapeutic products
💩 #FMT
The goal: standardization, regulation & precision in #microbiome-based therapies.
🔗 doi.org/10.1002/imt2...
👩🔬 63 experts joined forces to shape the future of:
🦠 #Probiotics
💊 Live biotherapeutic products
💩 #FMT
The goal: standardization, regulation & precision in #microbiome-based therapies.
🔗 doi.org/10.1002/imt2...
🍩 What happens when Prmt5 is lost in fat cells?
🧬 Lipid genes go down, #glucose metabolism goes up!
💥 #Triglycerides drop while phospholipid & sphingolipid diversity expands.
PRMT5 emerges as a key regulator of membrane transport & #cholesterol synthesis.
🔗 doi.org/10.1002/imo2...
🧬 Lipid genes go down, #glucose metabolism goes up!
💥 #Triglycerides drop while phospholipid & sphingolipid diversity expands.
PRMT5 emerges as a key regulator of membrane transport & #cholesterol synthesis.
🔗 doi.org/10.1002/imo2...
Multiomics analyses reveal that PRMT5 regulates membrane transport and cholesterol synthesis in white adipocytes
Prmt5AKO downregulates genes related to fatty acid transport and triacylglycerol synthesis, while upregulating genes involved in glucose transport and cholesterol biogenesis. These changes cause alte...
doi.org
October 22, 2025 at 3:22 PM
🍩 What happens when Prmt5 is lost in fat cells?
🧬 Lipid genes go down, #glucose metabolism goes up!
💥 #Triglycerides drop while phospholipid & sphingolipid diversity expands.
PRMT5 emerges as a key regulator of membrane transport & #cholesterol synthesis.
🔗 doi.org/10.1002/imo2...
🧬 Lipid genes go down, #glucose metabolism goes up!
💥 #Triglycerides drop while phospholipid & sphingolipid diversity expands.
PRMT5 emerges as a key regulator of membrane transport & #cholesterol synthesis.
🔗 doi.org/10.1002/imo2...
Reposted by iMeta Science
Yongxin introduces numerous methods published in iMeta @imetascience.bsky.social
#BGIspatialmicrobiome
#BGIspatialmicrobiome
October 22, 2025 at 3:24 AM
Yongxin introduces numerous methods published in iMeta @imetascience.bsky.social
#BGIspatialmicrobiome
#BGIspatialmicrobiome
🌱 What shapes the chemotypes of Atractylodes lancea?
Not genes alone!
🧬 Genetic divergence follows altitude & climate.
🌾 #Soil and #microbiome together tune its metabolite profiles.
🦠 Core #rhizosphere & endophytic microbes hold the key.
🔗 doi.org/10.1002/imo2...
Not genes alone!
🧬 Genetic divergence follows altitude & climate.
🌾 #Soil and #microbiome together tune its metabolite profiles.
🦠 Core #rhizosphere & endophytic microbes hold the key.
🔗 doi.org/10.1002/imo2...
The combined influence of microbiome and soil environment contributes to the chemotype differentiation in Atractylodes lancea
Genetic differentiation between the Maoshan-Dabie Mountains group (MA genotype) and Qinling-Taihang Mountains group (SA genotype) of Atractylodes lancea occurs along altitude and climatic gradients. ....
doi.org
October 22, 2025 at 3:08 PM
🌱 What shapes the chemotypes of Atractylodes lancea?
Not genes alone!
🧬 Genetic divergence follows altitude & climate.
🌾 #Soil and #microbiome together tune its metabolite profiles.
🦠 Core #rhizosphere & endophytic microbes hold the key.
🔗 doi.org/10.1002/imo2...
Not genes alone!
🧬 Genetic divergence follows altitude & climate.
🌾 #Soil and #microbiome together tune its metabolite profiles.
🦠 Core #rhizosphere & endophytic microbes hold the key.
🔗 doi.org/10.1002/imo2...
