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International Society of Genetic Genealogy @isogg.bsky.social · 9d

Registration ends 30 Sept 2025 for the virtual East Coast Genetic Genealogy Conference. You have until 31 Dec 2025 to watch all of the recordings. There’s an ISOGG presentation where we celebrated ISOGG’s 20th year, review the history and discuss future goals. #ISOGG #DNA #ECGGC ecggc.org

2025 East Coast Genetic Genealogy Conference - ECGGC

East Coast Genetic Genealogy Conference

ecggc.org

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International Society of Genetic Genealogy @isogg.bsky.social · 10d

“Another mutation of a protein in the virus’s membrane improved its ability to bind to entry point receptors in human cells, making it more resilient and infectious.” #isogg #DNA #epigentics #1918Flu #SpanishFlu
www.the-independent.com/news/science...

Century-old lungs stored in jar reveal how 1918 Spanish flu pandemic began

Findings could lead to better understanding of how viruses adapt to humans during a pandemic

www.the-independent.com

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International Society of Genetic Genealogy @isogg.bsky.social · 14d

“Riding a bike is associated with a 19% lower risk of all-cause dementia and a 22% lower risk of Alzheimer’s disease, compared with taking nonactive travel modes such as a car, bus or train…” #ISOGG #DNA #epigenetics www.cnn.com/2025/09/20/h...

Cycling linked with lower dementia risk, study finds | CNN

Cycling instead of driving has been linked with a lower risk of dementia and Alzheimer’s disease, a large study has found.

www.cnn.com

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International Society of Genetic Genealogy @isogg.bsky.social · 16d

New finding on #osteoporosis: “Researchers from the University of Leipzig in Germany and Shandong University in China, identified the cell receptor GPR133 (also known as ADGRD1) as being crucial to bone density, via bone-building cells called osteoblasts.” www.sciencealert.com/new-breakthr...

New Breakthrough to Strengthen Bones Could Reverse Osteoporosis

A new study points to a key bone-strengthening mechanism at work in the body, which could be targeted to treat the bone-weakening disease, osteoporosis.

www.sciencealert.com

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International Society of Genetic Genealogy @isogg.bsky.social · 21d

Nice blog post by Linda Yip on the East Coast Genetic Genealogy Conference which you can STILL sign up to watch the recordings through Dec 31, 2025. Registration ends Sept 30,2025 so don’t procrastinate on registering. #geneticgenealogy #ISOGG #DNA #ECGGC
past-presence.com/2025/09/14/k...

East Coast Genetic Genealogy Conference 2025: My Experience

Explore my review of the East Coast Genetic Genealogy Conference 2025, featuring insights, sessions, and a virtual learning experience.

past-presence.com

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International Society of Genetic Genealogy @isogg.bsky.social · 24d

“The authors identified a class of lithium compounds that can evade capture by amyloid beta. Treating mice with the most potent amyloid-evading compound, called lithium orotate, reversed Alzheimer’s disease pathology, prevented brain cell damage, and restored memory.”
hms.harvard.edu/news/could-l...

Could Lithium Explain — and Treat — Alzheimer’s Disease?

Study: Lithium loss ignites Alzheimer’s, but lithium compound can reverse disease in mice

hms.harvard.edu

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International Society of Genetic Genealogy @isogg.bsky.social · 29d

"Moreover, G2a2* is represented by only one sub-lineage (G2a2b2a1a1b*, L497) except for the Iceman, which carries a different one (G2a2a1a2a1a1b, G-Z6208, or formerly G2a2a1a2 L-91"
#DNA #ISOGG #YHaplogroupG #AncientDNA #Iceman

www.nature.com/articles/s41...

Genomic diversity and structure of prehistoric alpine individuals from the Tyrolean Iceman’s territory - Nature Communications

Here, the authors perform genomic analysis of prehistoric individuals from the Italian Alps, to reveal a genetic shift from the Mesolithic to the Neolithic and genetic continuity from the Neolithic to...

www.nature.com

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International Society of Genetic Genealogy @isogg.bsky.social · Sep 9

Ireland’s Genealogical Gazette FREE talk on 9 Sept 2025 at 20:00 “Isotopes and Ancestry: Exploring how Archaeochemistry can answer Genealogical Questions,” given by Dr Ashley McCall, an independent researcher based in Dublin. Join via Zoom ID 844 6097 4398 and passcode 66 18 37
#DNA #ISOGG #Ireland

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International Society of Genetic Genealogy @isogg.bsky.social · Sep 6

“Scientists just found a sugar switch that protects your brain from Alzheimer's. In addition to a new approach in Alzheimer’s research, study from Buck Institute could explain why GLP-1 drugs show promise against dementia.” #isogg #DNA #epigenetics #glp1
www.sciencedaily.com/releases/202...

