Lightnews — Scholar-powered news

Jessica Nordlund @jessie-no.bsky.social · Aug 29

@scilifelab-ngi.bsky.social in collaboration with #Illumina are hosting a series of seminars on the topic of multiomics.
Come and join us in Stockholm (Sept 22) or Uppsala (Sept 23). More information and links to sign-up: tinyurl.com/yc7xjce5

#multiomics #illumina #scilifelab #ngi #genomics #ngs #spatialtranscriptomics #singlecell #proteomics #epigenomics #biotech #lifescience #research #stockholm #uppsala | SciLifeLab National Genomics In...

🧬 𝗜𝗹𝗹𝘂𝗺𝗶𝗻𝗮 𝗠𝘂𝗹𝘁𝗶𝗼𝗺𝗶𝗰𝘀 𝗗𝗮𝘆: 𝗖𝗵𝗼𝗼𝘀𝗲 𝗬𝗼𝘂𝗿 𝗖𝗶𝘁𝘆! 🧬 The future of integrated biology is here! Illumina and SciLifeLab National Genomics Infrastructure - NGI are hosting two Multiomics Day events in Septem...

tinyurl.com

3 4

Jessica Nordlund @jessie-no.bsky.social · Aug 20

Come and work with us! Great team and exciting tech!

Tuuli Lappalainen @tuuliel.bsky.social · Aug 19

A postdoc position in genomics available at our infrastructure in Uppsala, Sweden! An interesting R&D role a bit outside the traditional academic environment, great colleagues, work at the forefront of (long-read) sequencing.

www.uu.se/en/about-uu/...

Postdoctoral position - Uppsala University

Postdoctoral position, Department of Immunology, Genetics and Pathology, Uppsala University

www.uu.se

1 2

Reposted by Jessica Nordlund

Nikolay Oskolkov @oskolkov.bsky.social · Jul 18

I am starting a computational lab at LIOS, Riga, Latvia, and going to recruit a few people. Please DM if you are interested in a postdoc or PhD position in my Metabolic Research Group within the TARGETWISE project. I can highly recommend Riga, it is a beautiful city with very good living conditions.

30 35

Jessica Nordlund @jessie-no.bsky.social · Aug 4

Happy to share a paper from our lab out in @hemasphere-journal.bsky.social

-Resistance to antimetabolites, glucocorticoids & doxorubicin = poorer relapse-free survival
-Molecular profiling reveals pre-treatment resistance signatures

Huge thanks to all the co-authors and funders for their support

doi.org

1 1 4

Jessica Nordlund @jessie-no.bsky.social · May 29

We think this will drastically improve the interpretatability and utility of this type of data in future clinical applications.

Jessica Nordlund @jessie-no.bsky.social · May 29

n this paper, Mariya adapted a conformal prediction framework to three different ALL RNA-seq classifiers, for the first time enabling us to provide more precise measurements of when the classifiers are uncertain.

1

Jessica Nordlund @jessie-no.bsky.social · May 29

How much can we trust the classification scores? How sure are we that they are correct?

1

Jessica Nordlund @jessie-no.bsky.social · May 29

Check out the latest paper from our lab- here we tackled a problem that has been bothering me for over a decade, since we published our first gene-expression and DNA methylation ML-based subtype classifiers for pediatric ALL …

Mariya Lysenkova Wiklander @mariya.io · May 29

Our paper on conformal prediction for leukemia classification is now published. Our goal: provide statistical guarantees for machine learning, improving reliability and interpretability.

Read it here: doi.org/10.1200/CCI-...