🫀 Can plant sterols fight #atherosclerosis?
✅ Yes! #Stigmasterol reduces inflammatory macrophages & foam cells.
💡 It boosts cholesterol efflux, blocks ox-LDL uptake, and modulates AMPK/NF-κB/NLRP3 signaling.
📉 The result: less vascular #inflammation, healthier arteries.
🔗 doi.org/10.1002/imo2...
✅ Yes! #Stigmasterol reduces inflammatory macrophages & foam cells.
💡 It boosts cholesterol efflux, blocks ox-LDL uptake, and modulates AMPK/NF-κB/NLRP3 signaling.
📉 The result: less vascular #inflammation, healthier arteries.
🔗 doi.org/10.1002/imo2...
Stigmasterol attenuates atherosclerosis by inhibiting inflammatory signaling and foam cell formation
Stigmasterol mitigates atherosclerotic plaque formation by modulating foam cell phenotypic alterations and cholesterol metabolism. Stigmasterol inhibits inflammatory CD86+ macrophage polarization via...
doi.org
October 21, 2025 at 2:29 PM
🫀 Can plant sterols fight #atherosclerosis?
✅ Yes! #Stigmasterol reduces inflammatory macrophages & foam cells.
💡 It boosts cholesterol efflux, blocks ox-LDL uptake, and modulates AMPK/NF-κB/NLRP3 signaling.
📉 The result: less vascular #inflammation, healthier arteries.
🔗 doi.org/10.1002/imo2...
✅ Yes! #Stigmasterol reduces inflammatory macrophages & foam cells.
💡 It boosts cholesterol efflux, blocks ox-LDL uptake, and modulates AMPK/NF-κB/NLRP3 signaling.
📉 The result: less vascular #inflammation, healthier arteries.
🔗 doi.org/10.1002/imo2...
🧬 New insights into the diversity of #CRISPR–Cas systems!
#Metagenomic analyses uncovered 4,112 Cas12 proteins and 6 novel subtypes.
🤖 #AI-based Cas12fam annotates 18 domains.
🌿 Cas12 subtypes show habitat-specific enrichment.
🔗 doi.org/10.1002/imo2...
#microbiome #metagenomics #bioinformatics
#Metagenomic analyses uncovered 4,112 Cas12 proteins and 6 novel subtypes.
🤖 #AI-based Cas12fam annotates 18 domains.
🌿 Cas12 subtypes show habitat-specific enrichment.
🔗 doi.org/10.1002/imo2...
#microbiome #metagenomics #bioinformatics
Metagenomic mining reveals novel Cas12 subtypes and their evolutionary diversification
We identified 4112 Cas12 Proteins and 6 new Cas12 subtypes, revealed their significant diversity in N-terminal regions, repeat sequences, and sequences motifs. We developed an AI-driven algorithm, Ca...
onlinelibrary.wiley.com
October 21, 2025 at 2:25 PM
🧬 New insights into the diversity of #CRISPR–Cas systems!
#Metagenomic analyses uncovered 4,112 Cas12 proteins and 6 novel subtypes.
🤖 #AI-based Cas12fam annotates 18 domains.
🌿 Cas12 subtypes show habitat-specific enrichment.
🔗 doi.org/10.1002/imo2...
#microbiome #metagenomics #bioinformatics
#Metagenomic analyses uncovered 4,112 Cas12 proteins and 6 novel subtypes.
🤖 #AI-based Cas12fam annotates 18 domains.
🌿 Cas12 subtypes show habitat-specific enrichment.
🔗 doi.org/10.1002/imo2...
#microbiome #metagenomics #bioinformatics
🚀 #iMeta is reshaping academic communication!
📲 Multi-platform + bilingual strategy expands global reach.
📈 1.36M full-text downloads, >10K citations, IF 33.2 (2024)!
🌐 New sub-journals & events foster a vibrant research ecosystem.
