Roadtrip. For some, it might be vacation, for others it's a roadtrip from their postdoc to their new lab. I interviewed two scientists who kindly shared personal insight into what that feels like. And yes, they know that many are not having the good fortunate of landing a faculty job just yet. A 🧵

How to spy on condensates: technology feature in
@natmethods.nature.com
Our views on the topic, by Hyman,Rosen,Brangwynne, Sabari, Kappel,Xu & myself, presented here
@hymanlab.bsky.social @brangwynnelab.bsky.social @bsabari.bsky.social @kallikappel.bsky.social
www.nature.com/articles/s41...

Thanks so much Dennis!!

Thanks so much Krishna!!

I will continue building on this approach in my own lab, opening in July at UCLA — if you’re interested in this kind of work, please reach out!

I’m super grateful to all my co-authors for helping to make this project a reality, especially my postdoc advisors Aviv Regev and Feng Zhang.

In the nucleus, many intrinsically disordered proteins (IDPs) form condensates. What IDP sequence features drive this behavior? We developed CondenSeq, a high-throughput approach to measure nuclear condensate formation, and applied it to ~14,000 IDPs to find out!

rdcu.be/eq975