#ConformalPrediction #Leukemia #MachineLearning #AIinMedicine

Error Reduction in Leukemia Machine Learning Classification With Conformal Prediction | JCO Clinical Cancer Informatics

PURPOSERecent advances in machine learning have led to the development of classifiers that predict molecular subtypes of acute lymphoblastic leukemia (ALL) using RNA-sequencing (RNA-seq) data. Althoug...

doi.org

1 1 4

Jessica Nordlund @jessie-no.bsky.social · May 16

Link: ilmn.ly/epigenetics-2025

Summary - Epigenetics: the full picture 2025

ilmn.ly

1

Jessica Nordlund @jessie-no.bsky.social · May 16

Registration is open for #Illumina "Epigenetics: the full picture” – free virtual event dedicated entirely to epigenetics on May 21-22. I had the honor to discuss opportunities and challenges from the Core facility perspective with the amazing @nadiasedl.bsky.social. Follow the link to register 🧬

1 2

Jessica Nordlund @jessie-no.bsky.social · May 13

There is still time to apply for this great postdoc opportunity

Jessica Nordlund @jessie-no.bsky.social · Apr 25

We’re hiring! Join us at the @scilifelab-ngi.bsky.social in Uppsala, Sweden

We're looking for a postdoc with a passion for -omics technology development to join our R&D team. This is a unique opportunity to work at the forefront of genomics and contribute to advancing cutting-edge sequencing tech!

Postdoctoral Researcher, NGI Uppsala, SNP&SEQ Technology Platform - Uppsala University

Postdoctoral Researcher, NGI Uppsala, SNP&SEQ Technology Platform, Department of Medical Sciences, Uppsala University

www.uu.se

1

Reposted by Jessica Nordlund

Jessica Nordlund @jessie-no.bsky.social · Apr 25

We’re hiring! Join us at the @scilifelab-ngi.bsky.social in Uppsala, Sweden

We're looking for a postdoc with a passion for -omics technology development to join our R&D team. This is a unique opportunity to work at the forefront of genomics and contribute to advancing cutting-edge sequencing tech!

Postdoctoral Researcher, NGI Uppsala, SNP&SEQ Technology Platform - Uppsala University

Postdoctoral Researcher, NGI Uppsala, SNP&SEQ Technology Platform, Department of Medical Sciences, Uppsala University

www.uu.se

7 6

Jessica Nordlund @jessie-no.bsky.social · Apr 25

We’re hiring! Join us at the @scilifelab-ngi.bsky.social in Uppsala, Sweden

We're looking for a postdoc with a passion for -omics technology development to join our R&D team. This is a unique opportunity to work at the forefront of genomics and contribute to advancing cutting-edge sequencing tech!

Postdoctoral Researcher, NGI Uppsala, SNP&SEQ Technology Platform - Uppsala University

Postdoctoral Researcher, NGI Uppsala, SNP&SEQ Technology Platform, Department of Medical Sciences, Uppsala University

www.uu.se

7 6

Jessica Nordlund @jessie-no.bsky.social · Feb 25

That might be a challenge?!?

1

Reposted by Jessica Nordlund

Alex Hoischen @ahoischen.bsky.social · Feb 23

Wow! #AGBTGM #AGBT25 #AGBT2025 just kicked off by Bill Clinton!
„…the human genome project was the best $3 billion tax money ever spent…“

11 39

Reposted by Jessica Nordlund

Jasmine Plummer @jasmineplummer.bsky.social · Feb 22

FOMO on all the cool science & tech at #AGBT25. on Feb 28th, we’re spilling all the beans on our fave developments in #ngs #spatial #multiomics #singlecell. Register: www.genengnews.com/multimedia/g... @jlemieux.bsky.social @biomath.bsky.social @catharineaquino.bsky.social @jessie-no.bsky.social

Managing Multiple Biomarker Therapeutic Development

On this episode of GEN Live, we’ll give you a full AGBT breakdown. Experts from the NGS, single cell, and spatial fields join the show to review and dissect this year’s announcements. We’ll cover the ...

www.genengnews.com

6 11

Reposted by Jessica Nordlund

coregenomics.bsky.social @coregenomics.bsky.social · Feb 14

Hi everyone on Bluesky working in #genomics #NGS. Today is Valentines day. How many of you are more excited about Feb 20th?!