🔗 doi.org/10.1002/imt2...
#Journal
📲 Multi-platform + bilingual strategy expands global reach.
📈 1.36M full-text downloads, >10K citations, IF 33.2 (2024)!
🌐 New sub-journals & events foster a vibrant research ecosystem.
🔗 doi.org/10.1002/imt2...
#Journal
iMeta: Boosting academic sharing and collaboration via social media
Social media platforms have revolutionized scientific communication by bridging gaps between researchers, academic journals, and global audiences. This article showcases iMeta, an open-access journal...
doi.org
October 21, 2025 at 2:15 PM
🚀 #iMeta is reshaping academic communication!
📲 Multi-platform + bilingual strategy expands global reach.
📈 1.36M full-text downloads, >10K citations, IF 33.2 (2024)!
🌐 New sub-journals & events foster a vibrant research ecosystem.
🔗 doi.org/10.1002/imt2...
#Journal
📲 Multi-platform + bilingual strategy expands global reach.
📈 1.36M full-text downloads, >10K citations, IF 33.2 (2024)!
🌐 New sub-journals & events foster a vibrant research ecosystem.
🔗 doi.org/10.1002/imt2...
#Journal
Abnormal membrane potentials & ion channel signatures drive #tumor growth, metastasis & immune evasion
💊 Ion channel drugs, tumor-treating fields & nano-delivery offer new precision therapies
🧠 Electro-immunotherapy reshapes the TME
🔗 doi.org/10.1002/imm3...
#CancerResearch #Immunotherapy
💊 Ion channel drugs, tumor-treating fields & nano-delivery offer new precision therapies
🧠 Electro-immunotherapy reshapes the TME
🔗 doi.org/10.1002/imm3...
#CancerResearch #Immunotherapy
Tumor Electrophysiology in Precision Tumor Therapy
This review highlights tumor electrophysiological hallmarks as therapeutic targets in precision oncology. We examine how membrane potential alterations and ion channel fingerprints drive malignancy, ...
doi.org
October 19, 2025 at 3:18 PM
Abnormal membrane potentials & ion channel signatures drive #tumor growth, metastasis & immune evasion
💊 Ion channel drugs, tumor-treating fields & nano-delivery offer new precision therapies
🧠 Electro-immunotherapy reshapes the TME
🔗 doi.org/10.1002/imm3...
#CancerResearch #Immunotherapy
💊 Ion channel drugs, tumor-treating fields & nano-delivery offer new precision therapies
🧠 Electro-immunotherapy reshapes the TME
🔗 doi.org/10.1002/imm3...
#CancerResearch #Immunotherapy
🧬 Benchmarking 14 spatial clustering methods across ~600 #SpatialTranscriptomics datasets
🧫 10 technologies, 8 organs — consistent insights
⚙️ Clear guidance for method choice & preprocessing
🔗 doi.org/10.1002/imt2...
#Bioinformatics #SpatialOmics #scRNA
🧫 10 technologies, 8 organs — consistent insights
⚙️ Clear guidance for method choice & preprocessing
🔗 doi.org/10.1002/imt2...
#Bioinformatics #SpatialOmics #scRNA
A comprehensive benchmarking for spatially resolved transcriptomics clustering methods across variable technologies, organs, and replicates
Spatial clustering is a critical step in spatially resolved transcriptomics. Here, we conducted a comprehensive benchmarking analysis of 14 spatial clustering methods using ~600 datasets, including b...
doi.org
October 19, 2025 at 3:14 PM
🧬 Benchmarking 14 spatial clustering methods across ~600 #SpatialTranscriptomics datasets
🧫 10 technologies, 8 organs — consistent insights
⚙️ Clear guidance for method choice & preprocessing
🔗 doi.org/10.1002/imt2...
#Bioinformatics #SpatialOmics #scRNA
🧫 10 technologies, 8 organs — consistent insights
⚙️ Clear guidance for method choice & preprocessing
🔗 doi.org/10.1002/imt2...
