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The Journal of Physiology @jphysiol.bsky.social · 15h

Recent #Research by Jadwiga N. Bilchak of pennmedicine.bsky.social et al. finds that #KCC2 enhancers normalize reflex responses and improve #locomotor function after chronic spinal cord injury 🧠 ⚙️

📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

The Journal of Physiology @jphysiol.bsky.social · 16h

🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...

The endogenous circadian system impairs nighttime blood pressure responses to active standing in older adults

Abstract figure legend Compared to midlife adults, older adults have an impaired blood pressure response to active standing. These differences are exacerbated during the night, which may increase the...

physoc.onlinelibrary.wiley.com

The Journal of Physiology @jphysiol.bsky.social · 16h

In this study, Filip Ježek of charlesuni.cuni.cz et al. performed theoretical analysis of power-law stress relaxation and calcium-dependent passive #mechanics in #cardiac muscle 🫀 ⚙️

📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

The Journal of Physiology @jphysiol.bsky.social · 18h

🎓 EDITOR'S CHOICE🎓

#Research by Saurabh Suhas Thosar & Steven A. Shea of @occhealthsci.bsky.social observes that elderly humans show an impaired blood pressure adaptation to arising from bed during the nighttime.

📜 🔗https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP289266

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The Journal of Physiology @jphysiol.bsky.social · 1d

Paolo Spaiardi et al. found that transient capacitance changes recorded from vestibular type I hair cells are produced by GK,L gating and do not involve #neurotransmitter exocytosis 🧠 💉

📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...

The Journal of Physiology @jphysiol.bsky.social · 1d

#Research by Bettina K. M. Firmke of uniregensburg.bsky.social et al. found that #hypoxia-inducible factor-2 stabilization is not sufficient to induce erythropoietin production in deeper medullary #fibroblasts 🔬 📜

🔗 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Reposted by The Journal of Physiology

The Journal of Precision Medicine: Health and Disease @jprecmed.bsky.social · 2d

📣 CALL FOR PAPERS📣

Examining New Approach Methodologies #NAMs in #precisionmedicine 💉🔎

Submit by 28 February 2026 ⏰

🔗 For topics and more information:

www.sciencedirect.com/special-issu...

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The Journal of Physiology @jphysiol.bsky.social · 2d

In a recent study, Alexey V. Dvornikov & Samantha P. Harris of uarizona.bsky.social observed that #myosin-binding protein C slows #cardiac myofibril relaxation kinetics 🫀 💉

📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

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The Journal of Physiology @jphysiol.bsky.social · 2d

📣 Call for Papers📣

For the special issue "Placental and fetal brain interfaces: how effective are they in protecting against drugs and toxins?" 🧠 💊

⏰ Deadline: 15 October 2025

🔗 For more information & how to submit: physoc.onlinelibrary.wiley.com/hub/journal/...

The Journal of Physiology @jphysiol.bsky.social · 2d

Leah S. Halls of ugaresearch.bsky.social et al. observed that #dihydrosterculic acid induces #hepatic PPARα target gene expression in mice 🧬 🔎

📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...

The Journal of Physiology @jphysiol.bsky.social · 5d

This #Perspective by Sandra K. Hunter examines #testosterone and androgen receptors in females, based on research by Alexander et al. (2025) ✍️

🔗 Available here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

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The Journal of Physiology @jphysiol.bsky.social · 5d

Recent #Research by Guillaume P. Ducrocq et al. finds that GsMTx-4 inhibits the #exercise pressor reflex and the muscle #mechanoreflex primarily through TRPC inhibition 🔎 🔬

📜 🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

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The Journal of Physiology @jphysiol.bsky.social · 5d

Dayna A. Zimmerman et al. observed that #metformin and #insulin exacerbate one-carbon metabolism deficits in #pregnant growth restricted rats and impacts the placenta, fetal liver and pancreas 💉 🔎

📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

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The Journal of Physiology @jphysiol.bsky.social · 6d

Andrew W. D'Souza & Michael K. Stickland discuss the work of Sayegh et al. (2025) examining peripheral chemoreflex constraint of skeletal muscle blood flow ✍️

Read the #Perspective here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Reposted by The Journal of Physiology

The Journal of Precision Medicine: Health and Disease @jprecmed.bsky.social · 6d

This #Review article by Khaoula El Mekkaoui (of ucdavis.bsky.social, vtt.fi & csaalto.bsky.social) et al. examines the impact of the social exposome in #cardiovascular health and disease 🫀📖

🔗 Read the #OpenAccess article here: www.jprecisionmedicine.org/article/S305...

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The Journal of Physiology @jphysiol.bsky.social · 6d

Hsuan-Yu Wan et al. investigated regional cerebral perfusion and sympathetic activation during exercise in #hypoxia and #hypercapnia, offering preliminary insight into ‘Cushing's mechanism’ ⚙️ 🧠

📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

The Journal of Physiology @jphysiol.bsky.social · 6d

Sergi Garcia-Retortillo & Plamen Ch Ivanov investigated the dynamics of #cardio-muscular networks in exercise and #fatigue 🫀🏃

📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...

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The Journal of Physiology @jphysiol.bsky.social · 7d

Our latest issue is now live!🎉

Featuring cover art from Thomasi et al. that shows calcium activity over time among cholinergic enteric #neurons in neurocircuits that control #gut motor function.

📖 🔗 Access the issue here: physoc.onlinelibrary.wiley.com/toc/14697793...

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The Journal of Physiology @jphysiol.bsky.social · 7d

Ann-Katrin Grotle & Audrey J. Stone present this #Perspective on the work of Ducrocq et al. (2025) examining the mystery of the mechanically sensitive component of the exercise pressor reflex ✍️

🔗 Available here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

The Journal of Physiology @jphysiol.bsky.social · 7d

Ana Luiza C. Sayegh et al. found that peripheral #chemoreflex restrains skeletal muscle blood flow during exercise in participants with treated #hypertension 🔎 🫀

📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...

The Journal of Physiology @jphysiol.bsky.social · 7d

This study by Richard M. Bruce of kingscollegelondon.bsky.social et al. finds that incongruent #virtualreality cycling exercise demonstrates a role of perceived effort in #cardiovascular control 🫀 👓

📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/full/10....

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The Journal of Physiology @jphysiol.bsky.social · 8d

Nathan E. Bartman of brocku.ca et al. present this #JournalClub article on sensory deception during cycling based on the investigation by Bruce et al. (2025) ✍️ 🚴

🔗 Available here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

The Journal of Physiology @jphysiol.bsky.social · 8d

This study by Alec L. E. Butenas of kstate.bsky.social et al. observes that #protein kinase C epsilon contributes to chronic #mechanoreflex sensitization in rats with heart failure 🫀 🧠

📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

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The Journal of Physiology @jphysiol.bsky.social · 8d

Yu Huo of utexasglobal.bsky.social et al. observed that interleukin-1 type 1 receptor blockade attenuates the exaggerated #exercise pressor reflex in male UC Davis type 2 #diabetic mellitus rats 🧠🫀

📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/full/10....

The Journal of Physiology @jphysiol.bsky.social · 9d

❗Now extended to 1st December 2025⏰

The Journal of Physiology @jphysiol.bsky.social · 9d

📣 Call for Papers📣

⏰ Deadline: 1st October 2025 ⏰

For the special issue "Experimental and quantitative modelling approaches in cardiac and vascular physiology: focus on ion channels and Ca2+ regulation"

🔗 For more information & how to submit: physoc.onlinelibrary.wiley.com/hub/journal/...