Jorge C.
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jchc357.bsky.social
Jorge C.
@jchc357.bsky.social
11 followers 230 following 1 posts
||mathematical biology|who cares||
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Reposted by Jorge C.
teresaomeara.bsky.social
Candida albicans is usually hanging out with bacterial neighbors, so what happens to the fungus during co-culture?
The bacteria secrete metabolites that induce massive cell wall remodeling that change immune recognition and drug resistance. Read more in our new paper: www.cell.com/current-biol...
graphical abstract. Left is a fungal cell surrounded by bacteria, and the Hog1 cascade is turned on. Right is a fungal cell covered in mannan fibrils that prevent IgA and caspofungin and increase CLR recognition by macrophages
January 20, 2026 at 2:10 PM
jchc357.bsky.social
Sí soy…
soynormal.bsky.social Ache @soynormal.bsky.social · 11h
-¿Qué son estas piedras?
-Sirven para ahuyentar lo tóxico y las energías negativas
-¿Cómo funcionan?
-Tirándoselas a la gente dañina
January 21, 2026 at 2:40 PM
Reposted by Jorge C.
plosbiology.org
Immunometabolism is often disrupted in #cancer, suggesting it could be useful target for therapy. Heidi Ling &co @hkusbms.bsky.social explore the potential for incorporating #lifestyle changes and drug therapies that target #immunometabolism into treatments for cancer.
🧪 #immunosky
Targeting immunometabolism in cancer through pharmacological and lifestyle interventions
Immunometabolism is often disrupted in diseases such as cancer, suggesting it could be useful target for therapy. This Essay explores the potential for incorporating both lifestyle changes and drug…
plos.io
January 21, 2026 at 2:05 PM
Reposted by Jorge C.
plosbiology.org
Cochlear hair cell #stereocilia bundles are vital for hearing, but what is their 3D morphology? @manorlaboratory.bsky.social present VASCilia, a tool that automates analysis of 3D #ConfocalMicroscopy datasets of phalloidin-stained #CochlearHairCell bundles @plosbiology.org 🧪 plos.io/3NSHdYW
The algorithm successfully detects stereocilia bundles in 2D across successive frames, assigning unique IDs to each detected object within the 2D plane (left). The variation in IDs across frames reflects the independent detection process in each 2D frame. Subsequently, a multi-object assignment algorithm (middle) intervenes to reconcile these IDs, effectively re-assigning them to maintain consistency across frames. This step is crucial for reconstructing accurate 3D objects (right), ensuring that each bundle retains a consistent ID throughout all frames.
January 21, 2026 at 1:55 PM
Reposted by Jorge C.
biorxivpreprint.bsky.social
Amyloid precursor protein interacts with the mitochondrial phosphatase PGAM5 and regulates mitochondrial respiration https://www.biorxiv.org/content/10.64898/2026.01.20.700642v1
January 21, 2026 at 12:15 PM
Reposted by Jorge C.
sebbm.bsky.social
🌟#ArticulodelMes
 ¡Descubre el camino de la multimerización del receptor de glucocorticoides! Un análisis que arroja luz sobre sus mecanismos y funciones por el grupo de @Eva46653369 
📖👉 https://f.mtr.cool/dgvcgimbao
January 21, 2026 at 12:28 PM