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Cancer Screening & Prevention Research Group

@imperial-csprg.bsky.social

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@imperialcollegeldn.bsky.social gastrointestinal cancer research group. Led by Professor Amanda Cross & Dr Gwen Murphy @imperialsandc.bsky.social. Funded by @cancerresearchuk.org & @nihr.bsky.social. https://csprg.org.uk/ https://tinyurl.com/8v6y7zms

csprg.org.uk

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Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · Jun 24

This is the first study to show an association between distal polyp characteristics & long-term proximal colon cancer risk, helping to inform who might benefit from colonoscopy, and providing evidence for future updates of post-polypectomy surveillance guidelines.

Read it here: t.co/P6P4wA8zxF

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Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · 15h

Imperial researchers include Prof Amanda Cross & Nefeli Taravira (Surgery and Cancer), Prof Elio Riboli, Prof Marc Gunter, Sherry Morris, David Muller & Rawan Maawadh (School of Public Health), Doris Chan, Ahmed Jayedi, Kostas Tsilidis, Margarita Cariolou (WCRF CUP)

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · 15h

Our @imperialcollegeldn.bsky.social colleagues were gathered this week for @who.int IARC EPIC annual meeting to share and discover the wide range of #cancerresearch studies being carried out across this important cohort.
@wcrf.org

Group photo showing Imperial College London researchers at the European Prospective Investigation into Cancer and Nutrition annual meeting in Rome - Professor Amanda Cross, Nefeli Taravira, Professor Elio Riboli, Professor Marc Gunter, Sherry Morris, David Muller, Rawan Maawadh, Doris Chan, Ahmed Jayedi, Kostas Tsilidis, Margarita Cariolou

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Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · 1d

Also at EPIC is @imperialmed.bsky.social
#PhD candidate Rawan Maawadh (supervisor Prof Amanda Cross) giving a talk on 'Proteomic Signatures of #Obesity and their Associations with #ColorectalCancer in a Case-Cohort Study in EPIC'

Cancer researcher Rawan Maawadh giving a talk with a screen behind showing her slide presentation

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · 1d

Our @imperialmed.bsky.social #PhD candidate Nefeli Taravira is at Rome today for @who.int IARC EPIC annual meeting presenting her research on 'The impact of #education, #smoking and #alcohol on oesophageal squamous cell #carcinoma risk in the EPIC cohort'

Cancer researcher Nefeli Taravira standing beside her research poster

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · 15d

Congrats to @imperialsandc.bsky.social postdoc Dr Rhea Harewood on receiving the @cancerresearchuk.org Bridge to Academic Leadership Award! This award will support Rhea in building skills to pursue independent research & transition to group leadership in the field of proximal bowel cancer aetiology

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · Jul 3

Thrilled to share that Fangqing Li has been awarded a China Scholarship Council @imperialcollegeldn.bsky.social Scholarship!

She'll rejoin CSPRG in July as a fully funded PhD student, focusing on early-onset colorectal cancer.

Welcome back Fangqing!

#PhD #CancerResearch @imperialsandc.bsky.social

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · Jul 1

@imperialbrc.bsky.social-funded Dr Rhea Harewood & Kelly Gleason led a great #BowelCancerAwareness online session, supported by @imperialsandc.bsky.social, with Harrow THCOGIC Church members last week!

They covered bowel cancer causes, public involvement in research, & Rhea's future research plans

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · Jun 30

A huge thank you to the 3 brilliant speakers (& their supportive colleagues) from @imperialnhs.bsky.social, @imperialsandc.bsky.social who joined Dr Harewood for a PPI session with 58 EKTA Harrow community members

Valuable discussions had on breast & prostate cancer awareness & current research!

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · Jun 27

More @cancerresearchuk.org #PrevConf25 final day action
✅Heavyweight academics slug it out over GLP1 agonists importance (or not) for #cancerprevention
✅Prof Karen Brown weighs in on drugs for precision cancer prevention

www.cancerresearchuk.org/funding-for-...

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · Jun 27

Busy week catching up with all the latest in #cancerprevention at @cancerresearchuk.org #PrevConf25
✅Pressing agenda
✅Brilliant talks
✅Thought-provoking debates
✅Opportune catch-up with colleagues & collaborators

www.cancerresearchuk.org/funding-for-...

