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Excited to share our new paper in
@GeneticsGSA
! We developed "Retriever," a novel method that enables high-quality genotype imputation in non-model organisms. 🧬 Congratulations to Charles on his first PhD paper!

Paper: doi.org/10.1093/gene...

A thread 🧵👇

🦠💀🦠 Happy to share our (with @gunnar-u-neumann.bsky.social) new preprint on ancient Salmonella enterica genomes! We analysed 53 new genomes along with published ancient and modern datasets to learn about lineage replacements and host adaptation in prehistory: www.biorxiv.org/content/10.1...

🚀 We’re hiring a #Postdoc!
🔬 Join our group in Copenhagen to study Water Buffalo 🐃 #Population #Genomics
Highly motivated & enthusiastic candidates are welcome!

👉 **Apply:** candidate.hr-manager...

⏰Deadline Oct 15th 2025
#WaterBuffalo #Conservation #EvolutionaryBiology

Interested in goats 🐐? Read our pre-print on ancient Irish goats and their connection to the Old Irish goat breed

Just look at this dashing individual, courtesy of the Old Irish Goat society

Shameless promotion from #isba11 - I'll be hiring PhDs to start early 2026 (plus postdocs starting later), using #adna to study livestock and pathogen coevolution, particularly looking at inbreeding and immune gene evolution!

Contact me at kevin[at]palaeome.org, full ad to come. Please share!

My student Louis L'Hôte presenting his work on ancient sheeppox virus at #isba11 #aDNA

Interested in measuring genetic load? We have a new paper out providing a modified version of GERP which is more user friendly in wildlife species and with scripts to automate making input files and pulling out derived alleles in your species #consgen #popgen star-protocols.cell.com/protocols/4202

Postdoctoral Position in Wildlife Palaeogenomics!

Come join us in beautiful Stockholm!

su.varbi.com/en/what:job/...

Inferring domestic goat demographic history through ancient genome imputation https://www.biorxiv.org/content/10.1101/2025.04.18.649576v1

Our results demonstrate that genotype imputation is a valuable tool for maximizing information from low-coverage goat palaeogenomes.

This approach offers new opportunities to investigate the genetic impacts of early domestication and herd dispersal—directions we will be continuing to explore!

Identity-by-descent (IBD) patterns mirrored our ROH findings: Goats from early herding sites like Ganj Dareh exhibited less relatedness compared to goats from later in the dispersal process.

#Mobility #Domestication​

📊 Insights into early goat domestication:
Analyzing 36 previously published ancient goat genomes, we observed that runs-of-homozygosity (ROH) increased with distance from the Zagros Mountains during the Neolithic, suggesting effects from the initial dispersal of managed herds.

#Neolithic #Goats​

By imputing ancient downsampled genomes utilizing the VarGoats dataset (www.goatgenome.org/vargoats.html), we achieved high concordance at 0.5× coverage for common variants.

🐐 New preprint out with @gingerhowley.bsky.social The VarGoats Consortium and many others!
We explore how genotype imputation can enhance low-coverage ancient goat/Capra🐐 genomes, shedding light on early domestication and herd management.

www.biorxiv.org/content/10.1...

#aDNA #Domestication​

A final request for those involved in the Ancient Biomolecule Communities: If you follow the activities of AaRC, HAAM, PAASTA, SPAAM and LAARD, help us improve our understanding of our communities with this short survey!

#aDNA #palaeoproteomics #biomoleculararchaeology #ZooMS #ancientDNA

@jolijnerven.bsky.social @facultyofartsug.bsky.social @tcddublin.bsky.social unlocks the origins of domesticated pigs how they related to wild boar and people in the Dutch wetlands 6000 years ago An nwo project @unigroningen.bsky.social @w-u-r.bsky.social
W implications for #morethanhuman life

We found that during the Neolithic, pig management in Europe was highly variable. By integrating paleogenomics and zooarchaeology, we uncovered a commensal relationship between humans, pigs and wild boar at the Early Neolithic settlement of Swifterbant

Interested in human-pig-boar interactions? Read our new paper on human-pig-boar relationships in Neolithic Europe 🐷🐗🧬.

www.pnas.org/doi/10.1073/...

How did Europe's first farmers interact with their pigs and local wild boar? @jolijnerven.bsky.social has a new paper addressing just that using 11 ancient suis genomes!

www.pnas.org/doi/10.1073/...