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Immunotherapy Advances @imtadvances.bsky.social · 9d

🧬 Low MHC-I expression can help tumours evade the immune system.

Discover strategies to boost MHC-I and improve immunotherapy in paediatric and adult cancers. 🔬

Read: https://bit.ly/45vtfmp

#Immunotherapy #CancerResearch #MHCI

graphical abstract for Strategies to overcome low MHC-I expression in paediatric and adult tumours

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Immunotherapy Advances @imtadvances.bsky.social · 12d

💡 Tumour-reactive plasma cells are emerging as powerful players in cancer immunotherapy!

Explore their role in antibody-based, personalized treatments. 🔬

Read: https://bit.ly/3SVZsMC

#Immunotherapy #CancerResearch #PlasmaCells

graphical abstract for Tumour-reactive plasma cells in antitumour immunity: current insights and future prospects

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Immunotherapy Advances @imtadvances.bsky.social · 13d

💥Open Access review: NK cells as cancer fighters!

From CAR-NK cells to checkpoint inhibitors, explore cutting-edge strategies to harness NK-cell immunity. 🔬

Read: https://bit.ly/4j8dKEW

#Immunotherapy #NKcells #CancerResearch

graphical abstract of Harnessing natural killer cell effector function against cancer

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Immunotherapy Advances @imtadvances.bsky.social · 15d

Could CD200R blockade enhance PD-1 therapy?

A humanised mouse study found limited benefit in colorectal & lung cancer, but points to potential in CD200⁺ tumours.

🔗 https://bit.ly/4pdAtDw

#Immunotherapy #CancerResearch

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Immunotherapy Advances @imtadvances.bsky.social · 19d

Exploring the role of DC3s in solid tumours! These dendritic cells can boost anti-tumour immunity or contribute to immunosuppression depending on the TME.

Discover their potential for targeted therapies 👉 https://bit.ly/3T2blRg

#EMDS2025 #Immunotherapy #CancerResearch

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Immunotherapy Advances @imtadvances.bsky.social · 21d

TAMs drive tumour progression, metastasis & therapy resistance.

Targeting their surface receptors may unlock new cancer immunotherapy strategies, insights for #EMDS2025

🔗 https://bit.ly/4i95qnm

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Immunotherapy Advances @imtadvances.bsky.social · 22d

Could JAK inhibitors be a treatment for STAT3 gain-of-function?

Study shows symptom improvement in patients with this rare immune disorder.

Read here🔗 https://bit.ly/4p7Vxer

#Immunotherapy

Immunotherapy Advances @imtadvances.bsky.social · 22d

⏳ Last chance! Submit your research on immunotherapies for inborn errors of immunity to our Special Collection before the end of September.

Submit here: https://bit.ly/4p96dJA
##Immunology

Immunotherapy Advances @imtadvances.bsky.social · 26d

It's the final day of Cancer Immunology: Advances & Therapeutic Application, don’t miss our journals manager Laura Franklin giving a talk at 11:00 AM today!

Learn more about publishing opportunities and journal initiatives.
##CancerImmunology #Immunotherapy

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Immunotherapy Advances @imtadvances.bsky.social · 27d

Are you attending Cancer Immunology: Advances & Therapeutic Application and working on cancer vaccines?
Share your latest research in our Special Collection on global advances, personalised or off-the-shelf vaccines, clinical trials & more.

Submit here: https://bit.ly/4mPbW64

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Immunotherapy Advances @imtadvances.bsky.social · 28d

Attending Cancer Immunology: Advances & Therapeutic Application?

Come and visit us at our booth to learn more about our journals, upcoming special collections, and opportunities to publish! #CancerImmunology #Immunology

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Immunotherapy Advances @imtadvances.bsky.social · Sep 8

NLRP3 inflammasome activation in sensory neurons drives chronic inflammatory & osteoarthritis pain.

Blocking this pathway may offer a route to new treatments.

Read more🔗 https://bit.ly/3UX7Tbz

#ChronicPain #Immunology

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Immunotherapy Advances @imtadvances.bsky.social · Sep 6

Working on targeted therapies for inborn errors of immunity?

Our Special Collection on genetics-guided immunotherapy closes at the end of this month, submit your research today!

Learn more: https://bit.ly/4p96dJA

Immunotherapy Advances @imtadvances.bsky.social · Sep 5

🚀 Going viral against #Glioblastoma!

