Jamie Hanson
@jamielarsh.bsky.social
Psychology & Neuroscience Researcher at Pitt & LRDC | Studying the Impact of Early Life #Adversity on 🧠 Development | #Stress | Reposts ≠Endorsements
And... Early identification of youth with persistently low positive affect could enable targeted interventions focused on enhancing positive emotional experiences-- before depressive symptoms fully emerge.
Full paper (open access): acamh.onlinelibrary.wiley.com/doi/10.1111/... 5/5
Full paper (open access): acamh.onlinelibrary.wiley.com/doi/10.1111/... 5/5
a man is standing in front of a sign that says believe on it .
ALT: a man is standing in front of a sign that says believe on it .
media.tenor.com
January 15, 2026 at 2:50 PM
And... Early identification of youth with persistently low positive affect could enable targeted interventions focused on enhancing positive emotional experiences-- before depressive symptoms fully emerge.
Full paper (open access): acamh.onlinelibrary.wiley.com/doi/10.1111/... 5/5
Full paper (open access): acamh.onlinelibrary.wiley.com/doi/10.1111/... 5/5
Notably-- Persistently LOW positive affect specifically mediated the link between adversity → internalizing symptoms (depression/anxiety), but NOT externalizing problems.
This suggests distinct mechanistic pathways rather than general psychopathology risk. 4/5
This suggests distinct mechanistic pathways rather than general psychopathology risk. 4/5
January 15, 2026 at 2:50 PM
Notably-- Persistently LOW positive affect specifically mediated the link between adversity → internalizing symptoms (depression/anxiety), but NOT externalizing problems.
This suggests distinct mechanistic pathways rather than general psychopathology risk. 4/5
This suggests distinct mechanistic pathways rather than general psychopathology risk. 4/5
The stark reality...
As early life adversity increases, probability of staying in the High-Stable group drops from ~25% to just 4-8.5%. Meanwhile, Declining trajectory membership rises to 65-70% at highest adversity levels. 3/5
As early life adversity increases, probability of staying in the High-Stable group drops from ~25% to just 4-8.5%. Meanwhile, Declining trajectory membership rises to 65-70% at highest adversity levels. 3/5
January 15, 2026 at 2:50 PM
The stark reality...
As early life adversity increases, probability of staying in the High-Stable group drops from ~25% to just 4-8.5%. Meanwhile, Declining trajectory membership rises to 65-70% at highest adversity levels. 3/5
As early life adversity increases, probability of staying in the High-Stable group drops from ~25% to just 4-8.5%. Meanwhile, Declining trajectory membership rises to 65-70% at highest adversity levels. 3/5
Using person-centered trajectory modeling in 7,457 youth from the ABCD-study, we identified:
High-Stable (28%)
Declining (25%)
Persistently Low (24%)
Volatile (23%)
Rather than assuming everyone responds the same way to adversity, we let the data reveal natural subgroups. 2/5
High-Stable (28%)
Declining (25%)
Persistently Low (24%)
Volatile (23%)
Rather than assuming everyone responds the same way to adversity, we let the data reveal natural subgroups. 2/5
a woman in a floral jacket is making a gesture with her hands and smiling .
ALT: a woman in a floral jacket is making a gesture with her hands and smiling .
media.tenor.com
January 15, 2026 at 2:50 PM
Using person-centered trajectory modeling in 7,457 youth from the ABCD-study, we identified:
High-Stable (28%)
Declining (25%)
Persistently Low (24%)
Volatile (23%)
Rather than assuming everyone responds the same way to adversity, we let the data reveal natural subgroups. 2/5
High-Stable (28%)
Declining (25%)
Persistently Low (24%)
Volatile (23%)
Rather than assuming everyone responds the same way to adversity, we let the data reveal natural subgroups. 2/5