IMMERGE MSCA DN
@immerge.bsky.social
200 followers 640 following 24 posts
IMMERGE is a #MSCA Doctoral Network (DN) coordinated by @carrerasijc.bsky.social. Storming Immune Monogenic Conditions through multiomic and gene editing approaches (GA 101119927). ➡️ www.immergeproject.eu
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immerge.bsky.social
🌍 IMMERGE beyond the lab!

On Sept 20, @angelopilotti.bsky.social (Pierre's lab) spoke at a conference in Fondi, Italy—organized by local associations to bring science closer to the public.

👏 He talked about autoimmune diseases & shared PhD insights on stress responses and immunity

#IMMERGE #MSCA
immerge.bsky.social
🌟#IMMERGE 2025 PI spotlight!
@dimiccolab.bsky.social at OSR reveals how CRISPR-Cas9 in HSCs can trigger senescence-like responses, & provides optimized protocols to preserve edited cells long-term!

1️⃣ pubmed.ncbi.nlm.nih.gov/40466639/
2️⃣ pubmed.ncbi.nlm.nih.gov/40173037/

More highlights coming soon🚀
immerge.bsky.social
👏 Proud moment for #IMMERGE! Our DC7 fellow Hanna Norbäck co-chaired a session at the 2025 DBM Summer Symposium (@unibas.ch) together with Dr. Zaugg. 🌟
A great day of science, collaboration & inspiring talks! 🧪🔬

#DBMSymposium2025 #TeamDBM #AcademicLife #Science #IMMERGE
immerge.bsky.social
🌟 #IMMERGE 2025 PI spotlight: Prof. Warnatz on immunodeficiencies!

Exploring T & B cell changes, unique glycosylation, & risk factors for premature mortality:

1️⃣ pubmed.ncbi.nlm.nih.gov/40496855/
2️⃣ pubmed.ncbi.nlm.nih.gov/40090481/
3️⃣ pubmed.ncbi.nlm.nih.gov/40013136/

More highlights coming soon!🚀
immerge.bsky.social
New paper alert – now in @ScienceAdvances

Congrats to IMMERGE PI José Luís Sardina and team!🎉
This study shows how targeted DNA methylation editing at a key immune gene can reshape cell fate and immune responses.

📷 Read more: pubmed.ncbi.nlm.nih.gov/40668918/
#IMMERGE #MSCA #CRISPR #epigenetics
immerge.bsky.social
🧬 New in Nature Methods!

Congrats to IMMERGE PI Judith Zaugg and team on SUM-seq—a new ultra-high-throughput multiplexed sequencing for profiling chromatin accessibility & gene expression in single nuclei. Tested in macrophages, T cells & iPSCs!

📖 Find out more: tinylink.net/a3PNE
#IMMERGE #MSCA
Single-cell ultra-high-throughput multiplexed chromatin and RNA profiling reveals gene regulatory dynamics - Nature Methods
This work presents SUM-seq, an ultra-high-throughput method for co-profiling chromatin accessibility and gene expression in single nuclei across multiplexed samples, advancing the study of gene regula...
doi.org
immerge.bsky.social
🚨PhD Opportunity Alert!

The second NUCLEAR network recruitment call is now open!
Don’t miss out!

#PhD #MSCA #NUCLEARnetwork #GeneRegulation #ScientificCareers #HorizonEurope #EUresearch #Immunology
nucleardn.bsky.social
🚨 2nd Recruitment call is now open! 🚨

⚠️There are still 3 Doctoral Candidate positions available in NUCLEAR! Don't miss this oportunity!

If you're ready to dive into innovative research in metabolic regulation of genome, join our international program.

📩Apply now: nuclear-dn.eu/recruitment/
immerge.bsky.social
🚀The IMMERGE consortium met in Heidelberg for our 2nd training event & Midterm Review!

DCs joined sessions on:
🔬Epigenetic & Transcriptional Regulation
🧠Leadership & Management

Huge thanks to all involved—and to @embl.org for hosting us!

🌍Next stop: Milan!
👉 immergeproject.eu

#IMMERGE #MSCA
Reposted by IMMERGE MSCA DN
eballestar.bsky.social
Busy and inspiring week at @embl.org for the @immerge.bsky.social midterm review and two great workshops: #Epigenetics & #TranscriptionalRegulation, and #Leadership & #Management. Grateful for the science, the insights, and everyone’s commitment !
Reposted by IMMERGE MSCA DN
angelopilotti.bsky.social
🔵New paper alert🔵

❗️Barros and Ferreira show that induction of the ISR by SubAB drives type-I IFN expression in pDCs via STING

🎉Glad to have contributed to this work.
Thanks to Philippe Pierre and @immerge.bsky.social

👉🏻Full article on @pnas.org at www.pnas.org/doi/10.1073/pnas.2421258122
immerge.bsky.social
🔬 Meet the Researchers Behind IMMERGE! 🔬

This week: Renata Chalupska & Dr. Saka from @embl.org 🧬
Renata investigates how immune monogenic syndromes impact blood cell development.

That’s a wrap on our IMMERGE series—13 brilliant researchers shaping immunology’s future! 🌍👏

#IMMERGE #MSCA #IEI
immerge.bsky.social
🔬 Meet the Researchers Behind IMMERGE!🔬

This week: Martí Leira & Dr. Vento-Tormo from @sangerinstitute.bsky.social!🧬
Martí explores novel regulators of Tregopathies to better understand immune dysregulation and its roots.