Discover how oncolytic viruses are reshaping the immune landscape of GBM, boosting therapy response & offering new hope.

Open Access 👉 https://bit.ly/3UMBhkw #Immunotherapy #CancerResearch

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Immunotherapy Advances @imtadvances.bsky.social · Sep 3

High-affinity TCR bispecific (ImmTAC®) redirects T cells to efficiently kill PRAME+ tumor cells across multiple cancers. Combination with PD-1 blockade may enhance activity.

By Ribeiro et al.

🔗 https://bit.ly/40o5kT8
##Immunotherapy #CancerResearch #PRAME

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Immunotherapy Advances @imtadvances.bsky.social · Aug 29

💉 During #ImmunisationAwarenessMonth, a timely reminder: mRNA COVID-19 vaccines (Pfizer & Moderna) remain highly effective at preventing hospitalisation (84–86%), even with variant challenges.

🔗 https://bit.ly/43rUWvP
##Vaccineswork #immunology

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Immunotherapy Advances @imtadvances.bsky.social · Aug 28

💉 Cancer vaccines are regaining momentum with advances in neoantigen science, tumour mutational burden & mRNA technology.

A deeper understanding of dendritic cells and immune mechanisms is key to unlocking their full potential. 🚀
##ImmunisationAwarenessMonth

🔗 https://bit.ly/4cefxGm

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Immunotherapy Advances @imtadvances.bsky.social · Aug 22

Why are paediatric tumours less responsive to immunotherapy?

One reason: MHC-I downregulation. Restoring it could make tumour cells visible again to CD8 T cells.

🔗 https://bit.ly/45vtfmp

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Immunotherapy Advances @imtadvances.bsky.social · Aug 20

Smallpox vaccines provide important cross-protection against Mpox. Evidence from past outbreaks informed the use of the MVA–BN vaccine during 2022, highlighting how immunisation strengthens preparedness for emerging threats.
##NationalImmunisationAwarenessMonth

👉 https://bit.ly/4jSbodz

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Immunotherapy Advances @imtadvances.bsky.social · Aug 19

Bispecific T-cell engagers (BiTEs) redirect T-cells to attack tumors, but their power is often limited by immune checkpoints & suppressive microenvironments.

💡 Combination strategies with checkpoint inhibitors, chemo, or oncolytic viruses could boost effectiveness.

👉 https://bit.ly/4oKabbt

Combination therapies for the optimisation of Bispecific T-cell Engagers in cancer treatment graphical abstract

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Immunotherapy Advances @imtadvances.bsky.social · Aug 17

🌟 Researchers in cancer immunology: showcase your work in our Special Collection: Cancer Vaccines Global Advances!

Submit studies, reviews, or clinical updates on personalized & off-the-shelf vaccines.

Deadline: Dec 2025.
##CancerResearch #Immunotherapy

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Immunotherapy Advances @imtadvances.bsky.social · Aug 16

Did you know? 🩺 Patients on immune checkpoint inhibitors can develop inverse psoriasis, often mistaken for fungal infections.

Early recognition by oncologists & dermatologists is key to better care. 🧴🩹
##NationalPsoriasisMonth #Psoriasis

🔗 https://bit.ly/4lw91iq

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Immunotherapy Advances @imtadvances.bsky.social · Aug 15

Liu et al. show that SMAC mimetics + IFNγ can reprogram human macrophages to phagocytose live pancreatic & breast cancer cells, revealing a TNFα-driven feedback loop that sustains this activity.

Read now🔗 https://bit.ly/4mBGMix

#Immunotherapy #CancerResearch

Immunotherapy Advances @imtadvances.bsky.social · Aug 8

📅 August is #NationalPsoriasisMonth 🧬

Study finds similar immune responses in chronic plaque psoriasis patients on Humira® whether they stayed on it or switched with AVT02, supporting interchangeability.

🔗 https://bit.ly/3J8pESs

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Immunotherapy Advances @imtadvances.bsky.social · Aug 7

Tumour-reactive plasma cells (TRPCs) are emerging as potent players in cancer immunotherapy 🧬🧪

Chen et al explore their potential, challenges in neoantigen targeting, and prospects for personalised therapy.

📖 https://bit.ly/3SVZsMC

#Immunotherapy #CancerResearch

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