Becker et. al developed a proteomic proximity labeling platform named POCA, which makes use of a photosensitizer for singlet oxygen production and protein capture in the presence of amine, enabling pr...

Cholesterol plays a central role in cell health, influencing membrane fluidity, curvature, and signaling. To maintain proper cholesterol levels, cells rely on tightly regulated transport systems that move cholesterol between membranes and organelles. However, many of the proteins involved in sensing, binding, and trafficking cholesterol—and how they dynamically interact—remain poorly understood.