Scientists just found a sugar switch that protects your brain from Alzheimer's

Scientists have uncovered a surprising sugar-related mechanism inside brain cells that could transform how we fight Alzheimer’s and other dementias. It turns out neurons don’t just store sugar for fue...

www.sciencedaily.com

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International Society of Genetic Genealogy @isogg.bsky.social · Sep 5

“Moreover, we demonstrated that a higher FI score of mtDNA variants was associated with both premature epigenetic aging in the early 20s and premature biological aging in the late 20s." #isogg #DNA #epigenetics #haplogroups
www.nature.com/articles/s41...

Mitochondrial DNA variants and their impact on epigenetic and biological aging in young adulthood - Translational Psychiatry

Translational Psychiatry - Mitochondrial DNA variants and their impact on epigenetic and biological aging in young adulthood

www.nature.com

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International Society of Genetic Genealogy @isogg.bsky.social · Aug 31

“Results from a randomized controlled trial reveal that vitamin D supplementation helps maintain telomeres, protective caps at the ends of chromosomes that shorten during aging and are linked to the development of certain diseases.” #isogg #telomeres #epigenetics news.harvard.edu/gazette/stor...

Vitamin D supplements may slow biological aging — Harvard Gazette

Trial shows protection against telomere shortening, which heightens disease risk.

news.harvard.edu

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International Society of Genetic Genealogy @isogg.bsky.social · Aug 12

Well done study on the HAY surname! #ISOGG #DNA #FTDNA #FamilyTreeDNA #BigY #Ychromosome #Hay #geneticgenealogy
www.biorxiv.org/content/10.1...

What can Y-DNA analysis reveal about the surname Hay?

The family name Hay (plus associated spelling variants) is a prominent Anglo-Norman-in-origin surname that has been well-documented as a Scottish noble lineage since the 12th century CE. Their histori...

www.biorxiv.org

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International Society of Genetic Genealogy @isogg.bsky.social · Aug 5

“…scientists made a surprising discovery: caffeine doesn’t act on this growth switch directly. Instead, it works by activating another important system called AMPK, a cellular fuel gauge that is evolutionarily conserved in yeast and humans.” #DNA #epigenetics #coffee

www.qmul.ac.uk/media/news/2...

Caffeine could slow cellular ageing, new research shows how

www.qmul.ac.uk

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International Society of Genetic Genealogy @isogg.bsky.social · Aug 1

Have you had the Shingles vaccine? If you’ve had the Shingles vaccine (and/or RSV vax) then you may have given yourself a dementia preventative. #isogg #dna #shingles #shingrix #RSV #epigenetics www.sciencealert.com/huge-study-r...

Huge Study Reveals 2 Vaccines That Appear to Reduce Dementia Risk

Some immunizations may be quietly protecting us from cognitive decline.

www.sciencealert.com

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International Society of Genetic Genealogy @isogg.bsky.social · Jul 31

“Intranasal insulin has been clinically tested in Alzheimer’s Disease patients, demonstrating positive effects on memory and a decrease in Aβ42 levels.” #DNA #epigenetics #isogg #Alzheimers #insulin

pmc.ncbi.nlm.nih.gov/articles/PMC...

Insulin-inspired peptides may open new pathways to treat Alzheimer’s disease

pmc.ncbi.nlm.nih.gov

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International Society of Genetic Genealogy @isogg.bsky.social · Jul 29

“Over an average follow-up of 6.7 years, 280 participants, or 27.3 percent, were diagnosed with Alzheimer’s. Researchers found that 39 percent of the “total effect of egg intake” was linked to choline, a nutrient in egg yolks known to support memory & brain function.”
thehill.com/policy/healt...

thehill.com

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International Society of Genetic Genealogy @isogg.bsky.social · Jul 11

“When IDO1 is blocked, however, macrophages regain their ability to absorb cholesterol.This suggests that reducing IDO1 activity could offer a new way to help prevent heart disease by keeping cholesterol levels in check.” #DNA #isogg #epigenetics #cholesterol

www.news-medical.net/news/2025062...

