jorg-vogel-lab.bsky.social
Jörg Vogel
@jorg-vogel-lab.bsky.social
150 followers 5 following 8 posts
RNA, microbiology, infectious disease; Helmholtz Institute for RNA-based Infection Research & University of Würzburg, Germany www.helmholtz-hiri.de
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jorg-vogel-lab.bsky.social
Jörg Vogel @jorg-vogel-lab.bsky.social · 27d
Sorry, no genetics
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jorg-vogel-lab.bsky.social
Jörg Vogel @jorg-vogel-lab.bsky.social · 27d
We should talk again how to use your AI power to find the right CPPs for ASO delivery into those many bacteria with cool phages but no bacteria
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jorg-vogel-lab.bsky.social
Jörg Vogel @jorg-vogel-lab.bsky.social · 28d
Looking for a new approach to studying or eliminating phages? Check out our study introducing anti-phage ASOs (antisense oligos) out in @Nature today. nature.com/articles/s4158…
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jorg-vogel-lab.bsky.social
Jörg Vogel @jorg-vogel-lab.bsky.social · May 5
And this only the beginning! I’m glad we did that collaboration with the Maric lab. ASOs for the people!
giorgiadanti.bsky.social
Giorgia Danti @giorgiadanti.bsky.social · May 5
First post, first paper 🤭
Proud to share with all of you our work on mRNA blocking using our own high-throughput antisense approach! doi.org/10.1002/advs...

Many thanks to @hmariclab.bsky.social, @jorg-vogel-lab.bsky.social and especially Linda for the amazing collaboration 😸
High‐Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics
The systematic tiling of essential genes’ mRNA here presented, proposes a valuable tool for the identification of novel PNA sequences with antibiotic potential. The high-throughput synthetic set up o...
doi.org
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jorg-vogel-lab.bsky.social
Jörg Vogel @jorg-vogel-lab.bsky.social · Apr 16
The Helmholtz RNA & Infection building getting ever more interesting, with the staircase unfolding. So many different levels, it looks a bit like downtown Bangkok to me, if you know what I mean.
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jorg-vogel-lab.bsky.social
Jörg Vogel @jorg-vogel-lab.bsky.social · Apr 9
First trip to the beer garden by the river with the lab and friends of the lab this year. Mixed feelings because it’s the farewell of Suyen Espinoza who’s leaving for a new job with a great pharmaceutical company. It’s hard to let go of her for many reasons, my first postdoc ever from Nicaragua!
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jorg-vogel-lab.bsky.social
Jörg Vogel @jorg-vogel-lab.bsky.social · Apr 9
If you want to do single-cell RNA-seq on your favourite bacterium, here‘s our detailed Nature Protocol for microbial MATQ-seq. It profiles up to 600 genes in a single bacterial cell!

www.nature.com/articles/s41...
Transcriptomic profiling of individual bacteria by MATQ-seq - Nature Protocols
Bacterial single-cell sequencing via MATQ-seq combines index sorting, random priming and rRNA depletion, and offers high cell retention and transcript capture rates, making it ideal for experiments wi...
www.nature.com
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jorg-vogel-lab.bsky.social
Jörg Vogel @jorg-vogel-lab.bsky.social · Apr 4
Finally made it to Bluesky as well. Here’s the me Helmholtz RNA & Infection building as of this week.
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