You have control over your feed, here and on mastodon. I too am needing a reprieve from depression, so I cultivated that. You could also split content to different feeds if there are friends you want to follow but not deal with daily.

this is art

Con: though it's vastly better than Facebook and Twitter, Bluesky is still a for-profit company, technically a Public Benefit Corporation which means accountable to both stockholders and public mission. But seed money is never free; promises are vague. In this regard, Mastodon has the high ground.

Con: blocklists are also sometimes made in bad faith, so that you think you're blocking one type of user, but actually a bad actor has stuck in maybe the opposite.

Of course, all this 3rd party stuff is fundamentally hard, so to some extent it will always be caveat emptor.

Con: it is hard to tell which accounts are fake. There is an inundation of fake accounts, to the point where the search button loses its purpose. If person is famous, there will be dozens of fake accounts that look like the real one. If not famous, and only one search result, still might be fake.

Con: 300 char limit--I understand the purpose, and will strive to be brief. But the thing that needed a couple paragraphs becomes a reply thread. Is frustrating, am ambivalent.

Pro: related to the last one, the idea that you are allowed to just see your feed in sequential order, so you can see what's new and be done, without the facebook-style abusive hell of endless scrolling trying to make sure you don't miss something important from someone you care about.

Pro: you can have multiple feeds, and control the order they are shown, e.g. one for Science, one for Linux, one for Art. There's an "OnlyFrom" feed which shows you just the post directly written by people you follow (i.e. not boosting/reposting) for when you're in a hurry.

Pro: some escape from the walled garden--you can get a link to your post and use that URL elsewhere, and people can click and view your post without having to become bluesky subscribers. Similar to Mastodon in that regard. Hope the intent is for it to always be thus.

Pro: you can subscribe to third party moderation labelers. For example, if you feel strongly about AI-generated images they have a labeling service for that. I do like seeing a warning.

Pro: user-specified moderation policy. They have built-in labels for things like NSFW, disinformation, impersonation, hate speech etc. But you can go into your profile and specify your personal policy for each one, e.g. warn me about NSFW but block hate speech completely.

Pro: a separate marketplace of blocklists, e.g. if you don't really want to deal with scammers or MAGA people, there are lists maintained by independent people and you choose which ones to subscribe to and whether to block or just mute.

Pro: nice feature implementation velocity. I like that for instance you can edit and expose your own starter packs of personal suggestions. Here's mine:
go.bsky.app/7TAoCxQ