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Johannes Enevoldsen @johsenevoldsen.bsky.social · 10d

Ah 👌 det giver jo egentligt god mening. TIL

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Johannes Enevoldsen @johsenevoldsen.bsky.social · 10d

Ok. Mit eksempel var grammatisk forkert ☺️ " ... med dens krig"

Men er den oprindelige overskrift ikke stadig god nok?

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Johannes Enevoldsen @johsenevoldsen.bsky.social · 10d

Er det ikke korrekt? "dansker banker" er grundled i sætningen.

Sætningen kunne forsættes "... med deres krig"

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Reposted by Johannes Enevoldsen

michielstock.bsky.social @michielstock.bsky.social · Jun 18

Small blog post on how to automate model building for mechanical systems using ModelingToolkit. #julialang

michielstock.github.io/posts/2025/p...

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Reposted by Johannes Enevoldsen

Trish Greenhalgh @trishgreenhalgh.bsky.social · Jun 19

Thanks for the reminder @janemunday.bsky.social. Every summer, I repost this article DROWNING DOES NOT LOOK LIKE DROWNING. To date, I know of FOUR kids who were saved after someone who'd clicked on the link learnt how to spot actual drowning. Take time to read and pass on.

slate.com/technology/2...

Drowning Doesn’t Look Like Drowning

Drowning is not the violent, splashing call for help that most people expect.

slate.com

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Johannes Enevoldsen @johsenevoldsen.bsky.social · Jun 18

Great ... though it would have been nice to make this show 0✅

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Johannes Enevoldsen @johsenevoldsen.bsky.social · Jun 18

I have the same problem. If I only ever intend putting it on GitHub, is it reasonable to just ignore it? Escaping all these characters will make the code a lot less readable.

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Johannes Enevoldsen @johsenevoldsen.bsky.social · Jun 17

Thank you. With such praise, it is hard not to:
RSS: jenevoldsen.com/index.xml

jenevoldsen.com

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Johannes Enevoldsen @johsenevoldsen.bsky.social · Jun 13

It would be a reasonable regulatory mechanism, that lactate signals increased oxygen demand and raises CO, though I don't know whether it is possible, or even meaningful, to distinguish whether lactate is both fuel and a signal, or just fuel.

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Johannes Enevoldsen @johsenevoldsen.bsky.social · Jun 13

Just found that the same group also did this study, showing that lactate increases CO in healthy adults. pubmed.ncbi.nlm.nih.gov/39825426/

Cardiovascular effects of lactate in healthy adults - PubMed

https://clinicaltrials.gov/ct2/show/NCT04710875 . Registered 1 December 2020.

pubmed.ncbi.nlm.nih.gov

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Johannes Enevoldsen @johsenevoldsen.bsky.social · Jun 13

bsky.app/profile/johs...

Johannes Enevoldsen @johsenevoldsen.bsky.social · May 26

My cardiac arrhythmia simulation now also simulates how a reentrant loop can be terminated by increasing refractory time as suggested by @empoisonpharmd.bsky.social

Direct link to the updated part:
jenevoldsen.com/posts/excita...

Reposted by Johannes Enevoldsen

Lars Mølgaard Saxhaug @load-dependent.bsky.social · Jun 13

Absolutely fascinating! We know the heart switches to lactate as energy substrate in shock, could there be a clinical benefit from lactate infusion in human cardiogenic shock? #emimcc #cccsky

BMC @bmc.springernature.com · Mar 20

Lactate infusion enhances cardiac output and peripheral perfusion in ischemic cardiogenic shock without affecting heart rate or systemic blood pressure, finds a study published in Critical Care.

#MedSky

Lactate infusion improves cardiac function in a porcine model of ischemic cardiogenic shock

Critical Care

bit.ly

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Johannes Enevoldsen @johsenevoldsen.bsky.social · Jun 13

Incredible effect sizes. Do we know what lactate does in a healthy heart? From a teleological perspective, it would make sense that lactate has a positive inotropic effect, regardless of it being a substrate. Simply as a signal of hypoperfusion.

