Lightnews — Scholar-powered news

Reposted by Jun Axup

Andrew Payne @andrewcpayne.bsky.social · 7d

E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves.

Read more: e11.bio/blog/prism

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Jun Axup @junbio.bsky.social · Jun 10

People often ask how FROs started. Here's the origin story! Honored to be a part of this movement!

Convergent Research @convergentresearch.bsky.social · Jun 9

"Academic research groups and startups are essential drivers of scientific progress. But some projects, like the Hubble Space Telescope or the Human Genome Project, are too big for any one academic lab or loose consortium..."

Former MIT researchers advance a new model for innovation

Developed by former MIT researchers, focused research organizations (FROs) undertake large research efforts and have begun to contribute to scientific advances.

news.mit.edu

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Jun Axup @junbio.bsky.social · May 29

We launched our first open-source software package! 🔬🖥️🌈

E11 Bio @e11bio.bsky.social · May 29

E11 Bio is launching Volara: an open-source Python library for block-wise processing of large volumetric microscopy datasets! 🧪🔬

Volara features block-wise task abstractions, making scalable image processing more accessible, robust, and repeatable.

Read more: e11.bio/blog/volara

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Jun Axup @junbio.bsky.social · May 7

📢 I'm hiring a Chief of Staff for project management and operations! 🧬🌈🔬🧪

E11 Bio @e11bio.bsky.social · May 7

✨E11 Bio is hiring a Chief of Staff / Project Manager!

This unique role blends scientific project management with day-to-day operations—and gives you a front-row seat and bird’s-eye view as we advance the field of connectomics toward mammalian brains.

Job posting: jobs.lever.co/convergentre...

Convergent Research - E11 Bio - Chief of Staff / Project Manager

E11 Bio is on a mission to advance connectomics towards whole brain scale for humans and other mammals. We are a collaborative and interdisciplinary team of scientists and engineers engaged in a neuro...

jobs.lever.co

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Jun Axup @junbio.bsky.social · Mar 19

Focused Research Organizations mentioned in the @nytimes.com today as a promising path for bigger riskier ambitious science!

Convergent Research @convergentresearch.bsky.social · Mar 19

"Organizations like @hhmijanelia.bsky.social, the @arcinstitute.org, and a whole class of nonprofit start-ups called focused research organizations are instead using philanthropic dollars to build tools that could accelerate scientific progress."

www.nytimes.com/2025/03/19/o...

Opinion | DOGE Needs a Different Playbook for Science

We need less administrative bloat in science.

www.nytimes.com

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Jun Axup @junbio.bsky.social · Feb 9

A brief history and the future of mapping the brain! 🧠
Huge thanks to @asimovpress.bsky.social for sharing our work at @e11bio.bsky.social!

Asimov Press @asimovpress.bsky.social · Feb 9

Can we treat brain disorders by restoring neural connections?

For centuries, neuroscientists could only guess. But connectomics—a method seeking to create a 3D model of every neural connection in the brain—is moving closer to providing answers.

E11 Bio is at the forefront...🧵

Reposted by Jun Axup

Patrick Mineault @patrickmineault.bsky.social · Feb 9

Great long read on @e11bio.bsky.social by one of my favorite publications @asimovpress.bsky.social . It’s worth repeating: estimated cost for a whole mouse brain connectome has gone down by a factor 100 over the last couple of years. open.substack.com/pub/cell/p/b...

Barcoding Brains

Connectomics — a technique that maps physical connections between neural cells — is expensive and inefficient. E11 Bio, a non-profit research group, is designing a tool to expedite progress.

open.substack.com

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Jun Axup @junbio.bsky.social · Feb 5

Help us make beautiful brain data! 🧠🌈🧪 We are hiring an Image Data Scientist and RA!

Johan Winnubst @johanwinn.bsky.social · Feb 5

🚀 We are looking for Image Data Scientists to join our mission to advance connectomics towards whole brain scale for humans and other mammals (1/3) 🚀

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Jun Axup @junbio.bsky.social · Dec 3

Today, we are excited to share E11 Bio's technology towards whole-brain mammalian brain connectomes!

Andrew Payne @andrewcpayne.bsky.social · Dec 3

🧪 E11 Bio is excited to share a major step towards brain mapping at 100x lower cost, making whole-brain connectomics at human & mouse scale feasible (🧠→🔬→💻). Critical for curing brain disorders, building human-like AI systems, and even simulating human brains.

Read more: e11.bio/news/roadmap

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Reposted by Jun Axup

Andrew Payne @andrewcpayne.bsky.social · Dec 3

🧪 E11 Bio is excited to share a major step towards brain mapping at 100x lower cost, making whole-brain connectomics at human & mouse scale feasible (🧠→🔬→💻). Critical for curing brain disorders, building human-like AI systems, and even simulating human brains.

Read more: e11.bio/news/roadmap

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Jun Axup @junbio.bsky.social · Dec 2

Mapping and understanding the human brain is the path to AI safety! Check out @patrickmineault.bsky.social & Amaranth Foundation's roadmap, which includes our work at @e11bio.bsky.social

Patrick Mineault @patrickmineault.bsky.social · Dec 2

Excited to release what we’ve been working on at Amaranth Foundation, our latest whitepaper, NeuroAI for AI safety! A detailed, ambitious roadmap for how neuroscience research can help build safer AI systems while accelerating both virtual neuroscience and neurotech. 1/N

Different paths toward safe AI at different Marr's levels

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Jun Axup @junbio.bsky.social · Nov 25

I made DNA Argyle Socks 🧬🧦!

Selling a small batch on Etsy for the holidays to spread some science cheer. dnasocks.etsy.com

🧪 #sciart #scicomm

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Jun Axup @junbio.bsky.social · Nov 20

Hi, I'm a chemical biology now working in neuroscience. I also do science art/music. jun.bio

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