#Bioinformatics #SpatialOmics #scRNA
🌏 #Soil pH shapes microbial #nitrogen cycling in Japanese forests 🌲
🧪 Acidic soils host stress-tolerant microbes retaining N
⚙️ Neutral soils favor energy-efficient taxa releasing #ammonium & driving #nitrification
🔗 doi.org/10.1002/imo2...
#SoilHealth #Microbiome #metabolism
🧪 Acidic soils host stress-tolerant microbes retaining N
⚙️ Neutral soils favor energy-efficient taxa releasing #ammonium & driving #nitrification
🔗 doi.org/10.1002/imo2...
#SoilHealth #Microbiome #metabolism
Soil pH modulates microbial nitrogen allocation in soil via compositional and metabolic shifts across forests in Japan
This study reveals how soil pH regulates microbial N allocation in forest soils across Japan. We show that microbial abundance controls the overall rate of N cycling, while microbial composition and ...
doi.org
October 19, 2025 at 3:06 PM
🌏 #Soil pH shapes microbial #nitrogen cycling in Japanese forests 🌲
🧪 Acidic soils host stress-tolerant microbes retaining N
⚙️ Neutral soils favor energy-efficient taxa releasing #ammonium & driving #nitrification
🔗 doi.org/10.1002/imo2...
#SoilHealth #Microbiome #metabolism
🧪 Acidic soils host stress-tolerant microbes retaining N
⚙️ Neutral soils favor energy-efficient taxa releasing #ammonium & driving #nitrification
🔗 doi.org/10.1002/imo2...
#SoilHealth #Microbiome #metabolism
🧩 New insights into the #gut–#brain axis:
🦠L-lysine boosts barrier function & eases anxiety via tryptophan metabolism
😟H. biformis strengthens the barrier but worsens #anxiety
💻Multi-omics reveal lysine degradation as a key mechanism
🔗 doi.org/10.1002/imo2...
#microbiome #Bioinformatics
🦠L-lysine boosts barrier function & eases anxiety via tryptophan metabolism
😟H. biformis strengthens the barrier but worsens #anxiety
💻Multi-omics reveal lysine degradation as a key mechanism
🔗 doi.org/10.1002/imo2...
#microbiome #Bioinformatics
A reciprocal interaction between L‐lysine and Holdemanella biformis modulates intestinal barrier function and anxiety in irritable bowel syndrome
This study uncovers a complex interaction between l-lysine and Holdemanella biformis (H. biformis) in irritable bowel syndrome (IBS). l-lysine enhances intestinal barrier function and alleviates anxi....
doi.org
September 26, 2025 at 3:59 PM
🧩 New insights into the #gut–#brain axis:
🦠L-lysine boosts barrier function & eases anxiety via tryptophan metabolism
😟H. biformis strengthens the barrier but worsens #anxiety
💻Multi-omics reveal lysine degradation as a key mechanism
🔗 doi.org/10.1002/imo2...
#microbiome #Bioinformatics
🦠L-lysine boosts barrier function & eases anxiety via tryptophan metabolism
😟H. biformis strengthens the barrier but worsens #anxiety
💻Multi-omics reveal lysine degradation as a key mechanism
🔗 doi.org/10.1002/imo2...
#microbiome #Bioinformatics
🚀 317 R scripts for biomedical research, no coding barrier
⏱️ Standardized design saves time
✅ Verified, annotated, reproducible
🧬 Covers #scRNA-seq, spatial #transcriptomics, #ML & more
🔗 doi.org/10.1002/imm3...
#Bioinformatics
⏱️ Standardized design saves time
✅ Verified, annotated, reproducible
🧬 Covers #scRNA-seq, spatial #transcriptomics, #ML & more
🔗 doi.org/10.1002/imm3...