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Johannes Enevoldsen @johsenevoldsen.bsky.social · May 26

I'm sorry you had to experience that. Unfortunately I don't know what determines which treatment is tried first, or whether e.g. cardioversion can be expected to work if the condition reoccurs, when it didn't work the first time.

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Johannes Enevoldsen @johsenevoldsen.bsky.social · May 26

My cardiac arrhythmia simulation now also simulates how a reentrant loop can be terminated by increasing refractory time as suggested by @empoisonpharmd.bsky.social

Direct link to the updated part:
jenevoldsen.com/posts/excita...

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Reposted by Johannes Enevoldsen

Sam Rose @samwho.dev · May 8

✨ It's new samwho visual essay o'clock! ✨

Reservoir sampling is one of my favourite algorithms. It allows you to sample from a set without knowing the size of that set.

I try to assume no prior knowledge, and use no scary math notation. Just beautiful visuals.

Let me know what you think! ❤️

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Reposted by Johannes Enevoldsen

Ryan Feldman PharmD DABAT @empoisonpharmd.bsky.social · Apr 29

I just want to say I use this constantly at the bedside when dealing with patients who have arrythmias to explain how they propagate.

would LOVE LOVE a model where increasing refractory terminates reentrant rhythm so I can show how diltiazem terminates SVT.

such an amazing tool, thank you

Johannes Enevoldsen @johsenevoldsen.bsky.social · Feb 20

I wrote a short interactive article👆

It uses simulations to demonstrate how different cardiac arrhythmias can develop.

Try it out! (It has defibrillators ⚡️)

jenevoldsen.com/posts/excitable-cells

#medsky #cardiosky #cccsky #emimcc

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Johannes Enevoldsen @johsenevoldsen.bsky.social · Apr 29

Thank you! So nice to learn that it is actually read and used.

Good idea with a sim, where the arrhythmia is stopped with meds. It shouldn't be too hard to make a sim, where refractory time can be prolonged.

I'll give you a heads up when I find the time to implement it.

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Johannes Enevoldsen @johsenevoldsen.bsky.social · Apr 8

A 10-minute movie in a 6.3-second looping GIF.

Movie: Sprite Fright (#Blender open movie): studio.blender.org/projects/spr...

Code (#JuliaLang and @makie.org)
gist.github.com/JohannesNE/2...

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Johannes Enevoldsen @johsenevoldsen.bsky.social · Apr 2

For AVNRT, some people just have a physiological variant where the AV node is split in a slow pathway and a fast pathway.

For VF and AFib, there are many proposed mechanisms, slow repolarization could occur in areas with ischemia. Reduced conduction due to e.g. fibrosis plays a large role as well.

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Johannes Enevoldsen @johsenevoldsen.bsky.social · Apr 1

Thanks. Just scrolled through some of your articles. Really impressive! I look forward to doing a deeper dive in the coming days.

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Johannes Enevoldsen @johsenevoldsen.bsky.social · Apr 1

Thanks.

I'll add that next time I update it. Might be a while before post #2 though 😉

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Reposted by Johannes Enevoldsen

Guillaume Dalle @gdalle.bsky.social · Mar 11

Fellow #JuliaLang enthusiasts in Europe, I've got 4 words for you.

JuliaCon Local Paris 2025

Yes, it's happening. Like the global @juliacon.bsky.social event, but with more croissants. Stay tuned!

JuliaCon Local Paris 2025

juliacon.org

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Johannes Enevoldsen @johsenevoldsen.bsky.social · Feb 25

This would of course require a local LLM for privacy reasons.

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Johannes Enevoldsen @johsenevoldsen.bsky.social · Feb 25

- Why is this patient not on losartan?
- Has this pt with "COPD" ever done a pulmonary function test?
- What penicillin-like drugs has this pt with registered penicillin allergy received since the penicillin-associated rash 30 years ago?

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