JAMA Network Open
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JAMA Network Open is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications. 🌐 JAMANetworkOpen.com
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Use of sugammadex during minimally invasive inguinal hernia repair was associated with a lower rate of postoperative urinary retention and shorter hospital stay compared to traditional reversal agents. ja.ma/4nN4sB6
JAMA Network Open article: "Sugammadex for Postoperative Urinary Retention in Minimally Invasive Inguinal Hernia Repair: A Nonrandomized Clinical Trial" by William R. Lorenz, Alexis M. Holland, Brittany S. Mead, et al. Published Oct 7, 2025.
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Black adolescents, on average, reported experiencing 6 online race-related experiences per day and negative experiences were associated with poor #mentalhealth. ja.ma/42sLS8E
https://ja.ma/48SF0VZ
Adolescents’ Race-Related Online Experiences and Mental Health
ja.ma
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A two-stage screening of 754 preschoolers in Austria found 4.4% needing therapy for motor deficits and 2.1% with critical motor skills based on validated assessments, yet none of these children’s parents reported concerns. ja.ma/4o7E1FS
JAMA Network Open article: "Unrecognized Motor Difficulties and Developmental Coordination Disorder in Preschool Children" by Barbara Scheiber, Claudia Spiegl, Jasmin Plattner, et al. Published October 7, 2025.
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A consensus identified six core competencies for #MedicalCannabis education in medical schools, covering pharmacology, legal issues, clinical evidence, risks, and management to address knowledge gaps and support informed patient care. ja.ma/3KCfU3G
JAMA Network Open article: "Developing Medical Cannabis Competencies: A Consensus Statement." By Yuval Zolotov, Leslie Mendoza Temple, Richard Isralowitz, et al. Published Oct 7, 2025.
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Most nonprotected class drugs with #FDA accelerated approval were covered by some #Medicare Part D plans, but fewer than half were widely available, and most coverage appeals were denied. ja.ma/42s1k4Q
Line graph shows the proportion of Medicare Part D plans over a decade. Several drugs are tracked including Deferiprone, Droxidopa, and Seladelpar. Droxidopa and Bedaquiline show a high proportion, while Seladelpar's proportion remains low.
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Among primary care patients sending portal messages, physician response rates within 1 business day were lower for Black, Hispanic, dual-eligible, and Spanish-preferring patients compared to White, commercially insured, and English-preferring patients. ja.ma/46UaOY1
Three bar graphs show care team member response percentages, comparing race & ethnicity, insurance type, & primary language to response time in business days (1 vs. 3). Each graph displays varying response rates across categories.
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TEM-AID, an #AI system for analyzing kidney TEM images, accurately segmented glomerular structures and outperformed pathologists in diagnosing glomerular disease subtypes. ja.ma/4mQIJXy
The image contains 5 plots: Prevalence of subtype by center, classification performance of TEM-AID system, confusion matrix of training/validation set, and precision in the Huayin validation set.
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Among children across the US enrolled in #Medicaid or CHIP, 2.8% of acute care encounters occurred out of state overall, but this rate increased to 10% for those living within one mile of a state border. ja.ma/4h1LCDy
Graph shows out-of-state healthcare encounters decrease with distance to state border. Lines represent 'Both', 'Any hospital', 'Children's hospital', 'Neither'. Encounters drop from 40% to 10% for 'Both' as distance increases.
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Among older adults visiting ambulatory clinics, nearly half identified social activities and inclusiveness as what matters most, with this trend increasing over time and consistent across demographic groups. ja.ma/3KDyto7
A line graph from 2021-2024 shows what matters to patients (%). Social trends upward from ~39% to ~55%, Health declines from ~25% to ~19%, Independence rises from ~15% to ~18%, Family declines from ~17% to ~7%, Other is stable near 2%.
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This qualitative study of locally transmitted malaria showed that outbreaks were contained within states, with Florida’s P vivax cases linked to a single strain distinct from those in Texas and Arkansas. ja.ma/4mVoTdR
Line graph showing malaria cases from 1972 to 2024. The orange line represents total cases, blue represents Plasmodium falciparum cases, and gray represents Plasmodium vivax cases. Total cases peaked around 1980 and again in 2018.
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Implementation of the SIPS surgical handover system was associated with improvements in handover quality, patient physiology, and staff perceptions of safety without prolonging handover meetings. ja.ma/46PxqsE
Line graph showing "Handovers/wk where interention was used, %" vs "Intervention week". The graph starts from 0 and rises sharply to 80% by week 2, plateaus around 100% between weeks 5-14, then fluctuates between 80% and 100% until week 20.
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Many patient-administered antiemetics in ACA and Medicaid plans are subject to coverage restrictions, and the degree of restriction varies considerably across plans, states, and medication types. ja.ma/3KAOds4
Bar graph comparing covered drug formulations (%) under different utilization management types (prior authorization, quantity limits, step therapy) and coverage types (ACA, Medicaid, etc.), split by brand vs. generic drugs.
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Restrictive diagnostic stewardship measures decreased blood culture use in pediatric care without increasing mortality, length of stay, or readmissions, and maintained stable culture positivity rates even among medically complex patients. ja.ma/3WpSCk1
Four graphs show blood culture positivity and collection rates in emergency and inpatient departments from August 2023 to January 2025, divided into pre- and stewardship measures.
