katch wreck
@katchwreck.mastodon.social.ap.brid.gy
i'm in SF & i do biomedical engineering. my focus is to solve the problem of how to better diagnose & treat neurological diseases. i also work on […]
[bridged from https://mastodon.social/@katchwreck on the fediverse by https://fed.brid.gy/ ]
[bridged from https://mastodon.social/@katchwreck on the fediverse by https://fed.brid.gy/ ]
new citation:
Design Strategies toward Precise Protein Sequencing with Biological Nanopores (REVIEW)
https://doi.org/10.1021/acs.analchem.5c05662
#science #nanopore #biosensor #bioengineering #engineering #biology #chemistry #biochemistry #sensing #data #datascience #nanotechnology […]
Design Strategies toward Precise Protein Sequencing with Biological Nanopores (REVIEW)
https://doi.org/10.1021/acs.analchem.5c05662
#science #nanopore #biosensor #bioengineering #engineering #biology #chemistry #biochemistry #sensing #data #datascience #nanotechnology […]
Original post on mastodon.social
mastodon.social
January 4, 2026 at 5:18 AM
new citation:
Design Strategies toward Precise Protein Sequencing with Biological Nanopores (REVIEW)
https://doi.org/10.1021/acs.analchem.5c05662
#science #nanopore #biosensor #bioengineering #engineering #biology #chemistry #biochemistry #sensing #data #datascience #nanotechnology […]
Design Strategies toward Precise Protein Sequencing with Biological Nanopores (REVIEW)
https://doi.org/10.1021/acs.analchem.5c05662
#science #nanopore #biosensor #bioengineering #engineering #biology #chemistry #biochemistry #sensing #data #datascience #nanotechnology […]
the generational disparities in our world could hardly be any starker... older people want to go back to the world of the 19th and 20th centuries, and younger people want to fix the problems that were caused by the older people during those times... but they are politically powerless to do so […]
Original post on mastodon.social
mastodon.social
January 4, 2026 at 5:00 AM
the generational disparities in our world could hardly be any starker... older people want to go back to the world of the 19th and 20th centuries, and younger people want to fix the problems that were caused by the older people during those times... but they are politically powerless to do so […]
`The slash distribution is an example of a ratio distribution. The distribution was named by William H. Rogers and John Tukey in a paper published in 1972`
https://en.wikipedia.org/wiki/Slash_distribution
https://en.wikipedia.org/wiki/Slash_distribution
Slash distribution - Wikipedia
en.wikipedia.org
January 4, 2026 at 12:33 AM
`The slash distribution is an example of a ratio distribution. The distribution was named by William H. Rogers and John Tukey in a paper published in 1972`
https://en.wikipedia.org/wiki/Slash_distribution
https://en.wikipedia.org/wiki/Slash_distribution
`Sputnikmusic's Alex Robertson said that "even when Monk gets nutty, as on the brutally virtuosic 'Trinkle, Tinkle,' the album's appeal lies not in his 'sabotage' of popular music but his ability to turn it into something invigoratingly weird, two approaches often conflated when looking back on […]
Original post on mastodon.social
mastodon.social
January 3, 2026 at 9:57 PM
`Sputnikmusic's Alex Robertson said that "even when Monk gets nutty, as on the brutally virtuosic 'Trinkle, Tinkle,' the album's appeal lies not in his 'sabotage' of popular music but his ability to turn it into something invigoratingly weird, two approaches often conflated when looking back on […]
Reposted by katch wreck
[Huge downer: venue in sf closing]
Bottom of the Hill is closing at the end of this year. I am really heartbroken about this. What a huge loss.
https://www.sfchronicle.com/entertainment/article/bottom-of-the-hill-21273602.php
Bottom of the Hill is closing at the end of this year. I am really heartbroken about this. What a huge loss.
https://www.sfchronicle.com/entertainment/article/bottom-of-the-hill-21273602.php
January 3, 2026 at 4:29 AM
[Huge downer: venue in sf closing]
Bottom of the Hill is closing at the end of this year. I am really heartbroken about this. What a huge loss.
https://www.sfchronicle.com/entertainment/article/bottom-of-the-hill-21273602.php
Bottom of the Hill is closing at the end of this year. I am really heartbroken about this. What a huge loss.