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Reposted by Cancer Screening & Prevention Research Group

Ines Perpetuo, PhD @ines-perpetuo.bsky.social · Jun 26

Come see our researchers present their research next week and check out our Keynote as well!!!

@imperialmed.bsky.social @imperial-csprg.bsky.social @imperial-edu.bsky.social @imperialcollegeldn.bsky.social

Imperial Early Career Researcher Institute @imperialecri.bsky.social · Jun 24

Join us on Wednesday 2 July for the Early Career Researcher Showcase! 🎉

Meet our fantastic research community, hear about their research & cast your People's Choice vote! 🗳️

➡️View the entries: tinyurl.com/ecrshw
🎟️Book your ticket: tinyurl.com/ecrtic

#ECRShowcase

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Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · Jun 24

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Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · Jun 24

New analyses of #UKFSST data identify distal polyp characteristics associated with future proximal colon cancer risk.

Funders: @cancerresearchuk.org @nihr.bsky.social

Authors: R Harewood, K Wooldrage, E Robbins, J Kinross, C Wagner & AJ Cross

Journal: @bmj.com Open Gastroenterology

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · Jun 24

New paper alert!

Larger or high-grade dysplastic distal adenomas found on flexi-sig screening are associated with ⬆️ risk of future proximal colon cancer.

No associations for number or histology of distal adenomas or any distal hyperplastic polyp characteristics

@bmj.com OpenGastro
t.co/P6P4wA8zxF

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · May 29

We took a break from the office to celebrate the successful PhD vivas of both Emma and Sharon with a sunny picnic! It was great to have the opportunity to mark this achievement as a group, congratulations to you both!
#PhDone

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · May 22

Thanks @qubelfastofficial.bsky.social @helencolemanqub.bsky.social for inviting Amanda J Cross to give the Charlotte Jackson Gift Lecture today! A great opportunity to share our @cancerresearchuk.org funded work on #BowelCancer early detection & how our findings are influencing policy & patient care

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · May 12

4 years ago... #timeflies

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · May 12

A huge congratulations to our brilliant @imperialsandc.bsky.social
@cancerresearchuk.org #PhD - Dr Emma Robbins! - on successfully passing her #viva today!

An incredible achievement and well-deserved recognition of her hard work and dedication. We are so proud to celebrate with her!

😀👏🥳

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Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · Apr 24

Post doc Dr Rhea Harewood sharing #BowelCancerAwareness at a community outreach event with the Harrow THCOGIC church.

The group discussed how #BowelCancer is caused, how we can screen to find it earlier and how to improve public involvement in bowel cancer research

#EDI #CancerResearch

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Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · Apr 23

Improving involvement of EDI groups in #BowelCancer research is essential to make medical research more equitable

Rhea Harewood & Kelly Gleason collaborated with the Asian Women Cancer Group to hear their opinions on Rhea's future bowel #CancerResearch plans!

#BowelCancerAwareness

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · Apr 23

It's #BowelCancerAwareness Month

Spotlight on our @nihr.bsky.social post-doc Dr Rhea Harewood's work to improve involvement & participation of minority ethnic groups in #BowelCancer research

This work is funded by the @imperialsandc.bsky.social and @imperialcollegeldn.bsky.social EDI seed funds!

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · Apr 7

8/8
Impact

Effective allocation of surveillance colonoscopies is crucial to protect higher-risk pts from CRC while minimising invasive procedures for low-risk pts.

Our unique data will inform recommendations for ongoing surveillance in future post-polypectomy surveillance guidelines.

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · Apr 7

7/8
Conclusion

Pts with high-risk findings at both baseline & SC1 needed a second surveillance colonoscopy, whereas those with low-risk findings at SC1 did not, regardless of their baseline findings.

We couldn't draw conclusions for the LR-HR group due to limited CRC cases.

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · Apr 7

6/8
Findings:

Compared to the general population, CRC incidence after SC1 was:
▪️ ~0.5 times lower in the LR-LR group
▪️ - Non-significantly different in the HR-LR or LR-HR groups, although the 95%CI for the LR-HR group was wide due to few CRC cases
▪️ - ~3 times higher in the HR-HR group

Cancer Screening & Prevention Research Group @imperial-csprg.bsky.social · Apr 7

5/8
Methods

We examined CRC incidence after SC1. Median follow-up was 8 years. CRC incidence in each group was then compared with that in the general population.