#Bioinformatics
FigureYa: A Standardized Visualization Framework for Enhancing Biomedical Data Interpretation and Research Efficiency
FigureYa integrates 317 visualization tools across diverse biomedical domains, categorized by research type, analytical method, and output format. This resource streamlines data interpretation and en...
doi.org
September 22, 2025 at 3:29 PM
🚀 317 R scripts for biomedical research, no coding barrier
⏱️ Standardized design saves time
✅ Verified, annotated, reproducible
🧬 Covers #scRNA-seq, spatial #transcriptomics, #ML & more
🔗 doi.org/10.1002/imm3...
#Bioinformatics
⏱️ Standardized design saves time
✅ Verified, annotated, reproducible
🧬 Covers #scRNA-seq, spatial #transcriptomics, #ML & more
🔗 doi.org/10.1002/imm3...
#Bioinformatics
🫀🦠 Gut–heart axis in #CAD: distinct microbial & metabolic shifts across normal, sCAD & ACS;
ACS signatures partly reversible.
Multi-omics #ML outperforms clinical risk factors in stratifying CAD subtypes.
🔗 onlinelibrary.wiley.com/doi/10.1002/... #microbiome
ACS signatures partly reversible.
Multi-omics #ML outperforms clinical risk factors in stratifying CAD subtypes.
🔗 onlinelibrary.wiley.com/doi/10.1002/... #microbiome
onlinelibrary.wiley.com
September 20, 2025 at 3:53 AM
🫀🦠 Gut–heart axis in #CAD: distinct microbial & metabolic shifts across normal, sCAD & ACS;
ACS signatures partly reversible.
Multi-omics #ML outperforms clinical risk factors in stratifying CAD subtypes.
🔗 onlinelibrary.wiley.com/doi/10.1002/... #microbiome
ACS signatures partly reversible.
Multi-omics #ML outperforms clinical risk factors in stratifying CAD subtypes.
🔗 onlinelibrary.wiley.com/doi/10.1002/... #microbiome
🦠 #Lactobacillus johnsonii-FM1 fights colorectal #cancer:
🌱 Restoring gut diversity & barrier integrity
🔬 Producing VCA via vanillin dehydrogenase
❌ VCA blocks #CRC cell growth & Wnt/β-catenin signaling
👉 A gut microbe–metabolite axis for anti-CRC therapy.
🔗 onlinelibrary.wiley.com/doi/10.1002/...
🌱 Restoring gut diversity & barrier integrity
🔬 Producing VCA via vanillin dehydrogenase
❌ VCA blocks #CRC cell growth & Wnt/β-catenin signaling
👉 A gut microbe–metabolite axis for anti-CRC therapy.
🔗 onlinelibrary.wiley.com/doi/10.1002/...
Lactobacillus johnsonii‐FM1 modulates gut microbiota and secretes anticancer metabolite vanillic acid to inhibit colorectal tumorigenesis
Lactobacillus johnsonii-FM1 alleviates colorectal tumorigenesis in both ApcMin/+ and azoxymethane/dextran sulfate sodium mouse models by enriching beneficial gut microbiota, restoring epithelial barr...
onlinelibrary.wiley.com
September 17, 2025 at 3:36 PM
🦠 #Lactobacillus johnsonii-FM1 fights colorectal #cancer:
🌱 Restoring gut diversity & barrier integrity
🔬 Producing VCA via vanillin dehydrogenase
❌ VCA blocks #CRC cell growth & Wnt/β-catenin signaling
👉 A gut microbe–metabolite axis for anti-CRC therapy.
🔗 onlinelibrary.wiley.com/doi/10.1002/...
🌱 Restoring gut diversity & barrier integrity
🔬 Producing VCA via vanillin dehydrogenase
❌ VCA blocks #CRC cell growth & Wnt/β-catenin signaling
👉 A gut microbe–metabolite axis for anti-CRC therapy.
