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JAMA Otolaryngology
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JAMA Otolaryngology–Head & Neck Surgery is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.

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Among patients with #HNSCC treated with radiotherapy, each additional week of treatment interruption was associated with decreased three-year locoregional control and survival, regardless of p16 status. ja.ma/48t3aED
December 4, 2025 at 4:30 PM
Use of glucagon-like peptide-1 receptor agonists (#GLP1RA) in adults with type 2 #diabetes was associated with an increased risk of new chronic cough compared with other second-line diabetes medications.

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December 3, 2025 at 3:00 PM
Model-based analysis of ECAPs in #CochlearImplant users showed stronger auditory nerve responses and plasticity in younger recipients, highlighting the value of early implantation. ja.ma/4pfDcMb
December 3, 2025 at 2:30 PM
Head and neck cancee is a collective term for cancers affecting the oral cavity, pharynx, larynx, salivary glands, and other sites in the head and neck region.

This Review discusses immunotherapy within the salvage setting for locally advanced, recurrent disease.

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December 2, 2025 at 11:00 AM
Use of glucagon-like peptide-1 receptor agonists (#GLP1RA) in adults with type 2 #diabetes was associated with an increased risk of new chronic cough compared with other second-line diabetes medications.

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November 30, 2025 at 3:00 PM
This Special Communication explores how mental training techniques found in sports psychology may be used by otolaryngologists to optimize surgical performance and surgeon well-being.

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November 30, 2025 at 12:00 PM
On December 1 at 10 AM ET, JAMA and JAMA Network Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, will co-chair a public, live-streamed webinar discussing a new @who.int guideline concerning #GLP-1 therapy and adults with #obesity.

Register for the webinar: ja.ma/4akt7sB
November 28, 2025 at 6:36 PM
Use of glucagon-like peptide-1 receptor agonists (#GLP1RA) in adults with type 2 #diabetes was associated with an increased risk of new chronic cough compared with other second-line diabetes medications.

ja.ma/3M2FsYm
November 28, 2025 at 3:00 PM
Up-front percutaneous ultrasound-guided core-needle biopsy offers a high diagnostic yield for neck lesions, effectively reducing the need for excisional biopsy, even when lymphoma is considered.

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November 28, 2025 at 12:00 PM
Among patients with oropharyngeal squamous cell #carcinoma, proton therapy for head and neck cancer was associated with a higher 3-year incidence of osteoradionecrosis compared with intensity-modulated radiation therapy.

ja.ma/4pCTH4N
November 27, 2025 at 4:00 PM
On December 1 at 10 AM ET, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, will co-chair a public, live-streamed webinar discussing a new WHO guideline concerning #GLP-1 therapy and adults with #obesity.

Register for the webinar: ja.ma/4pwD8Y7
November 26, 2025 at 5:00 PM
Use of glucagon-like peptide-1 receptor agonists (#GLP1RA) in adults with type 2 #diabetes was associated with an increased risk of new chronic cough compared with other second-line diabetes medications.

ja.ma/3XfGfHV
November 26, 2025 at 4:30 PM
Partial laryngeal radiotherapy was associated with potentially favorable oncologic outcomes and toxic effects profiles compared to whole laryngeal radiotherapy. ja.ma/4rmjDmE
November 26, 2025 at 12:00 PM
Observation by general practitioners after pediatric ventilation tube surgery is noninferior to routine ENT specialist follow-up for hearing outcomes at two years. ja.ma/4rmIM0S
November 24, 2025 at 12:00 PM
Among patients with vestibular schwannoma, elevated anxiety was associated with greater self-reported dizziness severity. ja.ma/4oP68KJ
November 22, 2025 at 12:00 PM
A 62-year-old man with submandibular salivary duct history, alcohol use disorder, and facial flushing after minimal alcohol presents with lower extremity numbness, dysesthesia, and impaired proprioception.

What is your diagnosis? ja.ma/4psymuN
November 21, 2025 at 12:00 PM
Persistent cochlear microphonic amplitude drops during #CochlearImplant surgery were associated with reduced residual hearing, supporting real-time automated #Electrocochleography monitoring. ja.ma/4plZonA
November 20, 2025 at 4:30 PM
This longitudinal study highlights EVA as a genetically mediated inner ear malformation with heterogeneity in hearing loss severity, progression, and associated symptoms. ja.ma/3LPOFmL
November 20, 2025 at 1:00 PM
Mouth ulcers are painful sores that can appear anywhere inside of your mouth.

This JAMA Otolaryngology–Head & Neck Surgery Patient Page describes the causes, types, and treatment for mouth ulcers. ja.ma/486JPZW
November 18, 2025 at 2:00 PM
Adenotonsillectomy may be effective for young children with mild to moderate obstructive sleep apnea (OSA), whereas children with mild OSA and small tonsils could be recommended watchful waiting. ja.ma/49YnbW1
November 18, 2025 at 12:00 PM
While balloon sinuplasty was performed in just 2.7% of newly diagnosed Medicare patients with chronic or recurrent acute rhinosinusitis, 1.5% of otolaryngologists performed nearly half of all procedures. ja.ma/4qXGJQp
November 17, 2025 at 2:00 PM
A 13-year-old male presented with a 7-month history of a painless, progressively enlarging mass in the right parotid region. What is your diagnosis? ja.ma/47IlP0j
November 16, 2025 at 2:00 PM
Salivary Lachnoanaerobaculum spp may serve as a prognostic biomarker for improving treatment outcomes in patients with head and neck squamous cell carcinoma. ja.ma/4r26xLe
November 16, 2025 at 12:00 PM
Nearly one-third of US otolaryngologists performing balloon sinus dilation were classified as outliers, with over 10% of their procedures lacking timely preoperative CT scans. ja.ma/4qZLtFl
November 15, 2025 at 2:00 PM
This review summarizes recent deep learning advances in otolaryngology, including diagnostic models with expert-level accuracy for nasopharyngeal carcinoma and otologic pathology. ja.ma/48cV1oY
November 14, 2025 at 4:21 PM