New enzyme can be "turned off" to restore cholesterol balance and reduce inflammation

Scientists at The University of Texas at Arlington have identified a new enzyme that can be "turned off" to help the body maintain healthy cholesterol levels-a significant development that could lead ...

www.news-medical.net

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International Society of Genetic Genealogy @isogg.bsky.social · Jul 9

“These findings identify a light-responsive cell-intrinsic timer that controls time-of-day variations in antibacterial activity.” #isogg #DNA #epigenetics #circadian

www.science.org/doi/10.1126/...

A light-regulated circadian timer optimizes neutrophil bactericidal activity to boost daytime immunity

The neutrophil clockwork boosts daytime immunity against bacterial infection.

www.science.org

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International Society of Genetic Genealogy @isogg.bsky.social · Jul 7

Does Alzheimer’s even come close to being an

Does Alzheimer’s even come close to being an Autoimmune Disease? #DNA #epigenetic #isogg
www.j-alz.com/editors-blog...

Does Alzheimer’s even come close to being an Autoimmune Disease? | Journal of Alzheimer's Disease

www.j-alz.com

International Society of Genetic Genealogy @isogg.bsky.social · Jul 6

“Addressing sleep disturbance and deficiency may have a positive impact on risk for incident dementia and all-cause mortality among older adults.”
#isogg #epigenetics #dementia #alzheimers

pubmed.ncbi.nlm.nih.gov/33570509/

Examining sleep deficiency and disturbance and their risk for incident dementia and all-cause mortality in older adults across 5 years in the United States - PubMed

Addressing sleep disturbance and deficiency may have a positive impact on risk for incident dementia and all-cause mortality among older adults.

pubmed.ncbi.nlm.nih.gov

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International Society of Genetic Genealogy @isogg.bsky.social · Jul 4

“Their study, published in the journal Nature, describes the first whole ancient Egyptian genome, and the oldest DNA sample from Egypt to date.” #DNA #isogg #Egypt #Nature

amp.dw.com/en/dna-shows...

DNA shows ancient Egyptians had surprising foreign roots – DW – 07/02/2025

Scientists have sequenced the oldest known DNA from ancient Egypt. It belonged to a potter who lived 4,500 years ago. This rare genetic snapshot offers new insights into the diverse ancestry of early ...

amp.dw.com

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International Society of Genetic Genealogy @isogg.bsky.social · Jun 29

“This innovative strategy could potentially revolutionize our ability to address genetic hearing impairments, offering hope for more effective and durable treatments for individuals across a wider age range and at various stages of hearing loss progression.” #DNA
www.frontiersin.org/journals/neu...

Frontiers | Gene therapy for hearing loss: challenges and the promise of cellular plasticity and epigenetic modulation

Hearing loss can profoundly impact an individual’s quality of life, affecting communication, social interactions, and overall well-being. Many people with he...

www.frontiersin.org

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International Society of Genetic Genealogy @isogg.bsky.social · Jun 25

“Using population genetics, kinship analyses and the study of networks of identity-by-descent haplotype segment sharing, we elucidate the social and genetic dynamics of these communities between 4800−3900 calibrated years BCE.” #isogg #ancientdna #DNA #CarpathianBasin
www.nature.com/articles/s41...

Ancient DNA reveals diverse community organizations in the 5th millennium BCE Carpathian Basin - Nature Communications

A genomic study of 125 individuals from the Carpathian Basin (4800–3900 BCE) reveals different kinship systems in nearby Copper Age communities, and highlights both genetic continuity and contrasting ...

www.nature.com

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International Society of Genetic Genealogy @isogg.bsky.social · Jun 24

New to epigenetics? University College London has produced Epigenetics for the Lay Person. #DNA #isogg #epigenetics

www.ucl.ac.uk/population-h...

Epigenetics – Lay Version

www.ucl.ac.uk

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International Society of Genetic Genealogy @isogg.bsky.social · Jun 19

“Mitochondrial DNA extracted from these cemeteries showed that although the female line was linked to Early Neolithic farming communities, the male line was similar to that of Jutlandic populations.” #isogg #ancientdna #DNA #Scotland
archaeologymag.com/2025/06/pola...

DNA reveals Poland’s first kings may have Scottish origins, challenging founding myths

DNA analysis suggests Poland’s Piast dynasty may trace its origins to ancient Scottish Picts, reshaping early Polish royal history.

archaeologymag.com

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