Stay tuned for more IMMERGE scientists! 🚀

#IMMERGE #MSCA #IEI
immerge.bsky.social
🔬 Meet the Researchers Behind IMMERGE! 🔬

This week: Eric O'Shee & Dr. Geiger from IRB! 🧪✨
Eric studies how mutations linked to Treg dysfunction impair immune suppression, disrupt immune tolerance, and contributing to autoimmunity.

Stay tuned for more IMMERGE scientists! 🚀

#IMMERGE #MSCA #Tregs
immerge.bsky.social
🔬 Meet the Researchers Behind IMMERGE! 🔬

This week: Franka Witthauer & Dr. Casini from Alia Therapeutics! ✨
Franka works on correcting mutations linked to primary immunodeficiencies using innovative, engineered CRISPR tools.👩‍🔬

Stay tuned for more IMMERGE scientists! 🚀

#IMMERGE #MSCA #IEI #CRISPR
Reposted by IMMERGE MSCA DN
carrerasleaders.bsky.social
📢Looking for a #postdoc in blood cancers?

The CarrerasLeaders Call 4 is OPEN for exceptional applicants at @carrerasijc.bsky.social.

📅 Apply by June 1, 2025

✨World-class researchers supervision
✨International secondments
✨Top-tier research infrastructures

More details at carrerasleaders.eu
immerge.bsky.social
🔬 Meet the Researchers Behind IMMERGE! 🔬

This week: Tharaa Mohammad & Dr. Rodriguez from qGenomics! 🧬
Tharaa studies how JAK/STAT and NF-κB signaling contribute to immune-related preeclampsia, uncovering maternal-fetal immune dynamics.

Stay tuned for more IMMERGE scientists! 🚀

#IMMERGE #MSCA #IEI
immerge.bsky.social
🔬 Meet the Researchers Behind IMMERGE! 🔬

This week: Florence Melbert, @eballestar.bsky.social & @jlsardinalab.bsky.social from @carrerasijc.bsky.social!
Florence is studying how IKAROS mutations contribute to IEI.👩‍🔬

Stay tuned for more IMMERGE scientists! 🚀

#IMMERGE #MSCA #IEI #IKAROS
immerge.bsky.social
🔬 Meet the Researchers Behind IMMERGE! 🔬

This week: Hanna Norbäck & Dr. Zaugg from @unibas.ch
Hanna is developing a framework to map cell-type-specific mutation effects, enhancing our understanding of immune dysregulation.

Stay tuned for more IMMERGE scientists! 🚀

#IMMERGE #MSCA #IEI
immerge.bsky.social
🧬 New Review Alert!

Dr. Boisson-Dupuis just published this review on how monogenic inborn errors of immunity shape susceptibility to infectious diseases, shedding light on key immune defense mechanisms. A must-read for immunologists!
👉 tinyurl.com/27av65jh

#IEI #Immunology #InfectiousDiseases
The monogenic landscape of human infectious diseases
The spectrum of known monogenic inborn errors of immunity is growing, with certain disorders underlying a specific and narrow range of infectious dise…
tinyurl.com
immerge.bsky.social
🔬 Meet the Researchers Behind IMMERGE! 🔬

This week: Andrea Carpinteiro & Dr. Di Micco from OSR! 🧬
Andrea explores how dysfunctional telomeres impact stem cells & immunity, revealing links between aging and immune regulation.

Stay tuned for more IMMERGE scientists! 🚀

#IMMERGE #MSCA #IEI #Telomeres
immerge.bsky.social
🔬 Meet the Researchers Behind IMMERGE!🔬

This week: Laura Artal & Dr. Klaus Warnatz from @uni-freiburg.de! Laura will focus on IKBKB deficiency, aiming to uncover its impact on patients with immunodeficiencies 🧬✨

Stay tuned for more IMMERGE scientists! 🚀

#IMMERGE #MSCA #IEI #Immunology #IKBKB
immerge.bsky.social
🔬Exciting IMMERGE research in action! 🔬

IMMERGE PhD fellow @angelopilotti.bsky.social presented his work at the PhD workshop at @ciml.bsky.social! 📊✨

Great to see our researchers sharing knowledge & advancing the field! 👏

#IMMERGE #MSCA #IEI #Immunology #ISR #DendriticCells #SLE #SAVI
angelopilotti.bsky.social
🔬 Exploring the role of the Integrated Stress Response in dendritic cells and interferonopathies 🔬

📊Last week, I had the opportunity of presenting my research project during the PhD workshop at @ciml.bsky.social. (1/7)
immerge.bsky.social
🔬 Meet the Researchers Behind IMMERGE! 🔬

This week: Giulia Bressan & Dr. Bodo Grimbacher from @uni-freiburg.de!
Giulia will dive into STAT3 regulation & signaling to better understand immune function👩‍🔬🌟

Stay tuned for more IMMERGE scientists! 🚀

#IMMERGE #MSCA #IEI #Immunology #STAT3
Reposted by IMMERGE MSCA DN
scinews.bsky.social
Drawing inspiration from the tardigrade, researchers developed a new strategy that may protect cancer patients from the side effects of radiation therapy.

www.nature.com/articles/s41...
immerge.bsky.social
🔬 Meet the Researchers Behind IMMERGE! 🔬

This week: @angelopilotti.bsky.social & Dr. Pierre from @cnrs.fr!
Angelo will study the functional impact of EIF2AK mutants in dendritic cells & interferonopathies🧬👨‍🔬

Stay tuned for more IMMERGE scientists! 🚀

#IMMERGE #MSCA #IEI #DCs #Interferonopathies