Read my new post on Enseqlopedia Roche emerges from the Lazarus pit to take on Illumina

enseqlopedia.com/2025/02/roch...

Roche emerges from the Lazarus pit

Is Roche going to "knock it out of the park" or "jump the shark"? Everyone I know is excited, even if many of them are sceptical, about the Feb 20th webinar and what we will learn about SBX. Alex Dick...

enseqlopedia.com

2 6 10

Jessica Nordlund @jessie-no.bsky.social · Feb 12

Loads of single cells!!!! @scilifelab-ngi.bsky.social

SciLifeLab National Genomics Infrastructure - NGI @scilifelab-ngi.bsky.social · Feb 12

Today Henrik & Abrahan from our single-cell team hosted @parse.bsky.social in our newly launched NGI OpenLab. If you're interested in finding out more about the OpenLab or #singlecell applications available at NGI please, check the link 🧬🧪

4

Jessica Nordlund @jessie-no.bsky.social · Jan 29

Congrats to @dbergerbiol.bsky.social and team for this important study... and FYI your RNA was beautiful 🤩

SciLifeLab @scilifelab.se · Jan 29

“RNA quality is a significant challenge, especially when working with insect samples … To overcome this, careful sample collection and handling procedures are essential” says @jessie-no.bsky.social at @scilifelab-ngi.bsky.social 🧪🌍

More about the technique here ↓
www.scilifelab.se/news/pest-mo...

Agricultural loss from pests is underestimated – models are missing evolutionary processes

Pest adapted to increasing temperatures that focus on surviving rather than reproducing, is more successful in both – creating a double blow for the crops they eat.

www.scilifelab.se

1 1 3

Jessica Nordlund @jessie-no.bsky.social · Jan 28

Check out @mindymandy.bsky.social 's latest publication- testing the utility of Honeycomb Biotechnologies HIVE for single cell analysis of 🐎 samples from the equine clinic. 🧬🧪

Exploring a pico-well based scRNA-seq method (HIVE) for simplified processing of equine bronchoalveolar lavage cells

Single-cell RNA sequencing (scRNA-seq) is a valuable tool for investigating cellular heterogeneity in diseases such as equine asthma (EA). This study evaluates the HIVE™ scRNA-seq method, a pico-well-...

journals.plos.org

2

Jessica Nordlund @jessie-no.bsky.social · Jan 20

We're thrilled to see how NGI OpenLab will support the SciLifeLab genomics community, and we welcome your ideas for new equipment or initiatives to make this space even better.

1

Jessica Nordlund @jessie-no.bsky.social · Jan 20

Whether you're running experiments or exploring cutting-edge genomics tools, NGI OpenLab provides an accessible, well-equipped environment to accelerate your discoveries.

1 1

Jessica Nordlund @jessie-no.bsky.social · Jan 20

On January 16th @scilifelab-ngi.bsky.social officially launched the NGI OpenLab, an innovative space designed to empower genomics researchers.

Now part of the SciLifeLab ecosystem in Uppsala, OpenLab bridges the gap between our genomics core services and the unique needs of the research community.

1 2 5

Reposted by Jessica Nordlund

Ewan Birney @ewanbirney.bsky.social · Jan 15

Bit of a standard moan - “epigenetic association studies” are *very* hypothesis / model different vs GWAS (genotype association studies) even though the process v similar (put DNA on arrays, call alleles/epi-alleles, do association with covariates). *completely* different

3 19 51

Jessica Nordlund @jessie-no.bsky.social · Jan 8

We have for the B-cell ALL Reh cell line: www.life-science-alliance.org/content/7/8/...

A multiomic characterization of the leukemia cell line REH using short- and long-read sequencing

The B-cell acute lymphoblastic leukemia (ALL) cell line REH, with the t(12;21) ETV6::RUNX1 translocation, is known to have a complex karyotype defined by a series of large-scale chromosomal rearrangem...

www.life-science-alliance.org

1 1