ImmunoSketch
@immunosketch.bsky.social
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30-sec immunology news, delivered daily. No scientific knowledge necessary, built for everyone. #ImmunoSky
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immunosketch.bsky.social
A starter pack for PhD students and Postdocs in Immunology to connect 🔽

Drop a 🧬 and I'll add you to the list.
Let's build the upcoming immuno community!

#ImmunoSky 🧪

go.bsky.app/RABVXY4
Reposted by ImmunoSketch
immunosketch.bsky.social
A starter pack for PhD students and Postdocs in Immunology to connect 🔽

Drop a 🧬 and I'll add you to the list.
Let's build the upcoming immuno community!

#ImmunoSky 🧪

go.bsky.app/RABVXY4
immunosketch.bsky.social
#Preprints start the conversation, and #PeerReview pushes research forward. That’s how every discovery we illustrate here takes shape.

Our friends over at The Modern Peer are breaking it all down—check out their blog!
www.themodernpeer.com

#AcademicSky #PhDSky #SciPub #SciComm #AcademicChatter 🧪
the modern peer
academic publishing: unfiltered and uncensored.
www.themodernpeer.com
immunosketch.bsky.social
This concludes our 10-day journey and the ImmunoSketch adventure. Thank you for joining in.
May your new year be as resilient and adaptive as the cells we study.
Happy new year! 🎄
immunosketch.bsky.social
Hidden among our immune system's seeds, scientists found special ones that could revolutionize cancer treatments and vaccines.

@deekshadeep @danapeer.bsky.social @jexpmed.bsky.social

t.co/k5lwZHxzxi
#ImmunoSky 🧪
immunosketch.bsky.social
And for the grand finale: Precursor central memory versus effector cell fate and naïve CD4+ T cell heterogeneity. A perfect reminder of immunology’s complexity—how one decision can shape an entire fate.
immunosketch.bsky.social
Imagine tiny engineers in your skin fine-tuning your nerves to detect allergens more easily.

@theILCguy @sokol_mdphd @forum-gd.bsky.social @nature.com

t.co/FjDjJ7U8Db
#ImmunoSky 🧪
immunosketch.bsky.social
Day -2 highlights an immune-sensory dialogue: A γδ T cell–IL-3 axis controls allergic responses through sensory neurons. Immunology doesn’t just fight disease—it listens, connects, and responds. A beautiful symphony of cells to close out the year.
immunosketch.bsky.social
Imagine your immune system as a symphony, where testosterone conducts uniquely tuned performances.

@petterbrodin.bsky.social @karolinskainst.bsky.social @nature.com

t.co/PP6pbUIuph
#ImmunoSky 🧪
immunosketch.bsky.social
On day -3, we spotlight adaptation: Immune system adaptation during gender-affirming testosterone treatment. A testament to the immune system’s flexibility and resilience—much like the spirit we carry into the new year.
immunosketch.bsky.social
Even at the very start, some cells in the embryo already have different jobs.

@LIwamotoStohl @zernickagoetz.bsky.social @slavovlab.bsky.social

t.co/BYpgqsn6G0
#ImmunoSky 🧪
immunosketch.bsky.social
Day -4 turns our focus to early development: Proteome asymmetry in mouse and human embryos before fate specification. A fascinating reminder that immune-related pathways often begin shaping outcomes before fate is even sealed.
immunosketch.bsky.social
Imagine the uterine lining as a garden, where special cells act as dedicated gardeners, keeping it healthy and vibrant.

@vikilovesfacs.bsky.social

t.co/CMnUKp26hw
#ImmunoSky 🧪
immunosketch.bsky.social
On day -5, we celebrate immune cells in regeneration: Dynamic roles of ILC3 in endometrial repair and regeneration. Just like the new year brings fresh beginnings, ILC3s show us how the immune system fosters repair and renewal.
immunosketch.bsky.social
Septins act like tiny security guards in our cells, triggering a self-destruct mode to fight off harmful bacteria.

@MostowyLab @DBrokatzky
@lshtm.bsky.social @cp-cellchembiol.bsky.social

t.co/0bmT2fA51l
#ImmunoSky 🧪
immunosketch.bsky.social
Day -6 dives into the mechanics of cell death: Septins promote macrophage pyroptosis. Who knew cell death pathways could bring such dramatic energy to the immunology stage?
immunosketch.bsky.social
Breast cancer cells can be kept in check in the lungs by immune cell guardians that send a "sleep signal".

@eriDalla @micpapanicolaou.bsky.social
@JAguirreGhiso @casanova-acebes.bsky.social @miriammerad.bsky.social @dentenberg.bsky.social

t.co/9GAh70ozST
#ImmunoSky 🧪
immunosketch.bsky.social
Day -7 brings us a lesson in perfect timing: Lung-resident alveolar macrophages regulate the timing of breast cancer metastasis. A reminder that, like the holiday season, the immune system knows when to act—and when to wait.
immunosketch.bsky.social
Bacteria outsmart phages with a clever card trick, going dormant to dodge attacks.

@drdorsalomon.bsky.social
@naturemicrobiol.bsky.social

t.co/S5qOcoCFOj
#ImmunoSky 🧪
immunosketch.bsky.social
Day -8 shines a light on nature’s microscopic defense systems: Gamma-Mobile-Trio systems are mobile elements rich in bacterial defensive and offensive tools. Like an immune system stocking stuffer, these mobile elements carry all the surprises—tools for attack and defense.
immunosketch.bsky.social
On day -9 of our year-end countdown, we celebrate immune engineering at its finest: A tetraspecific engager armed with a non-alpha IL-2 variant harnesses NK cells against B cell NHL. Natural killer cells armed and ready—it’s immunology’s version of Santa’s sleigh delivering precision medicine.
immunosketch.bsky.social
Scientists have invented a new "GPS" that guides our body's own fighters to destroy blood cancer cells.

@EricVivier1 @DemariaO @MorelYannis
@immunoeditor.bsky.social

t.co/LIPpsJjeSG
#ImmunoSky 🧪
immunosketch.bsky.social
In newborns, tiny traffic cops in the liver need a GPS to find their way to the bloodstream and protect against infections.

@brunaraujodavid @Kubes_Lab
@immunoeditor.bsky.social
@sciimmunology.bsky.social

t.co/YU2WdkN4HF
#ImmunoSky 🧪
immunosketch.bsky.social
Day -10: Today’s highlight takes us to the liver: Kupffer cell reverse migration into liver sinusoids mitigates neonatal sepsis and meningitis. Proof that even immune cells can come home for the holidays—and do remarkable things when they get there.
immunosketch.bsky.social
Thank you for reading, sharing, and engaging. Immunology will march on, and so will we—toward more discoveries, more papers, and hopefully, more ways to make sense of it all. Happy holidays and here’s to a new year full of resilience, balance, and maybe a few less cytokines.
immunosketch.bsky.social
Maybe it clarified a concept, sparked curiosity, or at least made someone say, “Huh, that’s actually pretty cool.” Because it is.

To wrap it all up with a proper farewell, I’ll revisit 10 of the best posts over the next 10 days—one each day as we count down to the year’s end.
immunosketch.bsky.social
it’s the pursuit of answers to systems more complex than any holiday dinner debate you’ll face this season.
It’s bittersweet to close this chapter, but I’m proud to have put this work out into the world.