🔗 onlinelibrary.wiley.com/doi/10.1002/...
🚀 #fastp: ultra-fast, full-featured & user-friendly #FASTQ preprocessing tool!
☁️ Cloud-friendly, minimal resources, web-based reports
📊 v1.0 brings enhanced HTML reporting & parallel batch processing
onlinelibrary.wiley.com/doi/10.1002/...
#Bioinformatics #NGS #sequencing
☁️ Cloud-friendly, minimal resources, web-based reports
📊 v1.0 brings enhanced HTML reporting & parallel batch processing
onlinelibrary.wiley.com/doi/10.1002/...
#Bioinformatics #NGS #sequencing
fastp 1.0: An ultra‐fast all‐round tool for FASTQ data quality control and preprocessing
The figure shows side-by-side quality comparison of the data before and after preprocessing using fastp 1.0. As can be seen from this figure, the data quality has been significantly improved after fa...
onlinelibrary.wiley.com
September 15, 2025 at 3:15 PM
🚀 #fastp: ultra-fast, full-featured & user-friendly #FASTQ preprocessing tool!
☁️ Cloud-friendly, minimal resources, web-based reports
📊 v1.0 brings enhanced HTML reporting & parallel batch processing
onlinelibrary.wiley.com/doi/10.1002/...
#Bioinformatics #NGS #sequencing
☁️ Cloud-friendly, minimal resources, web-based reports
📊 v1.0 brings enhanced HTML reporting & parallel batch processing
onlinelibrary.wiley.com/doi/10.1002/...
#Bioinformatics #NGS #sequencing
🌍 New study on hypervirulent #Klebsiella pneumoniae (CC23-K1):
🔹 Geographic distance drives global spread patterns
🔹 >130 gain/loss events show unstable carbapenem resistance
🔹 KPC/NDM (Asia) conflict with #virulence, OXA-48 (Europe) better preserves it
🔗 onlinelibrary.wiley.com/doi/10.1002/...
🔹 Geographic distance drives global spread patterns
🔹 >130 gain/loss events show unstable carbapenem resistance
🔹 KPC/NDM (Asia) conflict with #virulence, OXA-48 (Europe) better preserves it
🔗 onlinelibrary.wiley.com/doi/10.1002/...
Geographic containment and virulence‐resistance trade‐offs drive the evolution of hypervirulent Klebsiella pneumoniae
The global emergence of hypervirulent, carbapenem-resistant Klebsiella pneumoniae (hvCRKP) poses a paradox: why do such dangerous clones remain geographically confined? By analyzing over 2500 CC23 ge...
onlinelibrary.wiley.com
September 13, 2025 at 3:22 PM
🌍 New study on hypervirulent #Klebsiella pneumoniae (CC23-K1):
🔹 Geographic distance drives global spread patterns
🔹 >130 gain/loss events show unstable carbapenem resistance
🔹 KPC/NDM (Asia) conflict with #virulence, OXA-48 (Europe) better preserves it
🔗 onlinelibrary.wiley.com/doi/10.1002/...
🔹 Geographic distance drives global spread patterns
🔹 >130 gain/loss events show unstable carbapenem resistance
🔹 KPC/NDM (Asia) conflict with #virulence, OXA-48 (Europe) better preserves it
🔗 onlinelibrary.wiley.com/doi/10.1002/...
🚀SCTP, a deep fusion model of #scRNA-seq, spatial & phenotypic #transcriptomics, quantifies #CRC malignancy with high accuracy.
✅ Detects subregions & warning genes missed by pathology
✅ SCTP-CRC generalizes to liver mets, validates #MUC2 biomarker
🔗 onlinelibrary.wiley.com/doi/10.1002/...
#cancer
✅ Detects subregions & warning genes missed by pathology
✅ SCTP-CRC generalizes to liver mets, validates #MUC2 biomarker
🔗 onlinelibrary.wiley.com/doi/10.1002/...