https://www.sfchronicle.com/entertainment/article/bottom-of-the-hill-21273602.php
we take it for granted but before CDs, there wasn't really a "shuffle" mode
January 3, 2026 at 3:59 AM
we take it for granted but before CDs, there wasn't really a "shuffle" mode
`Here... we show that reefs have the potential to increase sustainable yields by nearly 50% if allowed to recover toward their maximum production levels. For individual jurisdictions, this recovery represents from 20,000 up to 162 million additional sustainable servings of reef fish per year in […]
Original post on mastodon.social
mastodon.social
January 2, 2026 at 11:46 PM
`Here... we show that reefs have the potential to increase sustainable yields by nearly 50% if allowed to recover toward their maximum production levels. For individual jurisdictions, this recovery represents from 20,000 up to 162 million additional sustainable servings of reef fish per year in […]
Reposted by katch wreck
A closer look at this helix indicates that it is rich in basic residues: Lys and Arg account for 34% of its sequence composition. This already suggests that its function is to interact with DNA. Looking at sequence conservation, it seems like the basic […]
[Original post on fediscience.org]
[Original post on fediscience.org]
January 2, 2026 at 1:27 PM
A closer look at this helix indicates that it is rich in basic residues: Lys and Arg account for 34% of its sequence composition. This already suggests that its function is to interact with DNA. Looking at sequence conservation, it seems like the basic […]
[Original post on fediscience.org]
[Original post on fediscience.org]
Reposted by katch wreck
I suggest you support Standard Ebooks 📚
“Standard Ebooks is a volunteer-driven project that produces new editions of public domain ebooks that are lovingly formatted, open source, free of … copyright restrictions, and free of cost.” ⚖️
See what’s free to read […]
[Original post on fosstodon.org]
“Standard Ebooks is a volunteer-driven project that produces new editions of public domain ebooks that are lovingly formatted, open source, free of … copyright restrictions, and free of cost.” ⚖️
See what’s free to read […]
[Original post on fosstodon.org]
January 1, 2026 at 9:11 AM
I suggest you support Standard Ebooks 📚
“Standard Ebooks is a volunteer-driven project that produces new editions of public domain ebooks that are lovingly formatted, open source, free of … copyright restrictions, and free of cost.” ⚖️
See what’s free to read […]
[Original post on fosstodon.org]
“Standard Ebooks is a volunteer-driven project that produces new editions of public domain ebooks that are lovingly formatted, open source, free of … copyright restrictions, and free of cost.” ⚖️
See what’s free to read […]
[Original post on fosstodon.org]
Reposted by katch wreck
What do supernovas and EUV lithography have in common? Uncover the explosive story behind Moore's Law's latest chapter, and click to see the rest of IEEE Spectrum's top semiconductor stories this year. https://spectrum.ieee.org/top-semiconductor-stories-2025?share_id=9099607
December 30, 2025 at 2:01 PM
What do supernovas and EUV lithography have in common? Uncover the explosive story behind Moore's Law's latest chapter, and click to see the rest of IEEE Spectrum's top semiconductor stories this year. https://spectrum.ieee.org/top-semiconductor-stories-2025?share_id=9099607
is there a blogger called "snoop bloggy blog" yet :-P
December 30, 2025 at 7:12 AM
is there a blogger called "snoop bloggy blog" yet :-P
Reposted by katch wreck
RRS Sir David Attenborough Webcam via https://www.bas.ac.uk/data/our-data/images/webcams/rrs-sir-david-attenborough-webcam/
Current location: https://www.vesselfinder.com/vessels/details/9798222
#rrssirdavidattenborough #boat #view #webcam #boatymcboatface
Current location: https://www.vesselfinder.com/vessels/details/9798222
#rrssirdavidattenborough #boat #view #webcam #boatymcboatface
December 30, 2025 at 6:32 AM
RRS Sir David Attenborough Webcam via https://www.bas.ac.uk/data/our-data/images/webcams/rrs-sir-david-attenborough-webcam/
Current location: https://www.vesselfinder.com/vessels/details/9798222
#rrssirdavidattenborough #boat #view #webcam #boatymcboatface
Current location: https://www.vesselfinder.com/vessels/details/9798222
#rrssirdavidattenborough #boat #view #webcam #boatymcboatface
"Dynamic recrystallization of the matrix material, size reduction of ceramic particles, as well as interface chemical reaction and phase transformation are found to occur during deposition, resulting in unique composite microstructures. Remarkably, for the first time, stress-induced martensitic […]
Original post on mastodon.social
mastodon.social
December 29, 2025 at 3:12 PM
"Dynamic recrystallization of the matrix material, size reduction of ceramic particles, as well as interface chemical reaction and phase transformation are found to occur during deposition, resulting in unique composite microstructures. Remarkably, for the first time, stress-induced martensitic […]
with sufficient automation, provenance can be achieved by copying input parameters into all outputs
December 29, 2025 at 8:07 AM
with sufficient automation, provenance can be achieved by copying input parameters into all outputs
`Sirius is colloquially known as the "Dog Star", reflecting its prominence in its constellation, Canis Major (the Greater Dog).`
https://en.wikipedia.org/wiki/Sirius
https://en.wikipedia.org/wiki/Sirius
Sirius - Wikipedia
en.wikipedia.org
December 29, 2025 at 7:07 AM
`Sirius is colloquially known as the "Dog Star", reflecting its prominence in its constellation, Canis Major (the Greater Dog).`
https://en.wikipedia.org/wiki/Sirius
https://en.wikipedia.org/wiki/Sirius
Reposted by katch wreck
One of the most incredible shots I've ever gotten, in Yellowstone. This coyote walked over a ridge in the blowing snow and posed for me, with a small grin on its face, the snowfalkes like stars in the background.
