Jakson Luk
@jaksonluk.bsky.social
“Those who cannot remember the past are condemned to repeat it”
- George Santayana
Infection Microbiologist/Bioengineer 🧬🦠🧫🔧🔬. Eurasian-Hongkonger. Born in British Hong Kong 🇬🇧🐲🦁. Stand for Freedom, Democracy and Human Rights.
- George Santayana
Infection Microbiologist/Bioengineer 🧬🦠🧫🔧🔬. Eurasian-Hongkonger. Born in British Hong Kong 🇬🇧🐲🦁. Stand for Freedom, Democracy and Human Rights.
Read more:
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Autologous human iPSC–derived alveolus-on-chip reveals early pathological events of Mycobacterium tuberculosis infection
An autologous, genetically tractable human iPSC–derived alveolar model is developed to study tuberculosis.
www.science.org
January 3, 2026 at 4:14 AM
Read more:
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
🔬Modeling early Host-Pathogen interactions between human and Mycobacterium tuberculosis.
🧫Study the functions of genes in a cell type-specific manner.
🌬️Study host responses against different foreign air-borne particles.
💊Drug toxicity testing and development
Personalised medicine.
🧫Study the functions of genes in a cell type-specific manner.
🌬️Study host responses against different foreign air-borne particles.
💊Drug toxicity testing and development
Personalised medicine.
January 2, 2026 at 10:03 PM
🔬Modeling early Host-Pathogen interactions between human and Mycobacterium tuberculosis.
🧫Study the functions of genes in a cell type-specific manner.
🌬️Study host responses against different foreign air-borne particles.
💊Drug toxicity testing and development
Personalised medicine.
🧫Study the functions of genes in a cell type-specific manner.
🌬️Study host responses against different foreign air-borne particles.
💊Drug toxicity testing and development
Personalised medicine.
We are able to:
🫁Recreate alveolar epithelial and endothelial barriers on chip.
⚖️Achieve a balance of alveolar cell types.
🧫Show the complex multicellular composition changes cell status.
🧬Build lung-on-chip with genetic manipulation in specific cell type.
☠️Recapitulate early Tuberculosis hallmarks.
🫁Recreate alveolar epithelial and endothelial barriers on chip.
⚖️Achieve a balance of alveolar cell types.
🧫Show the complex multicellular composition changes cell status.
🧬Build lung-on-chip with genetic manipulation in specific cell type.
☠️Recapitulate early Tuberculosis hallmarks.
January 2, 2026 at 10:03 PM
We are able to:
🫁Recreate alveolar epithelial and endothelial barriers on chip.
⚖️Achieve a balance of alveolar cell types.
🧫Show the complex multicellular composition changes cell status.
🧬Build lung-on-chip with genetic manipulation in specific cell type.
☠️Recapitulate early Tuberculosis hallmarks.
🫁Recreate alveolar epithelial and endothelial barriers on chip.
⚖️Achieve a balance of alveolar cell types.
🧫Show the complex multicellular composition changes cell status.
🧬Build lung-on-chip with genetic manipulation in specific cell type.
☠️Recapitulate early Tuberculosis hallmarks.
An amazing team of interdisciplinary scientists The Francis Crick Institute and AlveoliX is behind this piece of work generously supported by @wellcomeleap.bsky.social HOPE - Human Organs, Physiology, and Engineering Program.
January 2, 2026 at 10:03 PM
An amazing team of interdisciplinary scientists The Francis Crick Institute and AlveoliX is behind this piece of work generously supported by @wellcomeleap.bsky.social HOPE - Human Organs, Physiology, and Engineering Program.