José L. McFaline-Figueroa
@jlmcfalinefigueroa.bsky.social
74 followers 260 following 4 posts
Assistant Professor, BME, Columbia University
Posts Media Videos Starter Packs
Reposted by José L. McFaline-Figueroa
cancerdynamics.bsky.social
October newsletter is out. Watch the latest Faces of IICD interview, read about the latest breast cancer research highlights and the GROW conference, and more.

cancerdynamics.columbia.edu/news/iicd-ne...

#BreastCancerAwareness @nygenome.org @elhamazizi.bsky.social @jlmcfalinefigueroa.bsky.social
IICD Newsletter October 2025
jlmcfalinefigueroa.bsky.social
We’re hiring!📣

Exciting opportunity at the Irving Institute for Cancer Dynamics and School of Engineering and Applied Science at Columbia: Associate Research Scientist. Lead pooled CRISPR + Perturb-seq screens to close AI-identified knowledge gaps. Apply apply.interfolio.com/172825
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
jlmcfalinefigueroa.bsky.social
Please reach out if you have questions!
jlmcfalinefigueroa.bsky.social
Please share!

The Irving Institute for Cancer Dynamics and the Fu Foundation School of Engineering & Applied Science at Columbia are seeking an Associate Research Scientist to design & execute pooled CRISPR and Perturb-seq screens. Apply here: apply.interfolio.com/172825
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
Reposted by José L. McFaline-Figueroa
eileen-furlong.bsky.social
To all post-docs: The Genome Biology dept ‪@embl.org
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Group Leader - Genome Biology Unit
Are you ready to lead groundbreaking research in Genome Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group addressing exciting and original biological...
embl.wd103.myworkdayjobs.com
jlmcfalinefigueroa.bsky.social
Wondeful collaboration! This study with the Shah lab (Columbia Chemistry), led by Anne Vlimmeren and Ross Giglio, profiled disease associated SHP2 variants, linking variant-specific changes in molecular programs with differences in structure and substrate specificity. Check it out!
nshahlab.bsky.social
Check out our latest preprint, from Anne van Vlimmeren in my group and Ross Giglio in @jlmcfalinefigueroa.bsky.social's lab. We used single-cell transcriptomics, biochemistry, and structural analysis, to reveal how mechanistically distinct SHP2 disease mutations yield different cellular states.
biorxiv-molbio.bsky.social
Multiplexed single-cell transcriptomics reveals diverse phenotypic outcomes for pathogenic SHP2 variants https://www.biorxiv.org/content/10.1101/2025.06.30.662374v1
Reposted by José L. McFaline-Figueroa
srikosuri.bsky.social
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.
Reposted by José L. McFaline-Figueroa
ritastrack.bsky.social
I wonder if spreading extremely encouraging experimental results on helping treat pancreatic cancer with *gasp* mRNA vaccines may help people who have villainized them come around. This is a good press release on the study and links to the Nature paper. www.mskcc.org/news/can-mrn...
In Early-Phase Pancreatic Cancer Clinical Trial, Investigational mRNA Vaccine Induces Sustained Immune Activity in Small Patient Group
Learn how MSK researchers are deploying mRNA vaccines against pancreatic cancer.
www.mskcc.org
Reposted by José L. McFaline-Figueroa
arghavansallesmd.medsky.social
Of the 4000 researchers at NIH, only 20% are tenured. They’re going to fire all the rest as their contracts come up for renewal, absolutely decimating research at the NIH. This is catastrophic, not just for Americans, but for the whole world.

www.science.org/content/arti...
NIH ban on renewing senior scientists adds to assaults on its in-house research
Policy follows firings of tenure-track scientists and suspension of training programs
www.science.org