The desolation and beauty of life and nature is grounding, and so good for the soul.
The desolation and beauty of life and nature is grounding, and so good for the soul.
December 28, 2025 at 2:03 AM
One of the most incredible shots I've ever gotten, in Yellowstone. This coyote walked over a ridge in the blowing snow and posed for me, with a small grin on its face, the snowfalkes like stars in the background.
The desolation and beauty of life and nature is grounding, and so good for the soul.
The desolation and beauty of life and nature is grounding, and so good for the soul.
here's a fun game: try coding on a machine with no ethernet or wifi adapter at all, so you are completely unable to procrastinate online, and count how many times you almost open a browser :)
December 28, 2025 at 5:27 AM
here's a fun game: try coding on a machine with no ethernet or wifi adapter at all, so you are completely unable to procrastinate online, and count how many times you almost open a browser :)
it's snowing hard here in Albany NY! haven't seen this in a while :)
December 27, 2025 at 12:14 AM
it's snowing hard here in Albany NY! haven't seen this in a while :)
`In humans and mice, pathology severity correlates with disruption of brain NAD+ homeostasis, and the brains of nondemented people with Alzheimer’s neuropathology exhibit gene expression patterns suggestive of preserved NAD+ homeostasis. Forty-six proteins aberrantly expressed in advanced 5xFAD […]
Original post on mastodon.social
mastodon.social
December 26, 2025 at 10:34 PM
`In humans and mice, pathology severity correlates with disruption of brain NAD+ homeostasis, and the brains of nondemented people with Alzheimer’s neuropathology exhibit gene expression patterns suggestive of preserved NAD+ homeostasis. Forty-six proteins aberrantly expressed in advanced 5xFAD […]
it was sad when biden ruined christmas but i'm sure glad it's been saved by those among us with the best DNA! they have restored it to its true meaning: killing nigerian muslims with bombs. now, we can truly celebrate as one, as the god of the supreme race has commanded! yay
December 26, 2025 at 4:28 AM
it was sad when biden ruined christmas but i'm sure glad it's been saved by those among us with the best DNA! they have restored it to its true meaning: killing nigerian muslims with bombs. now, we can truly celebrate as one, as the god of the supreme race has commanded! yay
imagine bragging about bringing Christmas back, then launching strikes in Nigeria on Christmas, and then bragging about killing people with the bombs you dropped as part of Christmas.
#lunacy
#lunacy
December 26, 2025 at 4:22 AM
imagine bragging about bringing Christmas back, then launching strikes in Nigeria on Christmas, and then bragging about killing people with the bombs you dropped as part of Christmas.
#lunacy
#lunacy
here's a cute melody that i literally dreamed up the other day and then fleshed out based on what i remembered from my dream :)
happy holidays!
#happyholidays #merrychristmas #melody #dream #music
happy holidays!
#happyholidays #merrychristmas #melody #dream #music
December 26, 2025 at 2:38 AM
here's a cute melody that i literally dreamed up the other day and then fleshed out based on what i remembered from my dream :)
happy holidays!
#happyholidays #merrychristmas #melody #dream #music
happy holidays!
#happyholidays #merrychristmas #melody #dream #music
fun sci-fi novel idea: society splits into "analog" and "digital" ideological factions, and try to segregate their territories and have territorial conflicts involving contrasting technologies
December 25, 2025 at 8:04 AM
fun sci-fi novel idea: society splits into "analog" and "digital" ideological factions, and try to segregate their territories and have territorial conflicts involving contrasting technologies
it saddens me to see a new wave of bigotry emerging from within the most privileged classes of our society... and seeing the wealthiest among us pour their energies into indoctrinating new generations in the very bigotry the majority classes abhor
December 25, 2025 at 5:52 AM
it saddens me to see a new wave of bigotry emerging from within the most privileged classes of our society... and seeing the wealthiest among us pour their energies into indoctrinating new generations in the very bigotry the majority classes abhor
`The Dirichlet and logistic normal distributions are never exactly equal for any choice of parameters. However, Aitchison described a method for approximating a Dirichlet with a logistic normal such that their Kullback–Leibler divergence (KL) is minimized` […]
Original post on mastodon.social
mastodon.social
December 25, 2025 at 5:40 AM
`The Dirichlet and logistic normal distributions are never exactly equal for any choice of parameters. However, Aitchison described a method for approximating a Dirichlet with a logistic normal such that their Kullback–Leibler divergence (KL) is minimized` […]