#cancer
September 12, 2025 at 2:58 PM
🚀SCTP, a deep fusion model of #scRNA-seq, spatial & phenotypic #transcriptomics, quantifies #CRC malignancy with high accuracy.
✅ Detects subregions & warning genes missed by pathology
✅ SCTP-CRC generalizes to liver mets, validates #MUC2 biomarker
🔗 onlinelibrary.wiley.com/doi/10.1002/...
#cancer
✅ Detects subregions & warning genes missed by pathology
✅ SCTP-CRC generalizes to liver mets, validates #MUC2 biomarker
🔗 onlinelibrary.wiley.com/doi/10.1002/...
#cancer
🌐 Meet GISDD — an #AI-powered #Bioinformatics platform for fast dengue virus (DENV) genotyping & tracing.
Upload your sequence ➡️ get instant genotype, origin & risk insights.
Supporting global DENV surveillance & collaboration.
#DENV #Genomics #PublicHealth onlinelibrary.wiley.com/doi/10.1002/...
Upload your sequence ➡️ get instant genotype, origin & risk insights.
Supporting global DENV surveillance & collaboration.
#DENV #Genomics #PublicHealth onlinelibrary.wiley.com/doi/10.1002/...
GISDD: A comprehensive global integrated sequence and genotyping database platform for dengue virus, facilitating a stratified coordinated surveillance strategy
GISDD, the Global Integrated Sequence and Genotyping Database for Dengue Virus (DENV), provides an integrated online analysis platform encompassing tools such as GISDDrlearn, GISDDprimer, and GISDDre...
onlinelibrary.wiley.com
September 11, 2025 at 3:13 PM
🌐 Meet GISDD — an #AI-powered #Bioinformatics platform for fast dengue virus (DENV) genotyping & tracing.
Upload your sequence ➡️ get instant genotype, origin & risk insights.
Supporting global DENV surveillance & collaboration.
#DENV #Genomics #PublicHealth onlinelibrary.wiley.com/doi/10.1002/...
Upload your sequence ➡️ get instant genotype, origin & risk insights.
Supporting global DENV surveillance & collaboration.
#DENV #Genomics #PublicHealth onlinelibrary.wiley.com/doi/10.1002/...
🚀 PSOSP predicts #prophage induction!
From 49,333 genomes, we uncovered 11,806 SiPs, showing unique genomic/host traits and hinting at SiP–SdP interconversion.
onlinelibrary.wiley.com/doi/10.1002/...
Available: vee-lab.sjtu.edu.cn/PSOSP/
#Bioinformatics #microbiome
From 49,333 genomes, we uncovered 11,806 SiPs, showing unique genomic/host traits and hinting at SiP–SdP interconversion.
onlinelibrary.wiley.com/doi/10.1002/...
Available: vee-lab.sjtu.edu.cn/PSOSP/
#Bioinformatics #microbiome
PSOSP uncovers pervasive SOS‐independent prophages with distinct genomic and host traits in bacterial genomes
Prophages are ubiquitously present in bacterial genomes, significantly influencing host physiological and ecological functions. We present Prophage SOS-dependency Predictor (PSOSP), a novel bioinform...
onlinelibrary.wiley.com
September 11, 2025 at 3:12 PM
🚀 PSOSP predicts #prophage induction!
From 49,333 genomes, we uncovered 11,806 SiPs, showing unique genomic/host traits and hinting at SiP–SdP interconversion.
onlinelibrary.wiley.com/doi/10.1002/...
Available: vee-lab.sjtu.edu.cn/PSOSP/
#Bioinformatics #microbiome
From 49,333 genomes, we uncovered 11,806 SiPs, showing unique genomic/host traits and hinting at SiP–SdP interconversion.
onlinelibrary.wiley.com/doi/10.1002/...
Available: vee-lab.sjtu.edu.cn/PSOSP/
#Bioinformatics #microbiome