Super cool! Do you have a sense of whether non-monotonicity in GDRCs depends on trait polygenicity? E.g. height vs a “trivial” trait like expression of an RNA, which might have a simpler linear relationship to gene dosage. Is there a continuum between these worlds?

I’m excited for my first preprint in the Good lab, a theory project predicting the first steps of evolution in microbial communities with resource competition. If you’re interested in how community context shapes the availability and impact of mutations, read on!

doi.org/10.1101/2023.12.15.571925