katemorling.bsky.social
Kate Morling
@katemorling.bsky.social
26 followers 30 following 2 posts
Postdoctoral Research Fellow working on HIV in Towers Lab UCL 🦠
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katemorling.bsky.social
Kate Morling @katemorling.bsky.social · Sep 2
@lsnewton.bsky.social @ali-hashim.bsky.social @mattvxwhelan.bsky.social @rsbmilne.bsky.social
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katemorling.bsky.social
Kate Morling @katemorling.bsky.social · Sep 2
Excited to share the preprint for our work on cyclosporine-based lentiviral transduction enhancer, BG147, which degrades innate immune barrier IFITM3, increasing gene delivery in gene therapy.

Huge thanks to everyone involved! @towerslab.bsky.social

www.biorxiv.org/content/10.1...
A modified cyclosporine enhances lentivector transduction ex vivo and in vivo by degrading IFITM3
Intrinsic innate immune barriers have evolved to suppress viral infection and can reduce effective gene delivery in gene therapy. We have developed BG147, a novel cyclosporine A analogue, optimised vi...
www.biorxiv.org
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Reposted by Kate Morling
melghazaly.bsky.social
Mohamed Elghazaly @melghazaly.bsky.social · Jun 9
Towers Lab attending @londoninfectionecr.bsky.social (LINE) annual symposium. Great talk lineups at the Francis Crick Institute, London. #LINE #ScienceIsCool.
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Reposted by Kate Morling
rsbmilne.bsky.social
RM @rsbmilne.bsky.social · May 8
Virtual Virology is back - our first ever phage session. Do join us...
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Reposted by Kate Morling
towerslab.bsky.social
Towers Lab @towerslab.bsky.social · Jan 14
First paper of 2025 is out now! 🎉

Our talented postdocs @katemorling.bsky.social and @melghazaly.bsky.social review latest advancements of how HIV capsid and accessory proteins Vpx/Vpr have evolved (or not) to regulate host innate immunity.

www.microbiologyresearch.org/content/jour...
Early events in the HIV life cycle.
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