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Unfavorable patterns of cardiovascular health throughout young adulthood are linked to a significantly increased risk of developing cardiovascular disease later in life. ja.ma/3J0TOr3
Two graphs display CVH scores. The first shows trajectories with age, featuring lines for persistently high, moderate, declining, and moderate-to-low declining scores. The second graph shows CVH status changes from year 0 to year 20 in a table.
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In this quality improvement study, a multifaceted deimplementation strategy to reduce unnecessary preoperative testing before common, low-risk surgical procedures was feasible to implement. ja.ma/4pOzTw2
Line graph showing preoperative testing rates for Sites 1, 2, and 3, and overall, over time. The X axis displays months (March-April, May-June, July-August), and the Y axis shows rate (0-0.8). Site 1 drops in May-June but increases in July-August.
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Patients with restless leg syndrome are at higher risk for developing #Parkinson disease, and dopamine agonist treatment is linked to later and less frequent PD diagnoses. ja.ma/3KXLSY7
Graph showing cumulative incidence rate vs. follow-up duration for 'Control', 'RLS no DA', and 'RLS and DA'. 'RLS no DA' increases more rapidly, whereas 'RLS and DA' increases slowly over the duration.
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Among Mexican-American adults living at the border, almost all individuals with #obesity by BMI had excess body fat, while a substantial number of those who were overweight with BMI below 30 also had excess adiposity that BMI alone did not identify. ja.ma/3WijBhs
JAMA Network "Excess Adiposity Without Obesity in a High-Risk Population" by Alexandra B. Palmer, Rashedeh Roshani, and Joseph B. McCormick. Published online October 3, 2025.
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Among critically ill patients with severe acute kidney injury, standard initiation of kidney replacement therapy was more cost-effective than accelerated initiation, providing better quality-adjusted life-years despite higher costs per patient. ja.ma/4o6ijCf
Flowchart of CKD progression. States: 1. No CKD, 2. CKD and not KRT dependent, 3. Alive and KRT dependent, 4. Dead. Arrows indicate possible transitions with probabilities P1,1, P1,2, P1,3, P1,4, P2,1, P2,2, P2,4, P3,1, P3,2, P3,3, P3,4.
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From 2018 to 2020, two in five eligible beneficiaries did not enroll in #Medicare Savings Programs to help pay out-of-pocket costs, with enrollment rates varying by state and being higher among Medicare Advantage members than those in Traditional Medicare. ja.ma/46YTRMe
Horizontal bar graph showing take-up rates by state, with California having the highest rate and Ohio the lowest. Error bars indicate variability. "Take-up rate, %" labels the x-axis, with state names listed vertically on the y-axis.
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Among US adults who consume alcohol, many expressed support for policies to protect children from alcohol ads and to require calorie information, standard drink information, and cancer warnings on alcohol containers. ja.ma/4nDZA0U
Horizontal bar graph showing participant support, neutrality, and opposition to alcohol-related regulations like calorie info, ad bans, and cancer warnings. Most support requiring calorie information. 'Participants, %' on x-axis.
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Among women whose #BreastCancer was detected at mammography screening, those who missed the immediate past screening round had worse tumor characteristics and poorer survival. ja.ma/46NMDdI
Two graphs compare survival rates over 20 years. Graph A shows 'Breast cancer-specific survival' and Graph B shows 'Distant metastasis-free survival'. In both, participants have a higher survival rate than nonparticipants.
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Among patients with traumatic acute subdural hematoma, those treated in centers that prefer acute surgery had outcomes similar at 6 months to those treated in centers that prefer conservative treatment. ja.ma/42lzQho
JAMA Network publication titled "Acute Surgery vs Conservative Treatment for Traumatic Acute Subdural Hematoma" by Thomas A. Van Essen et al. Published online October 3, 2025.
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This meta-analysis estimates a 28% increase in vaccine effectiveness from a second #influenza vaccine dose in the first year for children younger than 3 years, but no increase when the age range is broadened to children younger than 9 years. ja.ma/4hdvn6F
JAMA Network article titled "Comparison of 2 Doses vs 1 Dose in the First Season Children Are Vaccinated Against Influenza: A Systematic Review and Meta-Analysis." Published online October 3, 2025.
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Among 140 studies reviewed, #AI showed high performance in identifying several anogenital conditions from images, but most research focused on mpox and was limited by bias and lack of clinical validation. ja.ma/46RsSlo
JAMA Network: 'Use of AI in Identification of Sexually Transmitted Infections and Anogenital Dermatoses: A Systematic Review and Meta-Analysis' by Nyi Nyi Soe, Ingsun Isika Kusnandar, Phyu Mon Latt, et al. Published Oct 3, 2025.
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This protocol describes an RCT to assess #AI-driven clinical decision support in reducing hospital-acquired venous thromboembolism incidence in hospitalized adults across urban and rural settings in Tennessee. ja.ma/46V2Gq9
Flowchart detailing VTE-AI integration in patient care from admission to day 3. It outlines decision points on DVT prophylaxis, contraindications, and VTE-AI risk assessment, triggering alerts and best practice advisories based on risk scores. Text reads: "Admission order set", etc.